QuickView for HMOX1;jsessionid=6035109A7548FDD017160F3ECFF1C66B;jsessionid=B82E29DEBDD8D9B34CE3F2962D1735D7 (gene)
- Gene Symbol:
- Hmox1
Rattus norvegicus - Full name:
- heme oxygenase 1
- Synonyms:
- HEOXG, Heox, Hmox, Ho-1, Ho1, hsp32, heme oxygenase 1, heme oxygenase (decycling) 1, heme oxygenase (decyclizing) 1
- Genomic Location:
- Chr 19: 13963139-13969960
- Description:
-
catalyzes the oxidative cleavage of heme to biliverdin
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NMYC_01 , USF_01 , USF_C , MYCMAX_03 , USF_Q6_01 , CREB_Q3 , AAGCACA_MIR218 , TGTGTGA_MIR377 , CAGCTG_AP4_Q5 , CACGTG_MYC_Q2
- miRNA binding sites
(Source: TargetScan):
- miRNA binding sites
(Source: miRecords):
GO Molecular Function
cofactor binding | cation binding | phospholipase activity | enzyme binding | hydrolase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | hydrolase activity, acting on ester bonds | identical protein binding | phospholipase D activity | ion binding | organic cyclic compound binding | heme oxygenase (decyclizing) activity | lipase activity | tetrapyrrole binding | protein binding | protein homodimerization activity | protein dimerization activity | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
negative regulation of leukocyte activation | positive regulation of smooth muscle cell proliferation | response to extracellular stimulus | protein homooligomerization | negative regulation of intracellular transport | cellular response to decreased oxygen levels | positive regulation of locomotion | response to nutrient levels | negative regulation of immune system process | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | erythrocyte homeostasis | regulation of autophagy | regulation of immune system process | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | response to metal ion | positive regulation of epithelial cell proliferation | defense response | intrinsic apoptotic signaling pathway in response to DNA damage | cellular response to extracellular stimulus | response to drug | regulation of sprouting angiogenesis | cellular chemical homeostasis | cellular response to iron ion | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | response to antibiotic | phospholipid metabolic process | blood vessel morphogenesis | regulation of neuron death | cellular process | organic substance catabolic process | regulation of cell motility | cellular homeostasis | negative regulation of macroautophagy | negative regulation of signaling | positive regulation of immune effector process | negative regulation of apoptotic process | negative regulation of secretion | response to hypoxia | response to inorganic substance | negative regulation of cellular metabolic process | regulation of binding | negative regulation of mast cell activation | heme metabolic process | intrinsic apoptotic signaling pathway | porphyrin-containing compound metabolic process | negative regulation of apoptotic signaling pathway | regeneration | response to hydrogen peroxide | regulation of angiogenesis | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | hepaticobiliary system development | small GTPase mediated signal transduction | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | cellular lipid metabolic process | regulation of mast cell degranulation | cellular response to metal ion | positive regulation of epithelial cell migration | heme catabolic process | regulation of vasculature development | response to stimulus | negative regulation of epithelial cell apoptotic process | vasculature development | positive regulation of immune system process | cellular response to hypoxia | response to stress | regulation of cell proliferation | tube morphogenesis | programmed cell death | cellular response to inorganic substance | cardiovascular system development | response to temperature stimulus | positive regulation of sprouting angiogenesis | cellular response to cadmium ion | cellular nitrogen compound metabolic process | cellular response to toxic substance | cellular response to cisplatin | regulation of macroautophagy | negative regulation of transport | regulation of DNA binding | positive regulation of blood vessel endothelial cell migration | blood circulation | negative regulation of metabolic process | cofactor metabolic process | cellular component assembly | response to iron ion | regulation of intracellular transport | metal ion homeostasis | blood vessel development | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | negative regulation of neuron apoptotic process | apoptotic process | response to nicotine | system development | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | inflammatory response to wounding | phosphorus metabolic process | cellular response to DNA damage stimulus | protein complex oligomerization | lipid metabolic process | cellular response to oxidative stress | wound healing | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | regulation of blood pressure | organophosphate metabolic process | cellular response to heat | negative regulation of cytokine production | positive regulation of cellular metabolic process | negative regulation of mast cell cytokine production | heme oxidation | cellular ion homeostasis | negative regulation of smooth muscle cell proliferation | liver development | cellular response to oxygen levels | regulation of mast cell activation | regulation of nitrogen compound metabolic process | regulation of cell migration | negative regulation of DNA-binding transcription factor activity | negative regulation of DNA binding | regulation of cellular component movement | regulation of transcription by RNA polymerase II | response to nutrient | response to oxidative stress | regulation of cell migration involved in sprouting angiogenesis | negative regulation of binding | regulation of endothelial cell migration | regulation of transcription from RNA polymerase II promoter in response to oxidative stress | negative regulation of extrinsic apoptotic signaling pathway | homeostasis of number of cells | positive regulation of cell migration | response to cadmium ion | negative regulation of immune response | angiogenesis | response to toxic substance | regulation of apoptotic signaling pathway | regulation of epithelial cell apoptotic process | cation homeostasis | phosphate-containing compound metabolic process | negative regulation of autophagy | cellular response to drug | heme oxygenase (decyclizing) activity | response to cisplatin | response to estrogen | regulation of muscle cell apoptotic process | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | liver regeneration | regulation of neuron apoptotic process | negative regulation of cell activation | inflammatory response | regulation of cytokine production involved in immune response | aromatic compound catabolic process | homeostatic process | positive regulation of cell proliferation | regulation of locomotion | iron ion homeostasis | regulation of RNA metabolic process | negative regulation of vascular smooth muscle cell proliferation | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | negative regulation of mast cell activation involved in immune response | apoptotic signaling pathway | wound healing involved in inflammatory response | negative regulation of exocytosis | protein-containing complex assembly | cellular response to nutrient | gland development | response to wounding | response to antineoplastic agent | regulation of DNA-binding transcription factor activity | regulation of exocytosis | anatomical structure development | metabolic process | regulation of DNA-templated transcription in response to stress | cellular response to arsenic-containing substance | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of programmed cell death | regulation of vesicle-mediated transport | negative regulation of muscle cell apoptotic process | chemical homeostasis | regulation of secretion | positive regulation of cell death | organic substance metabolic process | cell death | pigment metabolic process | animal organ development | response to reactive oxygen species | regulation of endothelial cell proliferation | regulation of cell activation | positive regulation of programmed cell death | response to heat | ion homeostasis | cellular iron ion homeostasis | positive regulation of autophagy | regulation of regulated secretory pathway | positive regulation of macroautophagy | positive regulation of endothelial cell migration | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | organonitrogen compound catabolic process | regulation of cell communication | regulation of blood vessel endothelial cell migration | negative regulation of molecular function | negative regulation of signal transduction | response to arsenic-containing substance | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | regulation of transcription, DNA-templated | positive regulation of cell migration involved in sprouting angiogenesis | regulation of epithelial cell proliferation | regulation of transcription from RNA polymerase II promoter in response to stress | regulation of cytokine production | anatomical structure morphogenesis | regulation of transcription from RNA polymerase II promoter in response to iron | regulation of developmental process | developmental process | tube development | regulation of transport | negative regulation of cell proliferation | cellular metal ion homeostasis | heterocycle metabolic process | positive regulation of metabolic process | transition metal ion homeostasis | immune system process | cellular metabolic process | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of cell motility | oxidoreductase activity | negative regulation of cell death | circulatory system development | positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | positive regulation of angiogenesis | negative regulation of mast cell degranulation | signal transduction | regulation of signaling | animal organ regeneration | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | membrane raft | perinuclear region of cytoplasm | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | plasma membrane raft | cytosol | intracellular | caveola | membrane
