QuickView for HPGD;jsessionid=1138FBE1152D435A967DBA193456A48B;jsessionid=F08023EF191FD0868A0B4F546BC64087 (gene)
- Gene Symbol:
- Hpgd
Mus musculus - Full name:
- hydroxyprostaglandin dehydrogenase 15 (NAD)
- Synonyms:
- 15-PGDH, AV026552, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 15-hydroxyprostaglandin dehydrogenase, PGDH, prostaglandin dehydrogenase 1
- Genomic Location:
- Chr 8: 58773349-58799843
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | cofactor binding | prostaglandin receptor activity | transmembrane signaling receptor activity | nucleotide binding | G-protein coupled receptor activity | coenzyme binding | NAD+ binding | catalytic activity | anion binding | signaling receptor activity | identical protein binding | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | prostaglandin E receptor activity | NAD binding | protein dimerization activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
positive regulation of smooth muscle cell proliferation | oxidoreductase activity, acting on CH-OH group of donors | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | response to drug | response to antibiotic | blood vessel morphogenesis | positive regulation of vascular smooth muscle cell proliferation | prostaglandin receptor activity | cellular process | female pregnancy | regulation of cell cycle | response to growth factor | regulation of cellular process | parturition | regulation of apoptotic process | cellular lipid metabolic process | response to transforming growth factor beta | G-protein coupled receptor activity | response to stimulus | vasculature development | monocarboxylic acid metabolic process | regulation of cell proliferation | tube morphogenesis | reproduction | response to alcohol | cardiovascular system development | ductus arteriosus closure | G-protein coupled receptor signaling pathway | blood vessel development | response to ethanol | system development | reproductive process | multicellular organism development | lipid metabolic process | artery development | enzyme linked receptor protein signaling pathway | small molecule metabolic process | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | response to toxic substance | cell communication | transmembrane receptor protein serine/threonine kinase signaling pathway | positive regulation of cell proliferation | carboxylic acid metabolic process | cellular response to transforming growth factor beta stimulus | response to organic substance | artery morphogenesis | prostaglandin E receptor activity | anatomical structure development | cell surface receptor signaling pathway | metabolic process | oxidation-reduction process | prostaglandin metabolic process | positive regulation of cell death | organic substance metabolic process | positive regulation of programmed cell death | fatty acid metabolic process | transforming growth factor beta receptor signaling pathway | negative regulation of cell cycle | icosanoid metabolic process | signaling | organic acid metabolic process | anatomical structure morphogenesis | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | developmental process | tube development | cellular metabolic process | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | oxidoreductase activity | circulatory system development | signal transduction | cellular response to growth factor stimulus | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | plasma membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | basolateral plasma membrane | cytosol | intracellular | membrane
