QuickView for HSD11B2;jsessionid=C9D2AAD3A03BCCA8794858A15BE0AD82;jsessionid=3094AD448703EB7AEEF51FABB84CD545 (gene)
- Gene Symbol:
- Hsd11b2
Rattus norvegicus - Full name:
- hydroxysteroid 11-beta dehydrogenase 2
- Synonyms:
- corticosteroid 11-beta-dehydrogenase isozyme 2, 11-DH2, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type 2, Hydroxysteroid dehydrogenase, 11 beta type 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase
- Genomic Location:
- Chr 19: 35336342-35341585
- Description:
-
catalyzes the conversion of corticosterone to 11-dehydrocorticosterone
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Danio rerio , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFKAPPAB_01 , MYOD_Q6 , AP2ALPHA_01 , E12_Q6 , MYOGENIN_Q6 , NFKB_Q6_01 , SP1_Q2_01 , CTCAAGA_MIR526B , CAGGTG_E12_Q6 , CTTTGT_LEF1_Q2
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | steroid dehydrogenase activity | cofactor binding | lipid binding | nucleotide binding | coenzyme binding | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | catalytic activity | organic cyclic compound binding | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | NAD binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | steroid binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
response to extracellular stimulus | response to nutrient levels | regulation of systemic arterial blood pressure by hormone | oxidoreductase activity, acting on CH-OH group of donors | steroid dehydrogenase activity | response to hormone | response to drug | female pregnancy | response to hypoxia | response to peptide hormone | organic cyclic compound metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | response to stimulus | positive regulation of blood pressure | response to stress | response to peptide | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | reproduction | blood circulation | response to nitrogen compound | response to oxygen levels | reproductive process | lipid metabolic process | regulation of hormone levels | response to lipid | regulation of blood pressure | regulation of systemic arterial blood pressure | response to corticosteroid | regulation of blood volume by renal aldosterone | endocrine process | positive regulation of systemic arterial blood pressure | response to organic substance | response to insulin | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | metabolic process | regulation of body fluid levels | oxidation-reduction process | organic substance metabolic process | renal system process | steroid metabolic process | glucocorticoid metabolic process | response to organic cyclic compound | hormone metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | renal system process involved in regulation of systemic arterial blood pressure | response to organonitrogen compound | oxidoreductase activity | response to steroid hormone | response to food | response to glucocorticoid | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | endomembrane system | membrane-bounded organelle | organelle | intracellular
