QuickView for HSP60;jsessionid=22609855EA2B42EFF7F851FCF3EB2E59;jsessionid=FDD4CB5E40E2A7F217D4387E4B612A0C (gene)

Gene Symbol:

HSPD1 Homo sapiens

Full name:

heat shock protein family D (Hsp60) member 1

Synonyms:

CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13, 60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, P60 lymphocyte protein, chaperonin 60, heat shock 60kDa protein 1 (chaperonin), heat shock protein 65, mitochondrial matrix protein P1, short heat shock protein 60 Hsp60s1

Genomic Location:

Chr 2: 198059553-198073243

Description:

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions ...

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This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACAACCT_MIR453 ,  STAT1_02 ,  ARNT_01 ,  CACGTG_MYC_Q2 ,  E4BP4_01 ,  TTCNRGNNNNTTC_HSF_Q6 ,  STAT1_03 ,  TGACCTY_ERR1_Q2 ,  WHN_B ,  CREB_Q3 ,  HNF4_DR1_Q3 ,  GGGAGGRR_MAZ_Q6 ,  STAT_Q6 ,  HNF4_01 ,  RGAANNTTC_HSF1_01 ,  ACATTCC_MIR1_MIR206 ,  DR1_Q3 ,  HSF1_01 ,  TTCYRGAA_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  GCGNNANTTCC_UNKNOWN ,  HSF_Q6 ,  HSF2_01 ,  RORA1_01 ,  NMYC_01 ,  COUP_DR1_Q6 ,  CCGNMNNTNACG_UNKNOWN ,  RCGCANGCGY_NRF1_Q6 ,  ERR1_Q2 ,  TGACCTTG_SF1_Q6 ,  AGGAAGC_MIR5163P ,  SF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-382 ,  Predicted Gene Targets for miR-421

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

2q33.1

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