QuickView for HTR2A;jsessionid=38E121C11C4D3F9AEBDC528024039AC2;jsessionid=A512C3883C2793E416EE874096F2DECB (gene)
- Gene Symbol:
- Htr2a
Rattus norvegicus - Full name:
- 5-hydroxytryptamine receptor 2A
- Synonyms:
- 5-HT2A, 5Ht-2, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled, serotonin 5HT-2 receptor, serotonin receptor 2A
- Genomic Location:
- Chr 15: 55463743-55532293
- Description:
-
a receptor for 5-hydroxytryptamine (serotonin); activates phospholipase C signaling pathway; involved in promoting cellular transformation
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Canis lupus familiaris , Bos taurus , Gallus gallus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
neurotransmitter receptor activity | cation binding | neurotransmitter binding | transmembrane signaling receptor activity | protein-containing complex binding | G-protein coupled receptor activity | G-protein coupled amine receptor activity | serotonin binding | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding | signaling receptor activity | ion binding | organic cyclic compound binding | amine binding | protein binding | G-protein coupled serotonin receptor activity | drug binding | G-protein alpha-subunit binding | heterocyclic compound binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | regulation of blood vessel diameter | positive regulation of blood circulation | detection of stimulus | positive regulation of ATP metabolic process | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | regulation of carbohydrate metabolic process | vascular smooth muscle contraction | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | negative regulation of potassium ion transport | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | detection of mechanical stimulus involved in sensory perception | response to drug | cellular chemical homeostasis | positive regulation of phosphate metabolic process | tonic smooth muscle contraction | sensory perception of mechanical stimulus | positive regulation of phosphatidylinositol biosynthetic process | artery smooth muscle contraction | positive regulation of cellular biosynthetic process | cellular process | regulation of catecholamine secretion | localization | cellular homeostasis | regulation of glycolytic process | negative regulation of signaling | metal ion transport | chemical synaptic transmission | positive regulation of protein kinase activity | macromolecule localization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | activation of phospholipase C activity | establishment of localization in cell | regulation of fat cell differentiation | regulation of cell differentiation | positive regulation of vasoconstriction | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | smooth muscle contraction | calcium ion homeostasis | G-protein coupled receptor activity | calcium ion transport into cytosol | muscle contraction | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | regulation of blood vessel size | response to cocaine | regulation of response to drug | regulation of cell proliferation | positive regulation of lipid biosynthetic process | multicellular organismal homeostasis | regulation of blood circulation | sensory perception of temperature stimulus | G-protein coupled amine receptor activity | phosphatidylinositol-mediated signaling | cellular localization | divalent metal ion transport | response to temperature stimulus | positive regulation of lipase activity | negative regulation of transport | blood circulation | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | modulation of chemical synaptic transmission | cell-cell signaling | metal ion homeostasis | urinary bladder smooth muscle contraction | detection of temperature stimulus involved in sensory perception | negative regulation of blood vessel diameter | detection of abiotic stimulus | positive regulation of phospholipase C activity | response to nitrogen compound | regulation of signal transduction | regulation of synaptic transmission, glutamatergic | calcium ion transmembrane transport | regulation of MAPK cascade | learning or memory | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ion transmembrane transport | detection of mechanical stimulus involved in sensory perception of pain | regulation of phospholipid biosynthetic process | nervous system process | synaptic signaling | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | sleep | phospholipase C-activating serotonin receptor signaling pathway | response to ammonium ion | positive regulation of ATP biosynthetic process | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | protein localization to organelle | positive regulation of hydrolase activity | behavioral response to cocaine | positive regulation of cell differentiation | cognition | positive regulation of glycolytic process | negative regulation of sequestering of calcium ion | sensory perception of pain | regulation of cellular protein metabolic process | vasoconstriction | negative regulation of ion transport | regulation of phospholipase activity | inositol lipid-mediated signaling | detection of temperature stimulus involved in sensory perception of pain | response to xenobiotic stimulus | cation homeostasis | negative regulation of synaptic transmission, glutamatergic | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of tube size | regulation of phospholipid metabolic process | regulation of lipid biosynthetic process | regulation of dopamine secretion | regulation of potassium ion transport | regulation of phospholipase C activity | positive regulation of molecular function | release of sequestered calcium ion into cytosol | cation transmembrane transport | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | response to mechanical stimulus | detection of stimulus involved in sensory perception | regulation of intracellular signal transduction | phosphatidylinositol 3-kinase signaling | regulation of vasoconstriction | regulation of tube diameter | cellular protein localization | chemical homeostasis | calcium ion transport | regulation of secretion | behavior | regulation of sequestering of calcium ion | cell death | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | ion homeostasis | regulation of ATP metabolic process | regulation of phosphate metabolic process | G-protein coupled serotonin receptor activity | inorganic cation transmembrane transport | response to alkaloid | phospholipase C-activating G-protein coupled receptor signaling pathway | detection of mechanical stimulus | positive regulation of phospholipase activity | positive regulation of MAPK cascade | temperature homeostasis | memory | adult behavior | sensory perception | positive regulation of carbohydrate metabolic process | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | transmembrane transport | signaling | response to organic cyclic compound | protein localization | positive regulation of phosphorylation | cation transport | cellular macromolecule localization | positive regulation of fat cell differentiation | positive regulation of MAP kinase activity | G-protein coupled serotonin receptor signaling pathway | regulation of developmental process | regulation of ion transport | developmental process | detection of temperature stimulus | positive regulation of phospholipid biosynthetic process | regulation of transport | serotonin receptor signaling pathway | response to organonitrogen compound | cellular metal ion homeostasis | protein localization to cytoskeleton | negative regulation of synaptic transmission | response to anesthetic | regulation of generation of precursor metabolites and energy | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | ion transport | aging | divalent inorganic cation homeostasis | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | cytoplasm | intracellular organelle | membrane microdomain | dendritic tree | cell projection | plasma membrane | membrane raft | vesicle | cell body fiber | integral component of plasma membrane | membrane-bounded organelle | dendritic shaft | organelle | cell periphery | axon | plasma membrane raft | cytosol | intracellular vesicle | intracellular | caveola | membrane | intrinsic component of plasma membrane
