QuickView for HTR2B;jsessionid=031D1518A698BBF66F513997229B9CEE;jsessionid=CA83BE777897CAFBB6308B733353829F (gene)
- Gene Symbol:
- Htr2b
Mus musculus - Full name:
- 5-hydroxytryptamine (serotonin) receptor 2B
- Synonyms:
- 5-HT2B, AJ012488, AV377389, 5-hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT-2F, NP75 protein, serotonin receptor 2B
- Genomic Location:
- Chr 1: 87995612-88008545
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
enzyme activator activity | neurotransmitter receptor activity | cation binding | GTPase activator activity | neurotransmitter binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | GTPase regulator activity | G-protein coupled amine receptor activity | serotonin binding | molecular function regulator | signaling receptor activity | ion binding | organic cyclic compound binding | amine binding | protein binding | G-protein coupled serotonin receptor activity | enzyme regulator activity | drug binding | G-protein alpha-subunit binding | heterocyclic compound binding
GO Biological Process
negative regulation of G-protein coupled receptor protein signaling pathway | regulation of ERK1 and ERK2 cascade | regulation of blood vessel diameter | cell motility | intracellular signal transduction | enzyme activator activity | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | regulation of programmed cell death | establishment of localization | regulation of autophagy | negative regulation of cellular process | regulation of MAP kinase activity | cell differentiation | positive regulation of epithelial cell proliferation | response to drug | cellular chemical homeostasis | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of protein secretion | mesenchyme development | positive regulation of GTPase activity | positive regulation of phosphatidylinositol biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | localization | cellular homeostasis | heart morphogenesis | negative regulation of signaling | metal ion transport | chemical synaptic transmission | cellular response to temperature stimulus | positive regulation of nitric-oxide synthase activity | GTPase activator activity | positive regulation of protein kinase activity | negative regulation of apoptotic process | positive regulation of oxidoreductase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | activation of phospholipase C activity | establishment of localization in cell | negative regulation of cellular metabolic process | regulation of behavior | tissue development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | G-protein coupled receptor internalization | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | smooth muscle contraction | MAPK cascade | calcium ion homeostasis | regulation of cell division | G-protein coupled receptor activity | calcium ion transport into cytosol | regulation of peptide secretion | muscle contraction | response to stimulus | mesenchymal cell development | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | regulation of blood vessel size | GTPase regulator activity | regulation of cell proliferation | positive regulation of lipid biosynthetic process | G-protein coupled amine receptor activity | phosphatidylinositol-mediated signaling | cellular localization | divalent metal ion transport | positive regulation of cytokine secretion | response to temperature stimulus | positive regulation of lipase activity | cellular response to organic cyclic compound | regulation of protein transport | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | protein modification process | regulation of peptide transport | embryo development | macromolecule modification | cell-cell signaling | molecular function regulator | metal ion homeostasis | negative regulation of blood vessel diameter | positive regulation of peptide secretion | positive regulation of monooxygenase activity | locomotion | positive regulation of phospholipase C activity | response to nitrogen compound | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | cell migration | calcium ion transmembrane transport | cGMP-mediated signaling | regulation of MAPK cascade | phosphorus metabolic process | cellular response to serotonin | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ion transmembrane transport | regulation of nitric-oxide synthase activity | cellular response to ammonium ion | regulation of phospholipid biosynthetic process | protein kinase C signaling | positive regulation of secretion | synaptic signaling | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | animal organ morphogenesis | phospholipase C-activating serotonin receptor signaling pathway | response to ammonium ion | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | vesicle-mediated transport | positive regulation of hydrolase activity | second-messenger-mediated signaling | stem cell differentiation | cellular response to amine stimulus | gastro-intestinal system smooth muscle contraction | cardiac muscle hypertrophy | negative regulation of sequestering of calcium ion | regulation of cellular protein metabolic process | vasoconstriction | phosphorylation | regulation of phospholipase activity | inositol lipid-mediated signaling | regulation of GTPase activity | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | negative regulation of autophagy | neural crest cell migration | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | receptor internalization | intestine smooth muscle contraction | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | positive regulation of signal transduction | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | protein kinase C-activating G-protein coupled receptor signaling pathway | regulation of tube size | positive regulation of transport | regulation of phospholipid metabolic process | regulation of lipid biosynthetic process | embryonic morphogenesis | negative adaptation of signaling pathway | regulation of phospholipase C activity | positive regulation of molecular function | release of sequestered calcium ion into cytosol | calcium-mediated signaling | regulation of cytokine secretion | cation transmembrane transport | response to monoamine | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | import into cell | regulation of intracellular signal transduction | phosphatidylinositol 3-kinase signaling | anatomical structure development | response to amine | metabolic process | mesenchymal cell differentiation | negative regulation of programmed cell death | regulation of tube diameter | chemical homeostasis | calcium ion transport | endocytosis | regulation of secretion | behavior | organic substance metabolic process | regulation of sequestering of calcium ion | animal organ development | regulation of endothelial cell proliferation | response to serotonin | regulation of protein secretion | positive regulation of ERK1 and ERK2 cascade | desensitization of G-protein coupled receptor protein signaling pathway | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | G-protein coupled serotonin receptor activity | inorganic cation transmembrane transport | phospholipase C-activating G-protein coupled receptor signaling pathway | positive regulation of cytokine production | positive regulation of phospholipase activity | positive regulation of MAPK cascade | stem cell development | positive regulation of protein transport | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of signal transduction | transmembrane transport | signaling | regulation of oxidoreductase activity | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | regulation of cytokine production | anatomical structure morphogenesis | cation transport | positive regulation of MAP kinase activity | G-protein coupled serotonin receptor signaling pathway | receptor-mediated endocytosis | regulation of G-protein coupled receptor protein signaling pathway | developmental process | cellular protein modification process | positive regulation of phospholipid biosynthetic process | regulation of transport | receptor metabolic process | serotonin receptor signaling pathway | response to organonitrogen compound | neural crest cell differentiation | cellular metal ion homeostasis | ERK1 and ERK2 cascade | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | ion transport | cellular metabolic process | ameboidal-type cell migration | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | circulatory system development | muscle hypertrophy | divalent inorganic cation homeostasis | neural crest cell development | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell body | cell | nuclear lumen | neuronal cell body | intrinsic component of membrane | cytoplasm | intracellular organelle | dendritic tree | cell projection | nucleoplasm | plasma membrane | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | intracellular | cell junction | membrane | intrinsic component of plasma membrane
