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QuickView for Hprt1;jsessionid=F78148EDC92AF0A148EB5DFB199550D7;jsessionid=68F34C4D55A8B2959F912E6F4DF1C0C9 (gene)


Gene Symbol:
HPRT1 Canis lupus familiaris Canis lupus familiaris
Full name:
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)
Synonyms:
HPRT
Genomic Location:
Chr X: 108191277-108214931
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus C. elegans Macaca mulatta Bos taurus Gallus gallus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001003357
Protein Names
Q6WIT9



GO Molecular Function

guanine phosphoribosyltransferase activity | cation binding | magnesium ion binding | nucleotide binding | catalytic activity | identical protein binding | transferase activity, transferring glycosyl groups | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | protein dimerization activity | transferase activity, transferring pentosyl groups | transferase activity | hypoxanthine phosphoribosyltransferase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

brain development | purine ribonucleotide metabolic process | protein homooligomerization | adaptive immune response | cell morphogenesis | purine ribonucleoside monophosphate biosynthetic process | adenine salvage | GMP metabolic process | neuron projection morphogenesis | nucleoside phosphate catabolic process | catechol-containing compound metabolic process | subpallium development | hypoxanthine biosynthetic process | cell differentiation | nervous system development | response to drug | organophosphate catabolic process | cell part morphogenesis | neurogenesis | generation of neurons | nucleoside catabolic process | phenol-containing compound metabolic process | cellular process | organic substance catabolic process | cell projection morphogenesis | nucleotide metabolic process | neuron development | central nervous system neuron differentiation | carbohydrate derivative catabolic process | cerebral cortex neuron differentiation | ribose phosphate metabolic process | purine nucleotide biosynthetic process | positive regulation of nitrogen compound metabolic process | ribonucleotide metabolic process | purine nucleoside catabolic process | regulation of cellular process | leukocyte activation | regulation of metabolic process | guanine salvage | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | head development | response to stimulus | purine nucleotide metabolic process | cell morphogenesis involved in neuron differentiation | hypoxanthine salvage | mononuclear cell proliferation | cellular nitrogen compound biosynthetic process | GMP catabolic process | purine nucleobase biosynthetic process | cellular nitrogen compound metabolic process | regulation of dopamine metabolic process | purine nucleotide salvage | carbohydrate derivative biosynthetic process | cellular component assembly | cellular biosynthetic process | purine nucleoside metabolic process | nucleobase-containing compound catabolic process | dopamine metabolic process | purine nucleoside monophosphate catabolic process | nucleotide biosynthetic process | regulation of catecholamine metabolic process | organic hydroxy compound metabolic process | response to nitrogen compound | central nervous system neuron development | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | system development | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | purine ribonucleoside catabolic process | protein complex oligomerization | leukocyte mediated immunity | telencephalon development | cell killing | organophosphate metabolic process | nucleoside metabolic process | positive regulation of cellular metabolic process | positive regulation of dopamine metabolic process | nucleobase-containing small molecule catabolic process | striatum development | pigment biosynthetic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | adenine metabolic process | protein homotetramerization | nucleobase-containing small molecule metabolic process | cell proliferation | leukocyte proliferation | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | purine ribonucleotide biosynthetic process | nucleotide catabolic process | protein tetramerization | response to toxic substance | response to xenobiotic stimulus | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | T cell mediated immunity | purine ribonucleoside salvage | aromatic compound catabolic process | drug metabolic process | lymphocyte activation | neuron differentiation | protein-containing complex assembly | response to organic substance | T cell mediated cytotoxicity | catecholamine metabolic process | anatomical structure development | response to amine | cell projection organization | metabolic process | behavior | immune response | leukocyte mediated cytotoxicity | nucleobase-containing compound metabolic process | neuron projection development | organic substance metabolic process | grooming behavior | pigment metabolic process | animal organ development | forebrain development | hypoxanthine metabolic process | adenine biosynthetic process | IMP biosynthetic process | purine-containing compound salvage | cell activation | dendrite morphogenesis | organonitrogen compound catabolic process | lymphocyte proliferation | ribose phosphate biosynthetic process | cell development | anatomical structure morphogenesis | dendrite development | developmental process | purine nucleobase metabolic process | carbohydrate derivative metabolic process | response to organonitrogen compound | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | response to amphetamine | purine ribonucleotide catabolic process | IMP salvage | immune system process | cellular metabolic process | IMP metabolic process | nucleoside monophosphate biosynthetic process | guanine metabolic process | purine nucleotide catabolic process | multicellular organismal process

GO Cellular Component

cell | cytoplasm | cytosol | intracellular