QuickView for IGF2;jsessionid=6CCE3E786A1BCA8EEBBD350DCA626716;jsessionid=86B04E6417A1904D5F76524FB66E2688 (gene)
- Gene Symbol:
- Igf2
Rattus norvegicus - Full name:
- insulin-like growth factor 2
- Synonyms:
- IGFII, RNIGF2, insulin-like growth factor II, IGF-II, Insulin-like growth factor II (somatomedin A), MSA, insulin-like growth factor II (IGF-II), insulin-like growth factor II isoform 2 variant 4 preprotein, multiplication-stimulating activity, multiplication-stimulating polypeptide
- Genomic Location:
- Chr 1: 202906624-202915231
- Description:
-
a mitogenic growth factor; may have a role in fetal development
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
PBX1_02 , GATA1_03 , MYOD_Q6 , LMO2COM_01 , AREB6_03 , E12_Q6 , E2A_Q2 , MYOD_Q6_01 , ATGTCAC_MIR489 , CAGGTG_E12_Q6
| Transcripts Names |
|---|
| NM_031511 |
| XM_001064965 |
| NM_001190163 |
| NM_001190162 |
| XM_006230664 |
| XM_008760074 |
| XM_006230665 |
GO Molecular Function
protein kinase activator activity | protein serine/threonine kinase activator activity | enzyme activator activity | protein kinase regulator activity | kinase regulator activity | protein-containing complex binding | signaling receptor binding | hormone activity | molecular function regulator | integrin binding | cell adhesion molecule binding | protein binding | insulin receptor binding | receptor regulator activity | kinase activator activity | growth factor activity | receptor ligand activity | insulin-like growth factor receptor binding | enzyme regulator activity
GO Biological Process
response to extracellular stimulus | positive regulation of glycogen biosynthetic process | response to radiation | positive regulation of hormone biosynthetic process | regulation of cell cycle process | protein kinase activator activity | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | protein serine/threonine kinase activator activity | response to nutrient levels | negative regulation of immune system process | positive regulation of cellular component organization | developmental process involved in reproduction | enzyme activator activity | regulation of localization | protein kinase regulator activity | positive regulation of steroid hormone biosynthetic process | regulation of carbohydrate metabolic process | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | response to hormone | insulin receptor signaling pathway via phosphatidylinositol 3-kinase | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | glucose metabolic process | positive regulation of lymphocyte activation | cell differentiation | positive regulation of epithelial cell proliferation | response to drug | regulation of leukocyte mediated cytotoxicity | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | response to antibiotic | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | regulation of steroid hormone biosynthetic process | kinase regulator activity | reproductive system development | response to estradiol | regulation of mitotic nuclear division | female pregnancy | negative regulation of nucleic acid-templated transcription | negative regulation of innate immune response | positive regulation of protein kinase activity | regulation of histone modification | regulation of cell cycle | positive regulation of catalytic activity | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | negative regulation of cellular metabolic process | response to peptide hormone | regulation of cell differentiation | muscle structure development | muscle cell differentiation | regulation of angiogenesis | regulation of protein kinase B signaling | regulation of immune response | regulation of cellular process | positive regulation of insulin receptor signaling pathway | regulation of metabolic process | positive regulation of activated T cell proliferation | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | regulation of cell division | positive regulation of epithelial cell migration | regulation of vasculature development | response to stimulus | positive regulation of vascular endothelial cell proliferation | cellular response to mechanical stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of lipid biosynthetic process | response to peptide | positive regulation of cell-cell adhesion | positive regulation of cell activation | reproduction | response to alcohol | positive regulation of T cell activation | positive regulation of blood vessel endothelial cell migration | hormone activity | regulation of glycogen (starch) synthase activity | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | regulation of cell adhesion | regulation of steroid biosynthetic process | positive regulation of multicellular organism growth | embryo development | regulation of steroid metabolic process | activation of protein kinase activity | molecular function regulator | embryonic placenta development | response to ethanol | regulation of nucleic acid-templated transcription | response to nitrogen compound | cellular response to hormone stimulus | positive regulation of mononuclear cell proliferation | response to nicotine | system development | reproductive process | regulation of signal transduction | positive regulation of organelle organization | multicellular organism development | cellular response to peptide hormone stimulus | regulation of MAPK cascade | learning or memory | cellular response to insulin stimulus | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of hormone levels | wound healing | regulation of T cell activation | negative regulation of natural killer cell mediated cytotoxicity | positive regulation of cell cycle | regulation of activated T cell proliferation | positive regulation of mitotic cell cycle | regulation of gene expression | pancreas development | response to lipid | nervous system process | cellular response to peptide | exocrine pancreas development | insulin receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | monosaccharide metabolic process | small molecule metabolic process | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | regulation of endothelial cell migration | cognition | positive regulation of steroid metabolic process | positive regulation of cell migration | regulation of hormone metabolic process | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | negative regulation of immune response | carbohydrate metabolic process | response to toxic substance | positive regulation of glycogen (starch) synthase activity | positive regulation of cellular response to insulin stimulus | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of lipid biosynthetic process | striated muscle cell differentiation | embryonic morphogenesis | regulation of mitotic cell cycle | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | regulation of innate immune response | digestive system development | regulation of kinase activity | response to wounding | response to mechanical stimulus | positive regulation of steroid biosynthetic process | regulation of intracellular signal transduction | response to insulin | anatomical structure development | kinase activator activity | cell surface receptor signaling pathway | regulation of glucose metabolic process | growth factor activity | metabolic process | positive regulation of glucose metabolic process | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | hexose metabolic process | negative regulation of transcription, DNA-templated | embryonic organ development | behavior | receptor ligand activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of endothelial cell proliferation | regulation of insulin receptor signaling pathway | regulation of cell activation | positive regulation of kinase activity | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | regulation of chromosome organization | positive regulation of endothelial cell migration | positive regulation of MAPK cascade | regulation of natural killer cell mediated cytotoxicity | memory | regulation of epithelial cell migration | positive regulation of carbohydrate metabolic process | regulation of cell communication | regulation of blood vessel endothelial cell migration | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of developmental growth | regulation of T cell proliferation | regulation of epithelial cell proliferation | positive regulation of phosphorylation | enzyme regulator activity | anatomical structure morphogenesis | reproductive structure development | regulation of developmental process | developmental process | regulation of muscle cell differentiation | positive regulation of cell cycle process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | regulation of glycogen biosynthetic process | embryonic placenta morphogenesis | positive regulation of transcription by RNA polymerase II | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of generation of precursor metabolites and energy | in utero embryonic development | regulation of lipid metabolic process | positive regulation of metabolic process | ossification | osteoblast differentiation | positive regulation of lipid metabolic process | regulation of natural killer cell mediated immunity | placenta development | cellular response to organic substance | exocrine system development | positive regulation of cell motility | positive regulation of leukocyte cell-cell adhesion | positive regulation of angiogenesis | regulation of cellular component organization | positive regulation of signaling | positive regulation of mitotic nuclear division | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of glycogen metabolic process | regulation of hormone biosynthetic process | multicellular organismal process | regulation of chromatin organization | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intrinsic component of membrane | extracellular region | extracellular space | membrane
