QuickView for IL-23;jsessionid=BE37678F234FAC655A16542681D32483;jsessionid=ACB2447EB3E558F9014A5327EDD30670 (gene)
- Gene Symbol:
- Il23a
Rattus norvegicus - Full name:
- interleukin 23 subunit alpha
- Synonyms:
- interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, IL-23p19, Interleukin 23, alpha subunit p19, interleukin-23 subunit p19
- Genomic Location:
- Chr 7: 1584112-1586226
- Description:
-
mouse homolog is a pro-inflammatory cytokine; high levels of expression may be associated with rheumatoid arthritis, psoriasis, and multiple sclerosis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity | interleukin-23 receptor binding
GO Biological Process
positive regulation of immune response | positive regulation of cell killing | regulation of leukocyte chemotaxis | regulation of T cell mediated immunity | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to virus | regulation of localization | positive regulation of peptidyl-tyrosine phosphorylation | defense response to other organism | regulation of immune system process | regulation of T-helper 17 type immune response | positive regulation of developmental process | positive regulation of lymphocyte activation | regulation of T cell differentiation | regulation of T cell mediated cytotoxicity | defense response | regulation of leukocyte mediated cytotoxicity | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | defense response to Gram-negative bacterium | positive regulation of T cell differentiation | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | tissue remodeling | positive regulation of immune effector process | positive regulation of memory T cell differentiation | positive regulation of adaptive immune response | positive regulation of T-helper 17 cell differentiation | positive regulation of protein kinase activity | regulation of chemotaxis | positive regulation of defense response to virus by host | regulation of defense response to virus | positive regulation of catalytic activity | regulation of tyrosine phosphorylation of STAT protein | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | positive regulation of natural killer cell proliferation | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | positive regulation of granulocyte macrophage colony-stimulating factor production | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | positive regulation of neutrophil migration | positive regulation of activated T cell proliferation | positive regulation of interferon-gamma production | positive regulation of cellular protein metabolic process | regulation of natural killer cell activation | regulation of neutrophil chemotaxis | T cell activation | positive regulation of tumor necrosis factor production | positive regulation of interleukin-17 production | response to stimulus | positive regulation of osteoclast differentiation | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | regulation of CD4-positive, alpha-beta T cell activation | mononuclear cell proliferation | response to stress | positive regulation of JAK-STAT cascade | positive regulation of lymphocyte proliferation | regulation of activation of Janus kinase activity | regulation of cell proliferation | positive regulation of cell-cell adhesion | positive regulation of cell activation | positive regulation of natural killer cell activation | positive regulation of T cell activation | positive regulation of T-helper 17 cell lineage commitment | positive regulation of RNA biosynthetic process | regulation of cell adhesion | molecular function regulator | regulation of lymphocyte differentiation | regulation of nucleic acid-templated transcription | positive regulation of mononuclear cell proliferation | response to external biotic stimulus | regulation of signal transduction | positive regulation of lymphocyte differentiation | regulation of catalytic activity | regulation of granulocyte chemotaxis | regulation of phosphorylation | regulation of CD4-positive, alpha-beta T cell differentiation | regulation of T cell activation | positive regulation of alpha-beta T cell differentiation | regulation of activated T cell proliferation | regulation of gene expression | positive regulation of chemotaxis | negative regulation of cytokine production | positive regulation of cellular metabolic process | defense response to virus | positive regulation of protein phosphorylation | positive regulation of alpha-beta T cell proliferation | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of STAT cascade | positive regulation of interleukin-12 production | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | regulation of T-helper 17 cell differentiation | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | positive regulation of cell migration | cell proliferation | leukocyte proliferation | positive regulation of NK T cell activation | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | regulation of tumor necrosis factor production | regulation of leukocyte migration | response to bacterium | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of natural killer cell proliferation | positive regulation of NK T cell proliferation | positive regulation of tyrosine phosphorylation of STAT protein | positive regulation of leukocyte chemotaxis | regulation of alpha-beta T cell differentiation | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | lymphocyte activation | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | positive regulation of T-helper cell differentiation | positive regulation of protein modification process | regulation of hemopoiesis | regulation of JAK-STAT cascade | regulation of kinase activity | regulation of intracellular signal transduction | regulation of neutrophil migration | regulation of adaptive immune response | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | positive regulation of neutrophil chemotaxis | receptor ligand activity | immune response | cytokine activity | positive regulation of T-helper 1 type immune response | positive regulation of T cell mediated cytotoxicity | T cell proliferation | regulation of cell activation | positive regulation of leukocyte migration | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of cytokine production | cell activation | positive regulation of T cell mediated immunity | regulation of T-helper cell differentiation | regulation of osteoclast differentiation | lymphocyte proliferation | regulation of cell communication | positive regulation of interleukin-10 production | regulation of transcription, DNA-templated | regulation of T cell proliferation | positive regulation of CD4-positive, alpha-beta T cell differentiation | positive regulation of phosphorylation | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | positive regulation of alpha-beta T cell activation | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of leukocyte mediated cytotoxicity | innate immune response | positive regulation of T-helper 17 type immune response | positive regulation of nucleic acid-templated transcription | positive regulation of granulocyte chemotaxis | positive regulation of transcription by RNA polymerase II | regulation of defense response to virus by host | positive regulation of cell fate commitment | regulation of cell fate commitment | positive regulation of metabolic process | regulation of interferon-gamma production | positive regulation of myeloid leukocyte differentiation | immune system process | positive regulation of cell motility | positive regulation of CD4-positive, alpha-beta T cell activation | positive regulation of leukocyte cell-cell adhesion | regulation of memory T cell differentiation | response to other organism | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | positive regulation of activation of Janus kinase activity | multicellular organismal process | negative regulation of interleukin-10 production | regulation of phosphorus metabolic process
GO Cellular Component
interleukin-23 complex | protein-containing complex | extracellular region | extracellular space
