QuickView for ITGB2;jsessionid=817D123EC00B75996B974487DEFF3F68;jsessionid=491C820179D41DD88DCF852F89492800 (gene)
- Gene Symbol:
- Itgb2
Rattus norvegicus - Full name:
- integrin subunit beta 2
- Synonyms:
- Cd18, integrin beta-2, CD18 leukocyte adhesion molecule, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit), macrophage antigen 1 (mac-1) beta subunit)
- Genomic Location:
- Chr 20: 11446703-11485008
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
kinase binding | peptide binding | opsonin binding | amyloid-beta binding | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | complement binding | signaling receptor binding | complement component C3b binding | amide binding | signaling receptor activity | ICAM-3 receptor activity | protein heterodimerization activity | integrin binding | cell adhesion molecule binding | protein binding | protein dimerization activity | heat shock protein binding
GO Biological Process
positive regulation of immune response | cell motility | phagocytosis, engulfment | regulation of localization | cell-substrate adhesion | positive regulation of DNA-binding transcription factor activity | heterotypic cell-cell adhesion | establishment of localization | regulation of immune system process | regulation of nitric oxide biosynthetic process | integrin-mediated signaling pathway | positive regulation of developmental process | cell differentiation | defense response | epithelial cell migration | membrane organization | regulation of neutrophil degranulation | positive regulation of cellular biosynthetic process | cellular process | localization | positive regulation of immune effector process | positive regulation of reactive oxygen species metabolic process | epithelium migration | macromolecule localization | positive regulation of nitrogen compound metabolic process | granulocyte chemotaxis | tissue development | cellular response to low-density lipoprotein particle stimulus | activated T cell proliferation | regulation of angiogenesis | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | cellular component organization | T cell activation | regulation of vasculature development | response to stimulus | neutrophil chemotaxis | regulation of peptidyl-tyrosine phosphorylation | positive regulation of nitric oxide metabolic process | positive regulation of immune system process | cell adhesion mediated by integrin | mononuclear cell proliferation | response to stress | endothelial cell migration | receptor clustering | positive regulation of cell activation | cellular localization | positive regulation of superoxide anion generation | embryo development | cell chemotaxis | leukocyte migration | regulation of nucleic acid-templated transcription | positive regulation of exocytosis | regulation of neurotransmitter levels | locomotion | response to nitrogen compound | positive regulation of reactive oxygen species biosynthetic process | regulation of superoxide metabolic process | multicellular organism development | cell migration | regulation of phosphorylation | localization within membrane | positive regulation of neutrophil degranulation | regulation of gene expression | protein localization to membrane | positive regulation of secretion | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | amyloid-beta clearance | vesicle-mediated transport | endoderm formation | cell proliferation | leukocyte proliferation | regulation of cellular protein metabolic process | positive regulation of regulated secretory pathway | cell communication | regulation of cellular metabolic process | receptor internalization | inflammatory response | regulation of protein metabolic process | leukocyte chemotaxis | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | cellular response to lipoprotein particle stimulus | embryonic morphogenesis | lymphocyte activation | positive regulation of molecular function | response to organic substance | import into cell | regulation of DNA-binding transcription factor activity | regulation of exocytosis | anatomical structure development | cell surface receptor signaling pathway | leukocyte cell-cell adhesion | metabolic process | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | cellular protein localization | membrane invagination | regulation of vesicle-mediated transport | endocytosis | regulation of secretion | cell adhesion | organic substance metabolic process | T cell proliferation | regulation of cell activation | positive regulation of NF-kappaB transcription factor activity | regulation of phosphate metabolic process | cell-cell adhesion | regulation of regulated secretory pathway | cell activation | regulation of reactive oxygen species biosynthetic process | leukocyte migration involved in inflammatory response | anatomical structure formation involved in morphogenesis | lymphocyte proliferation | natural killer cell activation | signaling | regulation of transcription, DNA-templated | cell-matrix adhesion | protein localization | endodermal cell differentiation | endoderm development | anatomical structure morphogenesis | cellular macromolecule localization | regulation of developmental process | receptor-mediated endocytosis | developmental process | cellular extravasation | regulation of transport | regulation of reactive oxygen species metabolic process | regulation of superoxide anion generation | receptor metabolic process | response to organonitrogen compound | formation of primary germ layer | positive regulation of nitric oxide biosynthetic process | positive regulation of metabolic process | gastrulation | immune system process | cellular metabolic process | ameboidal-type cell migration | neutrophil migration | aging | chemotaxis | phagocytosis | positive regulation of angiogenesis | signal transduction | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | adherens junction | focal adhesion | cell | plasma membrane protein complex | intrinsic component of membrane | integrin complex | cytoplasm | cell-substrate junction | receptor complex | membrane microdomain | protein-containing complex | plasma membrane | membrane raft | cytoplasmic region | integrin alphaL-beta2 complex | integral component of plasma membrane | cell periphery | cell-substrate adherens junction | plasma membrane raft | protein complex involved in cell adhesion | cell surface | intracellular | cell junction | membrane | intrinsic component of plasma membrane
