Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for JMJD6;jsessionid=FE19051AAA64558FB36D3DCFE0483A1E;jsessionid=FE883CA51F890F1F436C27FF8A64F5A5 (gene)


Gene Symbol:
Jmjd6 Mus musculus Mus musculus
Full name:
jumonji domain containing 6
Synonyms:
5730436I23Rik, D11Ertd195e, PSR, PtdSerR, Ptdsr, mKIAA0585, bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, apoptotic cell clearance receptor PtdSerR, histone arginine demethylase JMJD6, jmjC domain-containing protein 6, jumonji domain-containing protein 6, lysyl-hydroxylase JMJD6, peptide-lysine 5-dioxygenase JMJD6, phosphatidylserine receptor
Genomic Location:
Chr 11: 116698746-116704763
Description:
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein functions in differentiation of multiple tissues during development, and in anti-inflammatory cytokine signaling. It was first identified as a putative phosphatidylserine rec...
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

peptidyl-lysine 5-dioxygenase activity | cation binding | nucleic acid binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | iron ion binding | demethylase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | single-stranded RNA binding | signaling receptor activity | identical protein binding | histone demethylase activity | histone demethylase activity (H3-R2 specific) | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | protein dimerization activity | dioxygenase activity | transition metal ion binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | histone demethylase activity (H4-R3 specific) | RNA binding

GO Biological Process

RNA metabolic process | RNA processing | peptidyl-amino acid modification | erythrocyte homeostasis | eye development | establishment of localization | myeloid cell differentiation | histone modification | cell differentiation | respiratory tube development | peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine | peptidyl-lysine 5-dioxygenase activity | blood vessel morphogenesis | regulation of mRNA processing | cellular process | lymphocyte differentiation | localization | chromatin organization | protein demethylation | immune system development | myeloid cell development | cell recognition | regulation of cellular process | leukocyte activation | regulation of metabolic process | regulation of mRNA splicing, via spliceosome | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | urogenital system development | T cell activation | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | sprouting angiogenesis | histone H3-R2 demethylation | response to stimulus | RNA splicing | vasculature development | respiratory system development | demethylase activity | cellular nitrogen compound biosynthetic process | tube morphogenesis | cardiovascular system development | cellular nitrogen compound metabolic process | apoptotic cell clearance | hemopoiesis | protein modification process | mRNA metabolic process | cellular biosynthetic process | kidney development | macromolecule modification | blood vessel development | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | leukocyte differentiation | system development | nitrogen compound metabolic process | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | recognition of apoptotic cell | regulation of gene expression | regulation of nitrogen compound metabolic process | vesicle-mediated transport | histone demethylase activity | homeostasis of number of cells | histone demethylase activity (H3-R2 specific) | biosynthetic process | aromatic compound biosynthetic process | angiogenesis | erythrocyte development | sensory organ development | cell communication | regulation of cellular metabolic process | heart development | homeostatic process | regulation of RNA metabolic process | renal system development | protein hydroxylation | lymphocyte activation | T cell differentiation | histone demethylation | protein metabolic process | T cell differentiation in thymus | retina development in camera-type eye | import into cell | phagocytosis, recognition | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of RNA splicing | histone H4-R3 demethylation | regulation of RNA biosynthetic process | oxidation-reduction process | peptidyl-lysine modification | endocytosis | macrophage activation | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | peptidyl-lysine hydroxylation | dioxygenase activity | transcription, DNA-templated | cell activation | lung development | camera-type eye development | anatomical structure formation involved in morphogenesis | signaling | covalent chromatin modification | regulation of transcription, DNA-templated | cell development | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | developmental process | organelle organization | erythrocyte differentiation | cellular protein modification process | tube development | heterocycle metabolic process | demethylation | chromosome organization | immune system process | cellular metabolic process | mRNA processing | hematopoietic or lymphoid organ development | oxidoreductase activity | histone demethylase activity (H4-R3 specific) | circulatory system development | phagocytosis | signal transduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | plasma membrane | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane