Correlation Engine 2.0
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QuickView for KCNH2;jsessionid=5D45D56F1F0ACC48D2847C38C64EA3A9;jsessionid=77AC816A5A98E6D56D231B2C88C1A074;jsessionid=4AD0AE825E52051F5F37F12012DEEAD1;jsessionid=760538B2840F0E624F38799CBFCBDF28 (gene)


Gene Symbol:
Kcnh2 Mus musculus Mus musculus
Full name:
potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms:
AI326795, ERG1, LQT, Lqt2, M-erg, Merg1, merg1a, merg1b, potassium voltage-gated channel subfamily H member 2, eag-related protein 1, ether-a-go-go-related gene potassium channel 1, ether-a-go-go-related protein 1, voltage-gated potassium channel subunit Kv11.1
Genomic Location:
Chr 5: 23825407-23857422
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
E47_01 AP4_01 IK3_01 CDPCR3HD_01 AP1_Q2 AP4_Q5 MYOD_Q6 AP1_Q4 NF1_Q6 CATRRAGC_UNKNOWN





GO Molecular Function

protein histidine kinase activity | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | voltage-gated ion channel activity | delayed rectifier potassium channel activity | passive transmembrane transporter activity | enzyme binding | inward rectifier potassium channel activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | catalytic activity | phosphorelay sensor kinase activity | protein domain specific binding | ubiquitin-like protein ligase binding | cation transmembrane transporter activity | transporter activity | identical protein binding | ion transmembrane transporter activity | scaffold protein binding | C3HC4-type RING finger domain binding | voltage-gated potassium channel activity | protein binding | protein homodimerization activity | potassium channel activity | ubiquitin protein ligase binding | metal ion transmembrane transporter activity | protein dimerization activity | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | kinase activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of ventricular cardiac muscle cell membrane repolarization | protein histidine kinase activity | heart process | actin filament-based process | intracellular signal transduction | regulation of localization | peptidyl-amino acid modification | establishment of localization | negative regulation of potassium ion transport | negative regulation of cellular process | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | membrane depolarization during action potential | response to drug | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | voltage-gated ion channel activity | negative regulation of potassium ion export | cellular process | delayed rectifier potassium channel activity | localization | passive transmembrane transporter activity | metal ion transport | actin filament-based movement | regulation of cellular process | membrane repolarization during action potential | inward rectifier potassium channel activity | transmembrane transporter activity | heart contraction | ventricular cardiac muscle cell action potential | ligand-gated ion channel activity | cellular component organization | positive regulation of potassium ion transport | actin-mediated cell contraction | muscle contraction | response to stimulus | ion gated channel activity | signal transduction by protein phosphorylation | positive regulation of cation transmembrane transport | regulation of blood circulation | regulation of heart rate | negative regulation of transport | blood circulation | cellular component assembly | negative regulation of potassium ion transmembrane transport | protein modification process | macromolecule modification | negative regulation of transmembrane transport | phosphorelay sensor kinase activity | metal ion homeostasis | regulation of potassium ion transmembrane transport | regulation of membrane potential | nitrogen compound metabolic process | phosphorus metabolic process | protein complex oligomerization | ion transmembrane transport | cation transmembrane transporter activity | monovalent inorganic cation transport | positive regulation of ion transmembrane transport | potassium ion export | cellular potassium ion transport | cardiac muscle cell action potential involved in contraction | ion transmembrane transporter activity | potassium ion transport | negative regulation of ion transmembrane transport | peptidyl-histidine phosphorylation | phosphorylation | negative regulation of ion transport | potassium ion export across plasma membrane | regulation of heart contraction | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | cellular response to drug | cell communication | cardiac muscle cell contraction | potassium ion homeostasis | voltage-gated potassium channel activity | homeostatic process | positive regulation of transport | striated muscle contraction | regulation of potassium ion transport | ventricular cardiac muscle cell membrane repolarization | cation transmembrane transport | potassium channel activity | protein-containing complex assembly | positive regulation of potassium ion transmembrane transport | protein metabolic process | regulation of heart rate by cardiac conduction | metal ion transmembrane transporter activity | membrane repolarization during ventricular cardiac muscle cell action potential | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | metabolic process | chemical homeostasis | membrane depolarization | protein kinase activity | phosphorelay signal transduction system | organic substance metabolic process | positive regulation of ion transport | membrane repolarization during cardiac muscle cell action potential | ion homeostasis | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | membrane repolarization | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | cellular protein metabolic process | protein heterooligomerization | cation transport | channel activity | regulation of ion transport | kinase activity | cellular protein modification process | regulation of transport | cardiac muscle cell action potential | potassium ion transmembrane transport | ion channel activity | ion transport | cardiac muscle contraction | cellular metabolic process | substrate-specific channel activity | regulation of membrane repolarization | muscle system process | signal transduction | cardiac conduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | potassium channel complex | inward rectifier potassium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | protein-containing complex | endomembrane system | plasma membrane | nuclear envelope | perinuclear region of cytoplasm | voltage-gated potassium channel complex | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | cell surface | intracellular | membrane | intrinsic component of plasma membrane