QuickView for KCNH2;jsessionid=7712311E2700F7B2283E61BF6CA16BA7;jsessionid=061B488D0A36F6C388724CC1B87DB1B4 (gene)

GO Molecular Function

protein histidine kinase activity | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | voltage-gated ion channel activity | delayed rectifier potassium channel activity | passive transmembrane transporter activity | enzyme binding | inward rectifier potassium channel activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | catalytic activity | phosphorelay sensor kinase activity | protein domain specific binding | ubiquitin-like protein ligase binding | cation transmembrane transporter activity | transporter activity | identical protein binding | ion transmembrane transporter activity | scaffold protein binding | C3HC4-type RING finger domain binding | voltage-gated potassium channel activity | protein binding | protein homodimerization activity | potassium channel activity | ubiquitin protein ligase binding | metal ion transmembrane transporter activity | protein dimerization activity | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | kinase activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of ventricular cardiac muscle cell membrane repolarization | protein histidine kinase activity | heart process | actin filament-based process | intracellular signal transduction | regulation of localization | peptidyl-amino acid modification | establishment of localization | negative regulation of potassium ion transport | negative regulation of cellular process | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | membrane depolarization during action potential | response to drug | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | voltage-gated ion channel activity | negative regulation of potassium ion export | cellular process | delayed rectifier potassium channel activity | localization | passive transmembrane transporter activity | metal ion transport | actin filament-based movement | regulation of cellular process | membrane repolarization during action potential | inward rectifier potassium channel activity | transmembrane transporter activity | heart contraction | ventricular cardiac muscle cell action potential | ligand-gated ion channel activity | positive regulation of potassium ion transport | actin-mediated cell contraction | muscle contraction | response to stimulus | ion gated channel activity | signal transduction by protein phosphorylation | positive regulation of cation transmembrane transport | regulation of blood circulation | regulation of heart rate | negative regulation of transport | blood circulation | negative regulation of potassium ion transmembrane transport | protein modification process | macromolecule modification | negative regulation of transmembrane transport | phosphorelay sensor kinase activity | metal ion homeostasis | regulation of potassium ion transmembrane transport | regulation of membrane potential | nitrogen compound metabolic process | phosphorus metabolic process | ion transmembrane transport | cation transmembrane transporter activity | monovalent inorganic cation transport | positive regulation of ion transmembrane transport | potassium ion export | cellular potassium ion transport | cardiac muscle cell action potential involved in contraction | ion transmembrane transporter activity | potassium ion transport | negative regulation of ion transmembrane transport | peptidyl-histidine phosphorylation | phosphorylation | negative regulation of ion transport | potassium ion export across plasma membrane | regulation of heart contraction | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | cellular response to drug | cell communication | cardiac muscle cell contraction | potassium ion homeostasis | voltage-gated potassium channel activity | homeostatic process | positive regulation of transport | striated muscle contraction | regulation of potassium ion transport | ventricular cardiac muscle cell membrane repolarization | cation transmembrane transport | potassium channel activity | positive regulation of potassium ion transmembrane transport | protein metabolic process | regulation of heart rate by cardiac conduction | metal ion transmembrane transporter activity | membrane repolarization during ventricular cardiac muscle cell action potential | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | metabolic process | chemical homeostasis | membrane depolarization | protein kinase activity | phosphorelay signal transduction system | organic substance metabolic process | positive regulation of ion transport | membrane repolarization during cardiac muscle cell action potential | ion homeostasis | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | membrane repolarization | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | cellular protein metabolic process | cation transport | channel activity | regulation of ion transport | kinase activity | cellular protein modification process | regulation of transport | cardiac muscle cell action potential | potassium ion transmembrane transport | ion channel activity | ion transport | cardiac muscle contraction | cellular metabolic process | substrate-specific channel activity | regulation of membrane repolarization | muscle system process | signal transduction | cardiac conduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | potassium channel complex | inward rectifier potassium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | protein-containing complex | plasma membrane | perinuclear region of cytoplasm | voltage-gated potassium channel complex | integral component of plasma membrane | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | cell surface | intracellular | membrane | intrinsic component of plasma membrane

PATHWAYS

REACTOME_NEURONAL_SYSTEM | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | REACTOME_POTASSIUM_CHANNELS

PROTEIN FAMILY

PAS domain | Cyclic nucleotide-binding domain | PAS-associated, C-terminal | PAC motif | Potassium channel, voltage-dependent, EAG/ELK/ERG | Potassium channel, voltage-dependent, ERG | Ion transport domain | RmlC-like jelly roll fold | Cyclic nucleotide-binding-like | Voltage-dependent channel domain superfamily | PAS domain superfamily