QuickView for KIT;jsessionid=A48C811DAA86E3121E15DEB8A83E68B9;jsessionid=D2F4016C2F7B11A91B7A04AE9F9B0536 (gene)
- Gene Symbol:
- KIT
Canis lupus familiaris - Full name:
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- Synonyms:
- c-KIT
- Genomic Location:
- Chr 13: 50040811-50122336
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cytokine binding | transmembrane receptor protein tyrosine kinase activity | cation binding | transmembrane signaling receptor activity | enzyme binding | ribonucleotide binding | stem cell factor receptor activity | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | protein homodimerization activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | protease binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
lysosome localization | response to radiation | actin filament-based process | exocytosis | detection of stimulus | response to cytokine | cell motility | regulation of cell morphogenesis | immune response-regulating signaling pathway | glycosphingolipid metabolic process | developmental process involved in reproduction | intracellular signal transduction | ovarian follicle development | positive regulation of DNA-binding transcription factor activity | gonad development | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | female gonad development | peptidyl-amino acid modification | erythrocyte homeostasis | transmembrane receptor protein tyrosine kinase activity | actin cytoskeleton organization | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | response to hormone | myeloid cell differentiation | regulation of cell shape | negative regulation of cellular process | cellular response to stem cell factor stimulus | positive regulation of developmental process | regulation of MAP kinase activity | bone development | cell differentiation | male gamete generation | detection of mechanical stimulus involved in sensory perception | defense response | response to erythropoietin | epithelial cell migration | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | B cell differentiation | sensory perception of mechanical stimulus | intracellular transport | cellular process | secretion | lymphocyte differentiation | leukocyte degranulation | establishment of organelle localization | localization | lymphoid progenitor cell differentiation | reproductive system development | epithelium migration | immune system development | multicellular organismal reproductive process | positive regulation of protein kinase activity | sphingolipid metabolic process | positive regulation of catalytic activity | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | myeloid cell development | establishment of localization in cell | mast cell activation | regulation of cell differentiation | gamete generation | positive regulation of muscle cell differentiation | regulation of immune response | regulation of cellular process | leukocyte activation | hematopoietic stem cell migration | regulation of metabolic process | organelle localization | mast cell chemotaxis | positive regulation of cellular protein metabolic process | stem cell factor receptor activity | cellular component organization | cellular lipid metabolic process | T cell activation | development of primary sexual characteristics | regulation of vasculature development | response to stimulus | lamellipodium assembly | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | response to stress | positive regulation of JAK-STAT cascade | leukocyte activation involved in immune response | germ cell development | regulation of cell proliferation | hematopoietic progenitor cell differentiation | pigment cell differentiation | programmed cell death | development of primary female sexual characteristics | melanocyte adhesion | regulation of developmental pigmentation | reproduction | cellular localization | secretion by cell | positive regulation of protein serine/threonine kinase activity | spermatid differentiation | hemopoiesis | cellular component assembly | protein modification process | mast cell migration | embryo development | macromolecule modification | cell chemotaxis | activation of protein kinase activity | myeloid cell homeostasis | leukocyte migration | regulation of nucleic acid-templated transcription | leukocyte differentiation | detection of abiotic stimulus | locomotion | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | cell migration | regulation of MAPK cascade | phosphorus metabolic process | leukocyte mediated immunity | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | embryonic hemopoiesis | regulation of phosphorylation | regulation of gene expression | nervous system process | myeloid leukocyte differentiation | mast cell degranulation | cell projection assembly | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of smooth muscle cell differentiation | developmental pigmentation | mast cell mediated immunity | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | vesicle-mediated transport | positive regulation of smooth muscle cell differentiation | pigmentation | positive regulation of cell differentiation | homeostasis of number of cells | stem cell differentiation | glycolipid metabolic process | cellular response to cytokine stimulus | B cell activation | regulation of cellular protein metabolic process | phosphorylation | regulated exocytosis | digestive tract development | Kit signaling pathway | cytokine production involved in immune response | megakaryocyte differentiation | programmed cell death involved in cell development | protein phosphorylation | immature B cell differentiation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of tyrosine phosphorylation of STAT protein | inflammatory response | cell activation involved in immune response | sensory perception of sound | myeloid cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | leukocyte chemotaxis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | lymphocyte activation | protein tyrosine kinase activity | positive regulation of molecular function | multicellular organism reproduction | activation of MAPK activity | cytokine production | lamellipodium organization | T cell differentiation | development of primary male sexual characteristics | cellular response to thyroid hormone stimulus | protein metabolic process | positive regulation of protein modification process | response to organic substance | digestive system development | regulation of JAK-STAT cascade | regulation of kinase activity | male sex differentiation | response to mechanical stimulus | detection of stimulus involved in sensory perception | myeloid progenitor cell differentiation | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | membrane lipid metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | embryonic organ development | male gonad development | dendritic cell cytokine production | actin cytoskeleton reorganization | cell adhesion | immune response | protein kinase activity | organic substance metabolic process | cell death | animal organ development | epithelial cell-cell adhesion | positive regulation of kinase activity | regulation of phosphate metabolic process | spermatid development | cytoskeleton organization | detection of mechanical stimulus | cell-cell adhesion | cell activation | positive regulation of MAPK cascade | detection of mechanical stimulus involved in sensory perception of sound | sensory perception | regulation of cell communication | signaling | regulation of transcription, DNA-templated | melanocyte migration | cell development | positive regulation of phosphorylation | cellular protein metabolic process | positive regulation of MAP kinase activity | reproductive structure development | regulation of developmental process | melanocyte differentiation | kinase activity | developmental process | organelle organization | regulation of muscle cell differentiation | erythrocyte differentiation | Fc receptor signaling pathway | spermatogenesis | response to thyroid hormone | cellular protein modification process | tube development | carbohydrate derivative metabolic process | mast cell cytokine production | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | positive regulation of vascular smooth muscle cell differentiation | mast cell differentiation | skeletal system development | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | female sex differentiation | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | sex differentiation | ectopic germ cell programmed cell death | megakaryocyte development | erythropoietin-mediated signaling pathway | negative regulation of cell death | chemotaxis | cellular response to erythropoietin | sexual reproduction | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | mast cell granule | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | cell-cell junction | plasma membrane | vacuole | lytic vacuole | extracellular region | membrane-bounded organelle | organelle | lysosome | extracellular space | cell periphery | cell surface | intracellular | cell junction | membrane
