QuickView for LIF;jsessionid=6C920A1A1DD890D5DEA6382066E8FDD9;jsessionid=08C7F6F892498C490A227E4032541CDE (gene)
- Gene Symbol:
- LIF
Canis lupus familiaris - Full name:
- leukemia inhibitory factor (cholinergic differentiation factor)
- Synonyms:
- N/A
- Genomic Location:
- Chr 26: 26433313-26436800
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
signaling receptor binding | cytokine receptor binding | leukemia inhibitory factor receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity
GO Biological Process
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | regulation of epithelial cell differentiation involved in kidney development | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | negative regulation of MAPK cascade | positive regulation of cellular component organization | regulation of neurogenesis | developmental process involved in reproduction | regulation of cellular localization | intracellular signal transduction | regulation of cell development | regulation of localization | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | regulation of meiotic cell cycle | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | JAK-STAT cascade | respiratory tube development | maternal placenta development | nervous system development | negative regulation of protein phosphorylation | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | regulation of organelle organization | generation of neurons | negative regulation of meiotic cell cycle | positive regulation of cellular biosynthetic process | cellular process | tissue remodeling | negative regulation of signaling | positive regulation of peptidyl-serine phosphorylation | neuron development | reproductive system development | leukemia inhibitory factor signaling pathway | female pregnancy | multicellular organismal reproductive process | stem cell population maintenance | regulation of histone modification | negative regulation of secretion | regulation of cell cycle | regulation of tyrosine phosphorylation of STAT protein | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of hormone secretion | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | muscle structure development | regulation of cellular process | regulation of metabolic process | regulation of nephron tubule epithelial cell differentiation | positive regulation of cellular protein metabolic process | muscle organ morphogenesis | response to stimulus | vasculature development | lung lobe morphogenesis | regulation of cellular protein localization | respiratory system development | regulation of peptidyl-tyrosine phosphorylation | blood vessel remodeling | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidyl-serine phosphorylation of STAT protein | positive regulation of JAK-STAT cascade | trophoblast giant cell differentiation | positive regulation of cellular protein localization | regulation of cell proliferation | regulation of epithelial cell differentiation | regulation of transcription regulatory region DNA binding | reproduction | cardiovascular system development | regulation of histone H3-K27 acetylation | negative regulation of transport | regulation of DNA binding | positive regulation of gliogenesis | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | protein modification process | embryo development | macromolecule modification | negative regulation of ERK1 and ERK2 cascade | molecular function regulator | embryonic placenta development | positive regulation of macrophage differentiation | regulation of nucleic acid-templated transcription | lung alveolus development | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | negative regulation of secretion by cell | negative regulation of phosphate metabolic process | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | negative regulation of meiotic nuclear division | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | regulation of metanephric nephron tubule epithelial cell differentiation | positive regulation of chromosome organization | regulation of gene expression | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | stem cell differentiation | positive regulation of protein localization to nucleus | cell differentiation involved in embryonic placenta development | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | chordate embryonic development | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | lung vasculature development | regulation of RNA metabolic process | positive regulation of protein acetylation | decidualization | neuron differentiation | multicellular organism reproduction | regulation of signaling receptor activity | maternal process involved in female pregnancy | receptor regulator activity | protein metabolic process | positive regulation of protein modification process | regulation of meiotic nuclear division | regulation of hemopoiesis | regulation of JAK-STAT cascade | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | positive regulation of peptidyl-lysine acetylation | negative regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | growth factor activity | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | embryonic organ development | positive regulation of glial cell differentiation | regulation of secretion | receptor ligand activity | immune response | cytokine activity | organic substance metabolic process | maintenance of cell number | animal organ development | positive regulation of histone modification | positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | regulation of chromosome organization | positive regulation of astrocyte differentiation | positive regulation of MAPK cascade | lung development | regulation of peptidyl-serine phosphorylation | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of glial cell differentiation | regulation of cell communication | regulation of gliogenesis | regulation of macrophage differentiation | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | regulation of peptidyl-serine phosphorylation of STAT protein | cell development | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | reproductive structure development | regulation of nervous system development | tyrosine phosphorylation of STAT protein | regulation of developmental process | regulation of RNA polymerase II regulatory region sequence-specific DNA binding | developmental process | cellular protein modification process | positive regulation of epithelial cell differentiation | regulation of histone acetylation | tube development | positive regulation of histone acetylation | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of histone H3-K27 acetylation | positive regulation of kidney development | positive regulation of nucleic acid-templated transcription | lung morphogenesis | positive regulation of transcription by RNA polymerase II | embryo implantation | in utero embryonic development | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | immune system process | lung lobe development | cellular metabolic process | negative regulation of cell cycle process | placenta development | regulation of protein localization | regulation of astrocyte differentiation | spongiotrophoblast layer development | spongiotrophoblast differentiation | circulatory system development | regulation of cellular component organization | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization | regulation of phosphorus metabolic process
GO Cellular Component
cell | cytoplasm | extracellular region | cytosol | intracellular
