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QuickView for MAPK1;jsessionid=CEE42355B31D8C288D6C5C69ABD395FA;jsessionid=4B22FC5C2562272EBE0080E4E592ADE2 (gene)


Gene Symbol:
MAPK1 Canis lupus familiaris Canis lupus familiaris
Full name:
mitogen-activated protein kinase 1
Synonyms:
ERK2
Genomic Location:
Chr 26: 34078000-34197331
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

protein phosphorylated amino acid binding | enzyme binding | phosphotyrosine residue binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | phosphoprotein binding | protein binding | MAP kinase kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | protein serine/threonine/tyrosine kinase activity | drug binding | kinase activity | phosphatase binding | heterocyclic compound binding | small molecule binding

GO Biological Process

cytosine metabolic process | positive regulation of immune response | response to extracellular stimulus | regulation of telomere maintenance via telomerase | positive regulation of macromolecule biosynthetic process | response to nutrient levels | response to cytokine | positive regulation of cellular component organization | immune response-regulating signaling pathway | response to lipopolysaccharide | developmental process involved in reproduction | intracellular signal transduction | positive regulation of telomere capping | peptidyl-amino acid modification | positive regulation of peptidyl-threonine phosphorylation | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | response to dopamine | negative regulation of cellular process | regulation of MAP kinase activity | response to metal ion | cellular response to tumor necrosis factor | cell differentiation | immune response-activating cell surface receptor signaling pathway | respiratory tube development | T cell receptor signaling pathway | nervous system development | cellular response to extracellular stimulus | response to drug | cellular chemical homeostasis | neurogenesis | positive regulation of phosphate metabolic process | regulation of organelle organization | mesenchyme development | positive regulation of cellular biosynthetic process | cellular process | response to exogenous dsRNA | cellular response to granulocyte macrophage colony-stimulating factor stimulus | cellular homeostasis | positive regulation of synaptic transmission | reproductive system development | immune system development | positive regulation of telomerase activity | positive regulation of protein kinase activity | cellular response to starvation | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | tissue development | regulation of cell differentiation | regulation of immune response | regulation of cellular process | cellular response to lipid | regulation of metabolic process | gliogenesis | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | MAPK cascade | cellular response to metal ion | head development | regulation of telomere capping | thyroid gland development | response to stimulus | peptidyl-threonine phosphorylation | thymus development | outer ear morphogenesis | vasculature development | mesenchymal cell development | respiratory system development | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | cardiac neural crest cell development involved in heart development | response to stress | response to starvation | protein serine/threonine kinase activity | reproduction | cellular response to inorganic substance | cardiovascular system development | cellular response to cadmium ion | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | immune response-activating signal transduction | cellular response to organic cyclic compound | ERBB signaling pathway | positive regulation of protein serine/threonine kinase activity | protein modification process | RNA polymerase II CTD heptapeptide repeat kinase activity | modulation of chemical synaptic transmission | embryo development | macromolecule modification | trachea morphogenesis | B cell receptor signaling pathway | activation of protein kinase activity | positive regulation of telomere maintenance via telomere lengthening | embryonic placenta development | blood vessel development | stress-activated protein kinase signaling cascade | response to nitrogen compound | response to nicotine | response to external biotic stimulus | system development | cellular response to nutrient levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | response to granulocyte macrophage colony-stimulating factor | response to dsRNA | mammary gland development | cellular response to DNA damage stimulus | regulation of telomere maintenance | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | cellular response to oxidative stress | regulation of phosphorylation | regulation of ossification | positive regulation of chromosome organization | cellular response to amino acid starvation | cellular response to ammonium ion | regulation of gene expression | cellular response to stress | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of telomerase activity | cellular ion homeostasis | animal organ morphogenesis | response to ammonium ion | regulation of nitrogen compound metabolic process | placenta blood vessel development | enzyme linked receptor protein signaling pathway | small molecule metabolic process | positive regulation of intracellular signal transduction | cardiocyte differentiation | response to oxidative stress | nucleobase-containing small molecule metabolic process | stem cell differentiation | cellular response to cytokine stimulus | cell proliferation | response to cadmium ion | labyrinthine layer development | stress-activated MAPK cascade | regulation of cellular protein metabolic process | glial cell differentiation | phosphorylation | mammary gland epithelial cell proliferation | response to toxic substance | positive regulation of telomere maintenance via telomerase | labyrinthine layer blood vessel development | endocrine system development | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | sensory organ development | trachea formation | cellular response to drug | regulation of telomere maintenance via telomere lengthening | response to bacterium | chordate embryonic development | animal organ formation | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of DNA biosynthetic process | response to catecholamine | astrocyte differentiation | regulation of protein metabolic process | positive regulation of signal transduction | heart development | homeostatic process | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | lipopolysaccharide-mediated signaling pathway | embryonic morphogenesis | positive regulation of molecular function | activation of MAPK activity | embryonic organ morphogenesis | response to monoamine | activation of immune response | protein metabolic process | positive regulation of protein modification process | response to organic substance | gland development | epithelial cell proliferation | regulation of pH | regulation of kinase activity | MAP kinase kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | mesenchymal cell differentiation | embryonic organ development | ear development | chemical homeostasis | trachea development | nucleobase-containing compound metabolic process | protein kinase activity | cellular response to reactive oxygen species | organic substance metabolic process | animal organ development | response to reactive oxygen species | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | regulation of chromosome organization | mammary gland epithelium development | antigen receptor-mediated signaling pathway | Bergmann glial cell differentiation | regulation of cellular pH | positive regulation of MAPK cascade | lung development | response to epidermal growth factor | stem cell development | anatomical structure formation involved in morphogenesis | regulation of cell communication | pyrimidine nucleobase metabolic process | signaling | response to organic cyclic compound | cellular monovalent inorganic cation homeostasis | cell development | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | positive regulation of MAP kinase activity | protein serine/threonine/tyrosine kinase activity | response to biotic stimulus | reproductive structure development | regulation of developmental process | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | kinase activity | developmental process | regulation of DNA biosynthetic process | peptidyl-serine phosphorylation | cellular protein modification process | tube development | response to organonitrogen compound | neural crest cell differentiation | lung morphogenesis | ERK1 and ERK2 cascade | heterocycle metabolic process | response to amino acid starvation | cellular response to dopamine | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | in utero embryonic development | positive regulation of metabolic process | regulation of synaptic plasticity | immune system process | cellular metabolic process | long-term synaptic potentiation | hematopoietic or lymphoid organ development | placenta development | response to tumor necrosis factor | cellular response to organic substance | circulatory system development | ear morphogenesis | neural crest cell development | negative regulation of cell differentiation | regulation of cellular component organization | response to other organism | positive regulation of signaling | cellular response to catecholamine stimulus | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process | face development | regulation of phosphorus metabolic process

GO Cellular Component

cell | pseudopodium | cell projection