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QuickView for MC4R;jsessionid=CC34E127658E683909047F483C7F1DF7;jsessionid=ED5A8B268A43C5C21B3CFA88E5B61180 (gene)


Gene Symbol:
Mc4r Mus musculus Mus musculus
Full name:
melanocortin 4 receptor
Synonyms:
Mc4-r, Pkcp, melanocortin receptor 4
Genomic Location:
Chr 18: 67017359-67020126
Description:
This gene encodes a member of the melanocortin receptor family. Melanocortin receptors are transmembrane G-protein coupled receptors, which respond to small peptide hormones and exhibit diverse functions and tissue type localization. As part of the central nervous melanocortin system, the encoded protein is competitively bound by either melanocyte ...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_016977
Protein Names
Q9EQM7
P56450
Q49NR4



GO Molecular Function

peptide binding | peptide hormone binding | transmembrane signaling receptor activity | enzyme binding | neuropeptide binding | G-protein coupled receptor activity | ubiquitin-like protein ligase binding | amide binding | signaling receptor activity | hormone binding | protein binding | ubiquitin protein ligase binding | melanocyte-stimulating hormone receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity | melanocortin receptor activity

GO Biological Process

response to extracellular stimulus | response to nutrient levels | intracellular signal transduction | hormone secretion | establishment of localization | response to hormone | generation of precursor metabolites and energy | adaptive thermogenesis | regulation of bone remodeling | cellular process | secretion | peptide hormone secretion | localization | protein transport | diet induced thermogenesis | macromolecule localization | response to peptide hormone | regulation of behavior | regulation of cellular process | regulation of metabolic process | G-protein coupled receptor activity | response to stimulus | regulation of feeding behavior | response to peptide | secretion by cell | G-protein coupled receptor signaling pathway | cell-cell signaling | insulin secretion | response to nitrogen compound | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of hormone levels | regulation of grooming behavior | organic substance transport | peptide transport | second-messenger-mediated signaling | peptide secretion | cell communication | cyclic-nucleotide-mediated signaling | response to organic substance | negative regulation of behavior | cAMP-mediated signaling | response to insulin | metabolic process | negative regulation of feeding behavior | oxidation-reduction process | regulation of bone resorption | regulation of tissue remodeling | amide transport | behavior | hormone transport | melanocyte-stimulating hormone receptor activity | establishment of protein localization | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | signaling | feeding behavior | G-protein coupled peptide receptor activity | energy reserve metabolic process | protein localization | positive regulation of tissue remodeling | energy derivation by oxidation of organic compounds | melanocortin receptor activity | positive regulation of bone resorption | response to dietary excess | signal release | response to organonitrogen compound | cellular metabolic process | protein secretion | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane