QuickView for Mash1;jsessionid=C231FF212F2769BB05135E463ABFD2E0;jsessionid=13C2DEAB435DA955D1C0783CD8890A69 (gene)
- Gene Symbol:
- Ascl1
Mus musculus - Full name:
- achaete-scute family bHLH transcription factor 1
- Synonyms:
- AI225900, ASH1, Mash1, bHLHa46, achaete-scute homolog 1, ASH-1, achaete-scute complex homolog 1, achaete-scute complex homolog-like 1, achaete-scute complex-like protein 1, mASH-1, mammalian achaete scute homolog 1
- Genomic Location:
- Chr 10: 86953786-86956405
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | chromatin binding | RNA polymerase II regulatory region DNA binding | E-box binding | bHLH transcription factor binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | brain development | Notch signaling pathway | multicellular organismal movement | sympathetic ganglion development | reflex | positive regulation of macromolecule biosynthetic process | cell motility | regulation of neurogenesis | commitment of neuronal cell to specific neuron type in forebrain | positive regulation of apoptotic process | regulation of cell development | subpallium development | regulation of programmed cell death | neuron migration | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | ventral spinal cord interneuron fate commitment | respiratory tube development | nervous system development | neurogenesis | generation of neurons | pattern specification process | regulation of neuron death | regulation of timing of subpallium neuron differentiation | noradrenergic neuron differentiation | positive regulation of cellular biosynthetic process | cellular process | cell fate specification | musculoskeletal movement | localization | cell maturation | neuron development | central nervous system neuron differentiation | negative regulation of nucleic acid-templated transcription | glandular epithelial cell differentiation | negative regulation of apoptotic process | dorsal spinal cord development | stem cell fate commitment | regulation of cell cycle | lung epithelium development | positive regulation of nitrogen compound metabolic process | forebrain neuron differentiation | negative regulation of cellular metabolic process | neuroblast fate commitment | tissue development | regulation of cell differentiation | autonomic nervous system development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | spinal cord association neuron differentiation | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | pons development | neuroblast fate determination | head development | response to stimulus | respiratory system development | spinal cord oligodendrocyte cell fate specification | oligodendrocyte development | metencephalon development | ganglion development | spinal cord dorsal/ventral patterning | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of epithelial cell differentiation | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | dorsal/ventral pattern formation | parasympathetic nervous system development | neuron fate commitment | regulation of nucleic acid-templated transcription | locomotion | central nervous system neuron development | system development | stomach neuroendocrine cell differentiation | ventral spinal cord development | nitrogen compound metabolic process | regulation of signal transduction | noradrenergic neuron development | multicellular organism development | cell migration | olfactory pit development | neuroblast proliferation | lung neuroendocrine cell differentiation | neuroepithelial cell differentiation | oligodendrocyte cell fate commitment | telencephalon development | positive regulation of cell cycle | regulation of neuron differentiation | regulation of gene expression | stem cell proliferation | positive regulation of cellular metabolic process | positive regulation of Notch signaling pathway | enteric nervous system development | lung secretory cell differentiation | regulation of nitrogen compound metabolic process | nose development | regulation of Notch signaling pathway | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of cell differentiation | stem cell differentiation | cell proliferation | biosynthetic process | aromatic compound biosynthetic process | glial cell differentiation | hindbrain development | digestive tract development | spinal cord oligodendrocyte cell differentiation | positive regulation of neuron death | endocrine system development | sensory organ development | regulation of timing of cell differentiation | cell communication | ventral spinal cord interneuron differentiation | regulation of cellular metabolic process | sympathetic nervous system development | regulation of neuron apoptotic process | positive regulation of signal transduction | positive regulation of cell proliferation | neuroendocrine cell differentiation | forebrain neuron fate commitment | regulation of RNA metabolic process | cerebral cortex development | cell fate commitment involved in pattern specification | regulation of mitotic cell cycle | lung epithelial cell differentiation | neuron differentiation | DNA-binding transcription factor activity | regionalization | gland development | digestive system development | musculoskeletal movement, spinal reflex action | subpallium neuron fate commitment | noradrenergic neuron fate commitment | oligodendrocyte cell fate specification | positive regulation of neuron apoptotic process | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | metabolic process | positive regulation of cell development | cell fate commitment | carotid body glomus cell differentiation | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | adrenal gland development | oligodendrocyte differentiation | stem cell fate determination | spinal cord patterning | forebrain generation of neurons | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | negative regulation of neuron differentiation | pallium development | gene expression | positive regulation of programmed cell death | neural precursor cell proliferation | transcription, DNA-templated | lung development | cell differentiation in spinal cord | regulation of cell communication | signaling | regulation of transcription, DNA-templated | glial cell development | glial cell fate commitment | cell development | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | positive regulation of neural precursor cell proliferation | developmental process | lung cell differentiation | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cell fate determination | regulation of development, heterochronic | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | vestibular nucleus development | central nervous system development | spinal cord development | positive regulation of metabolic process | positive regulation of neuron differentiation | cellular metabolic process | regulation of cell death | adrenal chromaffin cell differentiation | negative regulation of cell death | negative regulation of cell development | neuron fate specification | neuroblast differentiation | negative regulation of cell differentiation | regulation of timing of neuron differentiation | positive regulation of signaling | neural nucleus development | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | somatodendritic compartment | RNA polymerase II transcription factor complex | cell body | cell | neuronal cell body | transcription factor complex | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | intracellular
