QuickView for Mfn2;jsessionid=752A96ED3F94B6F36106787986108EDE;jsessionid=F16D1E2B70CDABB62DB6F3D247736994 (gene)
- Gene Symbol:
- Mfn2
Mus musculus - Full name:
- mitofusin 2
- Synonyms:
- D630023P19Rik, Fzo, mitofusin-2, HSG protein, hypertension related protein 1, mitochondrial assembly regulatory factor, transmembrane GTPase MFN2
- Genomic Location:
- Chr 4: 147247704-147278928
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
guanyl ribonucleotide binding | proteoglycan binding | GTPase binding | ribonucleoside binding | enzyme binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | Ras GTPase binding | catalytic activity | ubiquitin-like protein ligase binding | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | ubiquitin protein ligase binding | protein dimerization activity | GTP binding | hydrolase activity, acting on acid anhydrides | small GTPase binding | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding
GO Biological Process
positive regulation of smooth muscle cell proliferation | blastocyst formation | positive regulation of cellular component organization | positive regulation of apoptotic process | protein localization to mitochondrion | organelle fusion | macroautophagy | regulation of programmed cell death | eye development | establishment of localization | regulation of autophagy | negative regulation of cellular process | membrane fusion | regulation of organelle organization | membrane organization | intracellular transport | positive regulation of vascular smooth muscle cell proliferation | cellular process | localization | protein transport | mitochondrial fusion | negative regulation of signaling | parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | establishment of protein localization to mitochondrion | macromolecule localization | positive regulation of muscle cell apoptotic process | establishment of localization in cell | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organelle localization | response to topologically incorrect protein | cellular component organization | positive regulation of autophagy of mitochondrion | response to stimulus | positive regulation of cold-induced thermogenesis | positive regulation of smooth muscle cell apoptotic process | response to stress | intracellular protein transport | regulation of cell proliferation | programmed cell death | cellular localization | positive regulation of mitophagy in response to mitochondrial depolarization | regulation of macroautophagy | cellular component assembly | embryo development | mitochondrion organization | positive regulation of mitochondrion organization | apoptotic process | organelle assembly | system development | regulation of signal transduction | positive regulation of organelle organization | autophagosome organization | multicellular organism development | regulation of small GTPase mediated signal transduction | organic substance transport | cellular response to stress | positive regulation of cellular metabolic process | animal organ morphogenesis | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | negative regulation of smooth muscle cell proliferation | mitochondrial transport | peptide transport | regulation of smooth muscle cell apoptotic process | protein localization to organelle | mitochondrion localization | sensory organ development | vacuole organization | autophagy | regulation of mitochondrion organization | mitochondrial membrane organization | regulation of muscle cell apoptotic process | chordate embryonic development | regulation of cellular metabolic process | eye morphogenesis | positive regulation of cell proliferation | embryo development ending in birth or egg hatching | regulation of autophagy of mitochondrion | response to organic substance | autophagosome assembly | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | establishment of protein localization to organelle | anatomical structure development | metabolic process | cellular protein localization | amide transport | positive regulation of cell death | cell death | animal organ development | negative regulation of small GTPase mediated signal transduction | negative regulation of Ras protein signal transduction | positive regulation of programmed cell death | positive regulation of autophagy | establishment of protein localization | blastocyst development | positive regulation of macroautophagy | protein localization to phagophore assembly site | camera-type eye development | anatomical structure formation involved in morphogenesis | regulation of cell communication | response to mitochondrial depolarisation | negative regulation of signal transduction | protein localization | response to unfolded protein | regulation of Ras protein signal transduction | anatomical structure morphogenesis | cellular macromolecule localization | camera-type eye morphogenesis | protein targeting to mitochondrion | developmental process | organelle organization | positive regulation of mitophagy | negative regulation of cell proliferation | positive regulation of vascular associated smooth muscle cell apoptotic process | in utero embryonic development | positive regulation of metabolic process | protein targeting | cellular metabolic process | regulation of cell death | regulation of smooth muscle cell proliferation | regulation of cellular component organization | regulation of signaling | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | microtubule cytoskeleton | mitochondrion | intrinsic component of mitochondrial outer membrane | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | outer membrane | mitochondrial membrane | cytosol | cytoskeleton | intracellular | membrane
