QuickView for Myd88;jsessionid=3B6B586DC247F1A5FF32B8E3BE58303A;jsessionid=0895EF66641568F9B0723A153C028B93 (gene)
- Gene Symbol:
- Myd88
Rattus norvegicus - Full name:
- myeloid differentiation primary response 88
- Synonyms:
- myeloid differentiation primary response protein MyD88, myeloid differentiation primary response gene 88
- Genomic Location:
- Chr 8: 124299729-124303798
- Description:
-
an adaptor protein which binds toll-like receptors and links them to other downstream signalling molecules
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
GO Molecular Function
protein self-association | signaling receptor binding | cytokine receptor binding | Toll-like receptor binding | protein domain specific binding | identical protein binding | TIR domain binding | protein binding | Toll binding | interleukin-1 receptor binding | growth factor receptor binding
GO Biological Process
positive regulation of immune response | positive regulation of smooth muscle cell proliferation | adaptive immune response | positive regulation of macromolecule biosynthetic process | response to virus | response to cytokine | response to interleukin-1 | immune response-regulating signaling pathway | response to lipopolysaccharide | RNA stabilization | intracellular signal transduction | endothelial cell development | regulation of localization | positive regulation of DNA-binding transcription factor activity | cellular response to type I interferon | defense response to other organism | regulation of immune system process | regulation of chemokine (C-X-C motif) ligand 1 production | negative regulation of cellular process | mRNA stabilization | positive regulation of lymphocyte activation | cell differentiation | endothelial cell differentiation | negative regulation of growth of symbiont involved in interaction with host | defense response | positive regulation of phosphate metabolic process | innate immune response-activating signal transduction | positive regulation of cellular biosynthetic process | cellular process | toll-like receptor signaling pathway | response to type I interferon | regulation of cytokine biosynthetic process | regulation of cell motility | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | cellular response to oxidised low-density lipoprotein particle stimulus | regulation of mRNA stability | regulation of immune response | regulation of cellular process | cellular response to lipid | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | cellular response to molecule of bacterial origin | induced systemic resistance | positive regulation of cellular protein metabolic process | epithelium development | MAPK cascade | positive regulation of tumor necrosis factor production | positive regulation of interleukin-17 production | regulation of type I interferon production | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | cellular response to mechanical stimulus | JNK cascade | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | positive regulation of chemokine biosynthetic process | positive regulation of lymphocyte proliferation | posttranscriptional regulation of gene expression | regulation of cell proliferation | regulation of chemokine (C-X-C motif) ligand 2 production | epithelial cell development | Toll signaling pathway | programmed cell death | positive regulation of cytokine biosynthetic process | positive regulation of cell activation | activation of innate immune response | response to molecule of bacterial origin | immune response-activating signal transduction | negative regulation of metabolic process | protein modification process | macromolecule modification | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | positive regulation of mononuclear cell proliferation | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | endothelium development | pattern recognition receptor signaling pathway | negative regulation of growth | regulation of MAPK cascade | phosphorus metabolic process | positive regulation of inflammatory response | type I interferon production | leukocyte mediated immunity | regulation of phosphorylation | regulation of gene expression | cellular response to stress | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | establishment of endothelial barrier | response to peptidoglycan | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of JNK cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of RNA stability | regulation of cellular component movement | positive regulation of cytokine production involved in inflammatory response | cellular response to cytokine stimulus | regulation of cytokine production involved in inflammatory response | positive regulation of interleukin-23 production | biosynthetic process | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | positive regulation of chemokine production | regulation of interleukin-23 production | protein phosphorylation | regulation of tumor necrosis factor production | regulation of leukocyte migration | phosphate-containing compound metabolic process | response to bacterium | response to fungus | cell communication | regulation of cellular metabolic process | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | positive regulation of cell proliferation | regulation of protein phosphorylation | establishment of endothelial intestinal barrier | regulation of locomotion | regulation of RNA metabolic process | lipopolysaccharide-mediated signaling pathway | cellular response to lipoprotein particle stimulus | 3'-UTR-mediated mRNA stabilization | negative regulation of mRNA catabolic process | positive regulation of molecular function | cytokine production | activation of immune response | response to molecule of fungal origin | protein metabolic process | positive regulation of protein modification process | regulation of growth | response to organic substance | regulation of innate immune response | response to mechanical stimulus | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | negative regulation of growth of symbiont in host | regulation of neutrophil migration | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | type I interferon biosynthetic process | positive regulation of interleukin-6 production | immune response | organic substance metabolic process | cell death | regulation of mRNA catabolic process | regulation of cell activation | positive regulation of NF-kappaB transcription factor activity | regulation of phosphate metabolic process | positive regulation of cytokine production | regulation of JNK cascade | positive regulation of MAPK cascade | type I interferon signaling pathway | defense response to Gram-positive bacterium | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | cell development | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | response to biotic stimulus | B cell mediated immunity | cytokine biosynthetic process | developmental process | cellular protein modification process | regulation of chemokine production | innate immune response | MyD88-dependent toll-like receptor signaling pathway | response to organonitrogen compound | epithelial cell differentiation | cytokine metabolic process | positive regulation of metabolic process | immunoglobulin mediated immune response | immune system process | cellular metabolic process | cellular response to organic substance | regulation of smooth muscle cell proliferation | positive regulation of type I interferon production | regulation of interleukin-6 production | regulation of inflammatory response | regulation of I-kappaB kinase/NF-kappaB signaling | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | synapse | cell | cytoplasm | intracellular organelle | protein-containing complex | postsynapse | plasma membrane | postsynaptic density | asymmetric synapse | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cell periphery | cytosol | intracellular | membrane
