QuickView for NBN;jsessionid=CD74FC213603C0F981022153C60E95B5;jsessionid=2C1B3D5E5F64117B4C66E8528063E49B;jsessionid=E2E3422E16403F9EDF0189259CBA0E51 (gene)
- Gene Symbol:
- NBN
Gallus gallus - Full name:
- nibrin
- Synonyms:
- NBS1
- Genomic Location:
- Chr 2: 129112204-129137151
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
GO Molecular Function
nucleic acid binding | ATP-dependent DNA helicase activity | hydrolase activity | ATPase activity | pyrophosphatase activity | catalytic activity | protein N-terminus binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | damaged DNA binding | ATP-dependent helicase activity | organic cyclic compound binding | DNA helicase activity | protein binding | transcription factor binding | hydrolase activity, acting on acid anhydrides | DNA-dependent ATPase activity | helicase activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO Biological Process
double-strand break repair | adaptive immune response | regulation of cell cycle process | telomere maintenance | positive regulation of cellular component organization | intracellular signal transduction | negative regulation of cellular process | telomere capping | positive regulation of phosphate metabolic process | regulation of organelle organization | negative regulation of DNA metabolic process | neuromuscular process controlling balance | cellular process | mitotic DNA integrity checkpoint | immune system development | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | DNA geometric change | anatomical structure homeostasis | t-circle formation | intrinsic apoptotic signaling pathway | regulation of cellular process | leukocyte activation | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | cellular component organization | ATP-dependent DNA helicase activity | regulation of telomere capping | response to stimulus | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | response to stress | negative regulation of G2/M transition of mitotic cell cycle | leukocyte activation involved in immune response | regulation of cell proliferation | mitotic G2 DNA damage checkpoint | regulation of cell cycle phase transition | programmed cell death | reproduction | cellular nitrogen compound metabolic process | telomere organization | negative regulation of metabolic process | cellular component assembly | DNA recombination | DNA repair | apoptotic process | regulation of cell cycle G2/M phase transition | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | system development | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | positive regulation of organelle organization | double-strand break repair via homologous recombination | mitotic DNA damage checkpoint | multicellular organism development | negative regulation of cell cycle G2/M phase transition | cellular response to DNA damage stimulus | regulation of telomere maintenance | leukocyte mediated immunity | regulation of catalytic activity | regulation of phosphorylation | somatic recombination of immunoglobulin gene segments | positive regulation of chromosome organization | signal transduction in response to DNA damage | cellular response to stress | nervous system process | cell cycle | regulation of protein autophosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | B cell activation | cell proliferation | regulation of cellular protein metabolic process | DNA duplex unwinding | DNA strand elongation | cell communication | regulation of cellular metabolic process | cell activation involved in immune response | regulation of protein metabolic process | homeostatic process | regulation of protein phosphorylation | negative regulation of telomere maintenance | apoptotic signaling pathway | regulation of mitotic cell cycle | DNA helicase activity | lymphocyte activation | positive regulation of molecular function | mitotic G2/M transition checkpoint | regulation of fibroblast proliferation | positive regulation of protein modification process | telomeric 3' overhang formation | regulation of kinase activity | DNA metabolic process | anatomical structure development | mitotic cell cycle | metabolic process | immunoglobulin production involved in immunoglobulin mediated immune response | immunoglobulin production | somatic diversification of immunoglobulins | negative regulation of mitotic cell cycle | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of chromosome organization | cell activation | negative regulation of cell cycle | somatic recombination of immunoglobulin genes involved in immune response | meiotic cell cycle | negative regulation of chromosome organization | signaling | neuromuscular process | B cell activation involved in immune response | positive regulation of phosphorylation | somatic cell DNA recombination | telomere maintenance via telomere trimming | B cell mediated immunity | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | negative regulation of telomere capping | recombinational repair | developmental process | organelle organization | positive regulation of protein autophosphorylation | DNA conformation change | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | isotype switching | immunoglobulin mediated immune response | immune system process | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | regulation of cellular component organization | signal transduction | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
nuclear inclusion body | site of DNA damage | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | replication fork | nucleolus | intracellular organelle | nuclear body | inclusion body | protein-containing complex | PML body | nucleoplasm | nuclear chromosome | chromosome, telomeric region | site of double-strand break | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromosome, telomeric region | intracellular | Mre11 complex
