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QuickView for NPY;jsessionid=FBA10F08AE6B519100C5BDC18C041173;jsessionid=8C81241E109E7514E66B41D8F82FC784 (gene)


Gene Symbol:
Npy Rattus norvegicus Rattus norvegicus
Full name:
neuropeptide Y
Synonyms:
NPY02, RATNPY, RATNPY02, pro-neuropeptide Y
Genomic Location:
Chr 4: 78038013-78045187
Description:
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. Studies in the rat model of depression (Flinders Sensitive Line) show that this gene is downregulated in t...
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012614
Protein Names
P07808
F2W8A6



GO Molecular Function

neuropeptide Y receptor binding | signaling receptor binding | hormone activity | neuropeptide receptor binding | molecular function regulator | protein binding | receptor regulator activity | neuropeptide hormone activity | G-protein coupled receptor binding | receptor ligand activity

GO Biological Process

response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | brain development | response to radiation | response to nutrient levels | negative regulation of immune system process | positive regulation of behavior | regulation of immune system process | negative regulation of neuron death | negative regulation of cellular process | cell differentiation | nervous system development | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | generation of neurons | regulation of neuron death | positive regulation of eating behavior | cellular process | neuropeptide signaling pathway | negative regulation of inflammatory response | chemical synaptic transmission | neuron development | positive regulation of reactive oxygen species metabolic process | central nervous system neuron differentiation | positive regulation of nitrogen compound metabolic process | regulation of appetite | regulation of behavior | negative regulation of acute inflammatory response | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | head development | response to stimulus | regulation of feeding behavior | positive regulation of nitric oxide metabolic process | positive regulation of protein metabolic process | positive regulation of feeding behavior | regulation of cell proliferation | regulation of dopamine metabolic process | hormone activity | blood circulation | G-protein coupled receptor signaling pathway | regulation of cell adhesion | cell-cell signaling | molecular function regulator | negative regulation of blood pressure | regulation of catecholamine metabolic process | regulation of neurotransmitter levels | central nervous system neuron development | response to light stimulus | system development | regulation of signal transduction | positive regulation of response to food | multicellular organism development | regulation of MAPK cascade | regulation of phosphorylation | negative regulation of acute inflammatory response to antigenic stimulus | regulation of acute inflammatory response | telencephalon development | nervous system process | regulation of response to food | regulation of blood pressure | synaptic signaling | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of dopamine metabolic process | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | positive regulation of intracellular signal transduction | positive regulation of appetite | regulation of cellular protein metabolic process | negative regulation of immune response | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | cerebral cortex development | neuron differentiation | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | regulation of eating behavior | adult feeding behavior | regulation of intracellular signal transduction | anatomical structure development | neuropeptide hormone activity | cell projection organization | monocyte activation | behavior | receptor ligand activity | neuron projection development | animal organ development | forebrain development | positive regulation of cell-substrate adhesion | pallium development | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | cell activation | positive regulation of MAPK cascade | adult behavior | sensory perception | regulation of cell communication | signaling | feeding behavior | cell development | sensory perception of chemical stimulus | positive regulation of phosphorylation | regulation of nerve growth factor production | developmental process | sensory perception of taste | regulation of reactive oxygen species metabolic process | photoperiodism | central nervous system development | positive regulation of metabolic process | immune system process | short-day photoperiodism | regulation of cell death | negative regulation of inflammatory response to antigenic stimulus | negative regulation of cell death | regulation of inflammatory response | aging | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | distal axon | terminal bouton | cytoplasm | intracellular organelle | presynapse | Golgi apparatus | cell projection | endomembrane system | perikaryon | perinuclear region of cytoplasm | extracellular region | membrane-bounded organelle | organelle | axon terminus | extracellular space | axon | neuron projection terminus | intracellular