Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for NR1I2;jsessionid=9D9492A0A346BB4BFF40F2B9F5FE2E64;jsessionid=B8CFA00A662FD84B9544D59D8E8E1234 (gene)


Gene Symbol:
Nr1i2 Rattus norvegicus Rattus norvegicus
Full name:
nuclear receptor subfamily 1, group I, member 2
Synonyms:
PXR, nuclear receptor subfamily 1 group I member 2, nuclear receptor subfamily 1, group 1, member 2, orphan nuclear receptor PXR, pregnane X receptor (nuclear receptor sub family 1, group I, member 2)
Genomic Location:
Chr 11: 64239946-64276130
Description:
involved in the induction of cytochrome P4503A (CYP3A)
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Canis lupus familiaris Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_052980
Protein Names
Q9R1A7



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | nucleic acid binding | steroid hormone receptor activity | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | nuclear receptor transcription coactivator activity | RNA polymerase II regulatory region sequence-specific DNA binding | transition metal ion binding | drug binding | transcription coregulator activity | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | establishment of localization | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | response to drug | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | nuclear receptor activity | localization | transcription factor activity, direct ligand regulated sequence-specific DNA binding | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | drug export | response to stimulus | cellular response to xenobiotic stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | drug catabolic process | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | exogenous drug catabolic process | biosynthetic process | aromatic compound biosynthetic process | response to xenobiotic stimulus | cell communication | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | drug metabolic process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to organic substance | xenobiotic transport | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nuclear receptor transcription coactivator activity | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | drug transport | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular macromolecule biosynthetic process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | nuclear body | intermediate filament cytoskeleton | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoskeleton | intracellular