QuickView for NT-3;jsessionid=76E40324846337DD1D6F94B607935F11;jsessionid=835D14C4ED326F19F96CA8092BD92B6F (gene)

Gene Symbol:

Ntf3 Mus musculus

Full name:

neurotrophin 3

Synonyms:

AI316846, AI835689, HDNF, NGF-2, Nt3, Ntf-3, neurotrophin-3, nerve growth factor 2, neurotrophic factor

Genomic Location:

Chr 6: 126051430-126114939

Description:

This gene encodes a member of the neurotrophins that have a wide variety of functions in both neural and non-neural tissues. The encoded preproprotein undergoes proteolytic processing to generate a noncovalently linked homodimeric mature protein that can bind to the transmembrane receptor tyrosine kinases to initiate a series of signaling events. M...

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This gene encodes a member of the neurotrophins that have a wide variety of functions in both neural and non-neural tissues. The encoded preproprotein undergoes proteolytic processing to generate a noncovalently linked homodimeric mature protein that can bind to the transmembrane receptor tyrosine kinases to initiate a series of signaling events. Mice lacking the encoded protein exhibit severe defects in the peripheral nervous system including a complete lack of spinal proprioceptive afferents and their peripheral sense organs.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HOX13_01 ,  SOX5_01 ,  TAL1ALPHAE47_01 ,  HFH1_01 ,  BRN2_01 ,  RORA1_01 ,  SRY_02 ,  FREAC7_01 ,  HFH8_01 ,  AREB6_02 ,  FOXJ2_01 ,  CCTNTMAGA_UNKNOWN ,  POU6F1_01 ,  TBP_01 ,  ERR1_Q2 ,  HNF6_Q6 ,  LBP1_Q6 ,  TEF_Q6 ,  SF1_Q6 ,  CDX2_Q5 ,  HNF1_Q6 ,  FOX_Q2 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  ATGTAGC_MIR221_MIR222 ,  TATTATA_MIR374 ,  ATATGCA_MIR448 ,  ATAAGCT_MIR21 ,  RRAGTTGT_UNKNOWN ,  WGTTNNNNNAAA_UNKNOWN ,  CAGCTG_AP4_Q5 ,  CAGGTG_E12_Q6 ,  TGACCTY_ERR1_Q2 ,  TTGTTT_FOXO4_01 ,  RTAAACA_FREAC2_01 ,  GATAAGR_GATA_C ,  CTTTGA_LEF1_Q2 ,  TGGAAA_NFAT_Q4_01 ,  TGACCTTG_SF1_Q6 ,  TATAAA_TATA_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-21 ,  Predicted Gene Targets for miR-221 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-410

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