QuickView for NT5E;jsessionid=ACBDF7D07CA0D7963A87E16CA31FD4B2;jsessionid=19FD66A1597D56F6B024F7BDC5400535 (gene)

Gene Symbol:

Nt5e Mus musculus

Full name:

5' nucleotidase, ecto

Synonyms:

2210401F01Rik, 5'-NT, AI447961, CD73, NT, Nt5, eNT, 5'-nucleotidase, ecto-5'-nucleotidase

Genomic Location:

Chr 9: 88222478-88266927

Description:

This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a sig...

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This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a significantly reduced fall in stop flow pressure and superficial nephron glomerular filtration rate in response to a saturating increase of tubular perfusion flow.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  AAGTCCA_MIR422B_MIR422A

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-378*

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