QuickView for OCP2;jsessionid=DABD7253237E15BD388821519DB5122F;jsessionid=968EAE4CE879ACED2A3874CD761694FE (gene)
- Gene Symbol:
- SKP1
Saccharomyces cerevisiae - Full name:
- Evolutionarily conserved kinetochore protein that is part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase
- Synonyms:
- MGO1, SKP1, Skp1, SKP1, YDR328C
- Genomic Location:
- Chr IV: 1125429-1126013
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
sequence-specific DNA binding | nucleic acid binding | catalytic activity | ubiquitin-like protein transferase activity | DNA binding | sequence-specific double-stranded DNA binding | ubiquitin protein ligase activity | organic cyclic compound binding | protein binding | double-stranded DNA binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | DNA replication origin binding | heterocyclic compound binding
GO Biological Process
regulation of cell cycle process | vacuolar acidification | proteolysis | negative regulation of cellular process | cellular chemical homeostasis | regulation of organelle organization | cellular process | septin ring organization | organic substance catabolic process | cellular homeostasis | proteolysis involved in cellular protein catabolic process | regulation of exit from mitosis | regulation of mitotic nuclear division | regulation of cell cycle | negative regulation of cellular metabolic process | kinetochore organization | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | cellular component organization | pH reduction | regulation of mitotic cell cycle phase transition | intracellular pH reduction | posttranscriptional regulation of gene expression | protein neddylation | regulation of cell cycle phase transition | protein-DNA complex assembly | exit from mitosis | cellular protein catabolic process | proteasomal protein catabolic process | cell cycle G1/S phase transition | negative regulation of metabolic process | cellular component assembly | protein modification process | macromolecule modification | septin cytoskeleton organization | kinetochore assembly | organelle assembly | nitrogen compound metabolic process | regulation of gene expression | centromere complex assembly | cell cycle | protein catabolic process | cellular ion homeostasis | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | ubiquitin protein ligase activity | regulation of cellular protein metabolic process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | G2/M transition of mitotic cell cycle | cellular protein-containing complex assembly | mitotic cell cycle phase transition | cation homeostasis | cellular cation homeostasis | regulation of cellular metabolic process | regulation of intracellular pH | regulation of protein metabolic process | cell cycle G2/M phase transition | homeostatic process | G1/S transition of mitotic cell cycle | proteasome-mediated ubiquitin-dependent protein catabolic process | regulation of mitotic cell cycle | protein-containing complex assembly | protein metabolic process | protein ubiquitination | regulation of pH | cellular macromolecule catabolic process | mitotic cell cycle | nuclear division | metabolic process | ubiquitin-protein transferase activity | chemical homeostasis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | ion homeostasis | protein modification by small protein conjugation or removal | cytoskeleton organization | mitotic nuclear division | negative regulation of translation | regulation of cellular pH | regulation of cytoplasmic translation | ubiquitin-dependent protein catabolic process | negative regulation of protein metabolic process | organonitrogen compound catabolic process | cellular monovalent inorganic cation homeostasis | cellular protein metabolic process | organelle organization | cellular protein modification process | cell cycle phase transition | chromosome organization | negative regulation of cytoplasmic translation | cellular metabolic process | modification-dependent protein catabolic process | regulation of translation | septin ring assembly | regulation of cellular component organization | macromolecule metabolic process
GO Cellular Component
CBF3 complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | chromosome, centromeric region | RAVE complex | condensed chromosome, centromeric region | cell | kinetochore | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | transferase complex | condensed chromosome kinetochore | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | SCF ubiquitin ligase complex | intracellular | condensed chromosome
