QuickView for Osteoprotegerin;jsessionid=19FA951088EFF319C1059AE8A2F154AA;jsessionid=66851D3F4C259889F82B6D2480F7A93D (gene)
- Gene Symbol:
- Tnfrsf11b
Rattus norvegicus - Full name:
- TNF receptor superfamily member 11B
- Synonyms:
- Opg, tumor necrosis factor receptor superfamily member 11B, Osteoprotegerin
- Genomic Location:
- Chr 7: 90606424-90634431
- Description:
-
plays a role in the negative regulation of bone resorption by inhibiting formation of osteoclasts
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
signaling receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity
GO Biological Process
response to extracellular stimulus | response to nutrient levels | extracellular structure organization | response to cytokine | response to metal ion | cellular response to tumor necrosis factor | negative regulation of tissue remodeling | response to drug | regulation of bone remodeling | cellular process | response to magnesium ion | response to inorganic substance | regulation of cellular process | regulation of odontogenesis of dentin-containing tooth | negative regulation of bone resorption | cellular component organization | response to stimulus | extracellular matrix organization | regulation of odontogenesis | molecular function regulator | regulation of signal transduction | cytokine-mediated signaling pathway | response to nutrient | cellular response to cytokine stimulus | response to estrogen | cell communication | regulation of signaling receptor activity | receptor regulator activity | response to organic substance | regulation of animal organ morphogenesis | negative regulation of odontogenesis of dentin-containing tooth | cell surface receptor signaling pathway | regulation of bone resorption | regulation of tissue remodeling | receptor ligand activity | cytokine activity | tumor necrosis factor-mediated signaling pathway | negative regulation of odontogenesis | regulation of cell communication | response to arsenic-containing substance | signaling | regulation of developmental process | negative regulation of bone remodeling | response to tumor necrosis factor | cellular response to organic substance | signal transduction | regulation of signaling
GO Cellular Component
extracellular matrix | extracellular region | extracellular space
