Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for PBX1;jsessionid=5F7715E1237AC1CF6D6630B9A8F1BD6D;jsessionid=B65E9C181A8EDCAC6B370704C2198C58 (gene)


Gene Symbol:
Pbx1 Mus musculus Mus musculus
Full name:
pre B cell leukemia homeobox 1
Synonyms:
2310056B04Rik, D230003C07Rik, Pbx-1, pre-B-cell leukemia transcription factor 1, homeobox protein PBX1
Genomic Location:
Chr 1: 170049495-170362389
Description:
This gene encodes a homeobox protein that belongs to the three-amino-acid loop extension/Pre-B cell leukemia transcription factor (TALE/PBX) family of proteins. The encoded protein is involved in several biological processes during embryogenesis including steroidogenesis, sexual development and the maintenance of hematopoietic stem cells. This prot...
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | limb development | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | regulation of neurogenesis | developmental process involved in reproduction | regulation of cell development | morphogenesis of an epithelium | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | embryonic appendage morphogenesis | cell differentiation | nervous system development | neurogenesis | generation of neurons | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | epithelial tube morphogenesis | limb morphogenesis | immune system development | renal tubule morphogenesis | branching involved in ureteric bud morphogenesis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | steroid biosynthetic process | regulation of G2/M transition of mitotic cell cycle | urogenital system development | nephron tubule morphogenesis | thymus development | embryonic limb morphogenesis | regulation of mitotic cell cycle phase transition | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | regulation of cell cycle phase transition | reproduction | embryonic skeletal system development | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | hemopoiesis | cellular biosynthetic process | kidney development | embryo development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | regulation of cell cycle G2/M phase transition | system development | nitrogen compound metabolic process | reproductive process | ureteric bud development | multicellular organism development | spleen development | lipid metabolic process | embryonic hemopoiesis | kidney morphogenesis | regulation of ossification | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of neuron differentiation | regulation of gene expression | kidney epithelium development | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | negative regulation of DNA-binding transcription factor activity | regulation of transcription by RNA polymerase II | positive regulation of cell cycle G2/M phase transition | biosynthetic process | aromatic compound biosynthetic process | mesonephric epithelium development | lipid biosynthetic process | endocrine system development | mesonephros development | proximal/distal pattern formation | chordate embryonic development | regulation of cellular metabolic process | renal tubule development | positive regulation of cell proliferation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | renal system development | embryonic morphogenesis | regulation of mitotic cell cycle | nephron development | ureteric bud morphogenesis | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regionalization | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | regulation of DNA-binding transcription factor activity | anatomical structure development | positive regulation of mitotic cell cycle phase transition | metabolic process | regulation of RNA biosynthetic process | embryonic organ development | adrenal gland development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | nephron morphogenesis | animal organ development | negative regulation of neuron differentiation | gene expression | transcription, DNA-templated | morphogenesis of a branching epithelium | steroid metabolic process | negative regulation of molecular function | regulation of transcription, DNA-templated | morphogenesis of a branching structure | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | developmental process | positive regulation of cell cycle process | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | skeletal system development | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | sex differentiation | negative regulation of cell development | nephron tubule development | negative regulation of cell differentiation | mesonephric tubule development | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular