QuickView for PDE8;jsessionid=5413A187A421498742EF633A24EB69C5;jsessionid=9D5EE44C1192827222D7CBE6282FE01F (gene)
- Gene Symbol:
- Pde8b
Rattus norvegicus - Full name:
- phosphodiesterase 8B
- Synonyms:
- RNPDE8B, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, cAMP-specific cyclic nucleotide phosphodiesterase PDE8
- Genomic Location:
- Chr 2: 25352725-25469209
- Description:
-
a cAMP-specific member of the PDE superfamily of cyclic nucleotide phosphodiesterases; involved in inhibition of intracellular cAMP signalling
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
| Transcripts Names |
|---|
| NM_199268 |
| XM_008760670 |
| XM_017590819 |
| XM_006231811 |
| XM_017590818 |
| XM_017590817 |
| XM_017590816 |
GO Molecular Function
cation binding | 3',5'-cyclic-AMP phosphodiesterase activity | hydrolase activity | cyclic-nucleotide phosphodiesterase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | metal ion binding | 3',5'-cyclic-nucleotide phosphodiesterase activity
GO Biological Process
response to radiation | behavioral fear response | regulation of cellular localization | negative regulation of peptide secretion | regulation of localization | negative regulation of cellular process | defense response | negative regulation of protein secretion | regulation of peptide hormone secretion | neuromuscular process controlling balance | cellular process | regulation of steroid hormone biosynthetic process | negative regulation of signaling | visual learning | learning | negative regulation of lipid biosynthetic process | negative regulation of secretion | negative regulation of hormone secretion | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | regulation of peptide secretion | associative learning | response to stimulus | negative regulation of protein transport | regulation of insulin secretion | response to stress | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of peptide transport | regulation of steroid biosynthetic process | regulation of steroid metabolic process | response to light stimulus | negative regulation of secretion by cell | learning or memory | regulation of insulin secretion involved in cellular response to glucose stimulus | regulation of hormone levels | regulation of hormone secretion | nervous system process | cognition | regulation of hormone metabolic process | negative regulation of peptide hormone secretion | cell communication | regulation of cellular metabolic process | regulation of lipid biosynthetic process | negative regulation of insulin secretion involved in cellular response to glucose stimulus | multicellular organismal response to stress | fear response | regulation of establishment of protein localization | visual behavior | negative regulation of lipid metabolic process | negative regulation of steroid hormone biosynthetic process | regulation of secretion | behavior | negative regulation of biosynthetic process | regulation of protein secretion | negative regulation of hormone biosynthetic process | regulation of cell communication | negative regulation of insulin secretion | signaling | neuromuscular process | operant conditioning | negative regulation of steroid metabolic process | behavioral defense response | regulation of transport | regulation of lipid metabolic process | regulation of protein localization | negative regulation of steroid biosynthetic process | signal transduction | regulation of signaling | regulation of hormone biosynthetic process | multicellular organismal process
GO Cellular Component
