QuickView for PDGFRA;jsessionid=834D13CAFD107F8D582533DDFB033B17;jsessionid=449B404E21880EC1C73D17906892CC1F (gene)

GO Molecular Function

transmembrane receptor protein tyrosine kinase activity | platelet-derived growth factor alpha-receptor activity | transmembrane signaling receptor activity | protein-containing complex binding | ribonucleotide binding | nucleotide binding | platelet-derived growth factor binding | carbohydrate derivative binding | growth factor binding | catalytic activity | ATP binding | platelet-derived growth factor-activated receptor activity | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

signal transduction involved in regulation of gene expression | regulation of ERK1 and ERK2 cascade | actin filament-based process | extracellular structure organization | cell motility | cranial skeletal system development | developmental process involved in reproduction | muscle tissue development | cellular response to platelet-derived growth factor stimulus | gonad development | regulation of programmed cell death | female gonad development | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | eye development | actin cytoskeleton organization | negative regulation of cellular process | cell differentiation | respiratory tube development | striated muscle cell development | glomerulus development | metanephric glomerulus development | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | estrogen metabolic process | cardiac cell development | blood vessel morphogenesis | cellular process | Leydig cell differentiation | localization | negative regulation of signaling | reproductive system development | immune system development | multicellular organismal reproductive process | negative regulation of apoptotic process | digestive tract morphogenesis | platelet-derived growth factor alpha-receptor activity | response to growth factor | positive regulation of nitrogen compound metabolic process | tissue development | metanephric nephron development | muscle structure development | muscle cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | head morphogenesis | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | urogenital system development | development of primary sexual characteristics | head development | response to stimulus | vasculature development | muscle cell development | respiratory system development | positive regulation of protein metabolic process | response to stress | ovulation cycle | roof of mouth development | tube morphogenesis | cardiac muscle tissue development | hematopoietic progenitor cell differentiation | development of primary female sexual characteristics | supramolecular fiber organization | reproduction | embryonic skeletal system development | cardiovascular system development | embryonic digestive tract morphogenesis | rhythmic process | extracellular matrix organization | metanephric glomerulus morphogenesis | hemopoiesis | cellular component assembly | protein modification process | kidney development | embryo development | macromolecule modification | cell chemotaxis | blood vessel development | locomotion | response to nitrogen compound | organelle assembly | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | cell migration | glomerulus vasculature development | regulation of MAPK cascade | phosphorus metabolic process | response to amino acid | platelet-derived growth factor-activated receptor activity | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | embryonic digestive tract development | wound healing | regulation of gene expression | platelet-derived growth factor receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | cardiocyte differentiation | luteinization | response to platelet-derived growth factor | cardiac myofibril assembly | regulation of cellular protein metabolic process | cardiac muscle cell development | angiogenesis | phosphorylation | actomyosin structure organization | digestive tract development | glomerulus morphogenesis | cellular response to amino acid stimulus | endocrine system development | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | ovulation cycle process | chordate embryonic development | striated muscle tissue development | cell communication | regulation of cellular metabolic process | skeletal system morphogenesis | metanephros development | regulation of protein metabolic process | positive regulation of signal transduction | glomerular capillary formation | heart development | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | renal system development | genitalia development | striated muscle cell differentiation | embryonic morphogenesis | nephron development | protein tyrosine kinase activity | multicellular organism reproduction | embryonic organ morphogenesis | embryonic cranial skeleton morphogenesis | development of primary male sexual characteristics | protein metabolic process | positive regulation of protein modification process | response to organic substance | gland development | digestive system development | retina development in camera-type eye | male sex differentiation | response to wounding | platelet-derived growth factor receptor-alpha signaling pathway | regulation of intracellular signal transduction | face morphogenesis | anatomical structure development | cell surface receptor signaling pathway | embryonic skeletal system morphogenesis | metabolic process | negative regulation of programmed cell death | embryonic organ development | male gonad development | adrenal gland development | metanephric glomerulus vasculature development | male genitalia development | protein kinase activity | organic substance metabolic process | animal organ development | positive regulation of ERK1 and ERK2 cascade | myofibril assembly | regulation of phosphate metabolic process | cytoskeleton organization | metanephric glomerular capillary formation | positive regulation of MAPK cascade | lung development | camera-type eye development | anatomical structure formation involved in morphogenesis | cardiac muscle cell differentiation | steroid metabolic process | regulation of cell communication | negative regulation of signal transduction | signaling | cell development | positive regulation of phosphorylation | cellular protein metabolic process | hormone metabolic process | anatomical structure morphogenesis | reproductive structure development | kinase activity | developmental process | organelle organization | cellular protein modification process | tube development | response to organonitrogen compound | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | retina vasculature development in camera-type eye | skeletal system development | immune system process | cellular metabolic process | body morphogenesis | hematopoietic or lymphoid organ development | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | negative regulation of cell death | circulatory system development | chemotaxis | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | face development | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | actin-based cell projection | cell | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | receptor complex | protein-containing complex | cell projection | plasma membrane | integral component of plasma membrane | microvillus | membrane-bounded organelle | nucleus | organelle | cell periphery | cell surface | intracellular | membrane | intrinsic component of plasma membrane

PATHWAYS

PID_ATF2_PATHWAY | PID_PDGFRA_PATHWAY | REACTOME_SIGNALING_BY_PDGF | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION

PROTEIN FAMILY

Protein kinase domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, receptor class III, conserved site | Immunoglobulin subtype 2 | Immunoglobulin subtype | Immunoglobulin-like domain | Tyrosine-protein kinase, active site | Protein kinase-like domain superfamily | Immunoglobulin I-set | Immunoglobulin-like fold | Protein kinase, ATP binding site | Tyrosine-protein kinase, catalytic domain | Platelet-derived growth factor receptor alpha | Immunoglobulin-like domain superfamily