QuickView for PDGFRB;jsessionid=9F68EF08CB8C49148706D2E282580348;jsessionid=7E133DED2D3BBC9D4337A88EE288762C (gene)
- Gene Symbol:
- PDGFRB
Canis lupus familiaris - Full name:
- platelet-derived growth factor receptor, beta polypeptide
- Synonyms:
- N/A
- Genomic Location:
- Chr 4: 62129887-62165819
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Bos taurus , Danio rerio , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
kinase binding | transmembrane receptor protein tyrosine kinase activity | vascular endothelial growth factor binding | protein kinase binding | transmembrane signaling receptor activity | platelet-derived growth factor receptor binding | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | platelet-derived growth factor binding | carbohydrate derivative binding | growth factor binding | catalytic activity | ATP binding | platelet-derived growth factor-activated receptor activity | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | growth factor receptor binding | drug binding | kinase activity | heterocyclic compound binding | platelet-derived growth factor beta-receptor activity | small molecule binding
GO Biological Process
positive regulation of smooth muscle cell proliferation | regulation of ERK1 and ERK2 cascade | positive regulation of locomotion | regulation of dephosphorylation | cell motility | intracellular signal transduction | cellular response to platelet-derived growth factor stimulus | regulation of localization | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | eye development | phosphatidylinositol metabolic process | positive regulation of phosphoprotein phosphatase activity | regulation of phosphatase activity | cell differentiation | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | positive regulation of cellular component movement | phospholipid metabolic process | blood vessel morphogenesis | positive regulation of dephosphorylation | positive regulation of phosphatidylinositol 3-kinase activity | cellular process | regulation of cell motility | localization | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | coronary vasculature morphogenesis | cellular lipid metabolic process | response to stimulus | vasculature development | cellular response to vascular endothelial growth factor stimulus | positive regulation of protein metabolic process | regulation of cell proliferation | tube morphogenesis | regulation of smooth muscle cell migration | positive regulation of phosphatase activity | phosphatidylinositol-mediated signaling | cardiovascular system development | positive regulation of lipase activity | platelet-derived growth factor receptor-beta signaling pathway | protein modification process | regulation of phosphatidylinositol 3-kinase activity | macromolecule modification | cell chemotaxis | positive regulation of protein dephosphorylation | blood vessel development | locomotion | positive regulation of phospholipase C activity | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | cell migration | regulation of MAPK cascade | phosphorus metabolic process | platelet-derived growth factor-activated receptor activity | positive regulation of smooth muscle cell migration | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | platelet-derived growth factor receptor signaling pathway | organophosphate metabolic process | coronary vasculature development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | vascular endothelial growth factor signaling pathway | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway | regulation of cellular component movement | positive regulation of hydrolase activity | response to platelet-derived growth factor | positive regulation of cell migration | cell migration involved in vasculogenesis | regulation of cellular protein metabolic process | angiogenesis | phosphorylation | angiogenesis involved in coronary vascular morphogenesis | regulation of phospholipase activity | inositol lipid-mediated signaling | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | regulation of lipid kinase activity | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | heart development | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | glycerolipid metabolic process | regulation of phospholipid metabolic process | protein tyrosine kinase activity | regulation of phospholipase C activity | cell migration involved in heart development | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | response to organic substance | retina development in camera-type eye | regulation of protein dephosphorylation | regulation of kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | protein kinase activity | organic substance metabolic process | animal organ development | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of phospholipase activity | positive regulation of MAPK cascade | camera-type eye development | anatomical structure formation involved in morphogenesis | regulation of cell communication | signaling | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | glycerophospholipid metabolic process | regulation of phosphoprotein phosphatase activity | kinase activity | developmental process | cell migration involved in coronary angiogenesis | cellular protein modification process | tube development | positive regulation of lipid kinase activity | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | retina vasculature development in camera-type eye | cellular metabolic process | cellular response to organic substance | regulation of smooth muscle cell proliferation | positive regulation of cell motility | circulatory system development | chemotaxis | platelet-derived growth factor beta-receptor activity | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | apical plasma membrane | cytoplasmic vesicle | cell | vacuolar lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | apical part of cell | Golgi apparatus | endomembrane system | plasma membrane | vacuole | vesicle | lytic vacuole | membrane-bounded organelle | nucleus | organelle | lysosome | cell periphery | membrane-enclosed lumen | lysosomal lumen | intracellular vesicle | intracellular | membrane | intrinsic component of plasma membrane
