QuickView for PGR;jsessionid=0C63B765A62B10E7D00A3924F7A4AD8C;jsessionid=79B9F98D9F393E93294B072931DA8DAE (gene)
- Gene Symbol:
- Pgr
Mus musculus - Full name:
- progesterone receptor
- Synonyms:
- 9930019P03Rik, BB114106, NR3C3, PR, PR-A, PR-B, progesterone receptor, nuclear receptor subfamily 3 group C member 3
- Genomic Location:
- Chr 9: 8899833-8968611
- Description:
-
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | lipid binding | signaling receptor binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | steroid hormone receptor activity | ATPase binding | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | identical protein binding | ion binding | organic cyclic compound binding | hormone binding | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transition metal ion binding | steroid binding | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | developmental process involved in reproduction | regulation of localization | mammary gland duct morphogenesis | morphogenesis of an epithelium | gonad development | regulation of programmed cell death | female gonad development | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | respiratory tube development | response to drug | positive regulation of cellular component movement | tertiary branching involved in mammary gland duct morphogenesis | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | nuclear receptor activity | regulation of cell motility | epithelial tube morphogenesis | cell maturation | reproductive system development | female pregnancy | transcription factor activity, direct ligand regulated sequence-specific DNA binding | multicellular organismal reproductive process | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | tissue development | gamete generation | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | mammary gland morphogenesis | development of primary sexual characteristics | response to stimulus | negative regulation of epithelial cell apoptotic process | ovulation | female gamete generation | respiratory system development | female mating behavior | response to cocaine | gland morphogenesis | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | ovulation cycle | tube morphogenesis | epithelial cell development | regulation of smooth muscle cell migration | development of primary female sexual characteristics | reproduction | rhythmic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | regulation of granulosa cell apoptotic process | cellular biosynthetic process | ovulation from ovarian follicle | cell-cell signaling | regulation of nucleic acid-templated transcription | response to nitrogen compound | lung alveolus development | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | mammary gland development | positive regulation of smooth muscle cell migration | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | progesterone receptor signaling pathway | animal organ morphogenesis | response to ammonium ion | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | regulation of transcription by RNA polymerase II | paracrine signaling | positive regulation of cell migration | negative regulation of granulosa cell apoptotic process | biosynthetic process | aromatic compound biosynthetic process | response to xenobiotic stimulus | regulation of epithelial cell apoptotic process | ovulation cycle process | epithelial cell maturation | cell communication | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of locomotion | regulation of RNA metabolic process | multicellular organism reproduction | maternal process involved in female pregnancy | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to organic substance | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | anatomical structure development | reproductive behavior | metabolic process | regulation of RNA biosynthetic process | developmental maturation | negative regulation of programmed cell death | mating behavior | behavior | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | mating | animal organ development | gene expression | mammary gland branching involved in pregnancy | mammary gland epithelium development | response to alkaloid | cellular response to steroid hormone stimulus | transcription, DNA-templated | lung development | intracellular receptor signaling pathway | morphogenesis of a branching epithelium | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | morphogenesis of a branching structure | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | intracellular steroid hormone receptor signaling pathway | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | response to anesthetic | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cell motility | response to steroid hormone | negative regulation of cell death | branching involved in mammary gland duct morphogenesis | sexual reproduction | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
dendritic spine | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | distal axon | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | presynapse | cell projection | endomembrane system | neuron spine | postsynapse | plasma membrane | perikaryon | mitochondrion | membrane-bounded organelle | nucleus | organelle | axon terminus | cell periphery | axon | neuron projection terminus | cytosol | intracellular | membrane
