QuickView for PI3K;jsessionid=E940161A07BEDF9DE3846F7595030CAD;jsessionid=B3C63F7BABBB24552774D032121F3D3E (gene)
- Gene Symbol:
- Pik3cb
Rattus norvegicus - Full name:
- phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- Synonyms:
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, PI3-kinase p110 subunit beta, PI3-kinase subunit beta, PI3K, PI3K-beta, PI3Kbeta, catalytic phosphatidylinositol 3-kinase beta, p110beta, phosphatidylinositol 3-kinase, catalytic subunit, beta isoform, phosphatidylinositol 3-kinase, catalytic, beta polypeptide, phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, phosphoinositide-3-kinase, catalytic, beta polypeptide, ptdIns-3-kinase p110, ptdIns-3-kinase subunit beta, ptdIns-3-kinase subunit p110-beta
- Genomic Location:
- Chr 8: 103886682-103957112
- Description:
-
may play a role in hepatocyte proliferation and DNA replication
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
| Transcripts Names |
|---|
| NM_053481 |
| XM_017595947 |
| XM_017595946 |
| XM_008766567 |
| XM_017595944 |
| XM_017595943 |
| XM_006243642 |
GO Molecular Function
phosphatidylinositol phosphate kinase activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | 1-phosphatidylinositol-4-phosphate 3-kinase activity | purine nucleotide binding | phosphatidylinositol 3-kinase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | 1-phosphatidylinositol-3-kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | insulin receptor substrate binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of myeloid cell apoptotic process | cell motility | intracellular signal transduction | phosphatidylinositol phosphate kinase activity | positive regulation of apoptotic process | positive regulation of neutrophil apoptotic process | regulation of programmed cell death | phosphatidylinositol metabolic process | establishment of localization | regulation of immune system process | cellular chemical homeostasis | phosphatidylinositol-3-phosphate biosynthetic process | phospholipid metabolic process | blood vessel morphogenesis | cellular process | localization | cellular homeostasis | hemostasis | endothelial cell proliferation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | cellular lipid metabolic process | calcium ion homeostasis | response to stimulus | vasculature development | positive regulation of immune system process | response to stress | tube morphogenesis | phosphatidylinositol-mediated signaling | cardiovascular system development | protein modification process | regulation of cell adhesion | cellular biosynthetic process | embryo development | macromolecule modification | metal ion homeostasis | blood vessel development | blood coagulation | locomotion | system development | nitrogen compound metabolic process | multicellular organism development | cell migration | phosphorus metabolic process | lipid metabolic process | wound healing | regulation of gene expression | platelet activation | organophosphate metabolic process | cellular ion homeostasis | 1-phosphatidylinositol-4-phosphate 3-kinase activity | phospholipid biosynthetic process | regulation of cell-substrate adhesion | vesicle-mediated transport | phosphatidylinositol 3-kinase activity | cell proliferation | biosynthetic process | cell division | angiogenesis | phosphorylation | lipid biosynthetic process | inositol lipid-mediated signaling | positive regulation of leukocyte apoptotic process | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | autophagy | lipid phosphorylation | cellular cation homeostasis | cell communication | cellular calcium ion homeostasis | lipid modification | homeostatic process | glycerolipid metabolic process | coagulation | protein metabolic process | glycerophospholipid biosynthetic process | 1-phosphatidylinositol-3-kinase activity | epithelial cell proliferation | response to wounding | import into cell | phosphatidylinositol 3-kinase signaling | anatomical structure development | metabolic process | regulation of body fluid levels | chemical homeostasis | endocytosis | positive regulation of cell death | cell adhesion | regulation of myeloid cell apoptotic process | organic substance metabolic process | positive regulation of programmed cell death | ion homeostasis | phosphatidylinositol biosynthetic process | cell-cell adhesion | embryonic cleavage | angiogenesis involved in wound healing | cell activation | anatomical structure formation involved in morphogenesis | signaling | cellular protein metabolic process | phosphatidylinositol phosphorylation | anatomical structure morphogenesis | glycerophospholipid metabolic process | kinase activity | developmental process | cellular protein modification process | tube development | cellular metal ion homeostasis | cell-cell adhesion via plasma-membrane adhesion molecules | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | circulatory system development | divalent inorganic cation homeostasis | signal transduction | positive regulation of gene expression | regulation of cell-matrix adhesion | homophilic cell adhesion via plasma membrane adhesion molecules | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
brush border | intracellular membrane-bounded organelle | catalytic complex | phosphatidylinositol 3-kinase complex | extrinsic component of membrane | cell projection membrane | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | brush border membrane | protein-containing complex | cell projection | plasma membrane | midbody | transferase complex | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
