Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for PIK3CA;jsessionid=C1F3D265E9968C34258BDE3DB3DA01C9;jsessionid=C2854C56D9A5D3869D37057FCE1341EA (gene)


Gene Symbol:
Pik3ca Mus musculus Mus musculus
Full name:
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Synonyms:
6330412C24Rik, caPI3K, p110, p110alpha, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, phosphatidylinositol 3-kinase, catalytic, alpha polypeptide, phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, phosphoinositide-3-kinase catalytic alpha polypeptide, ptdIns-3-kinase subunit alpha, ptdIns-3-kinase subunit p110-alpha, serine/threonine protein kinase PIK3CA
Genomic Location:
Chr 3: 32335128-32361753
Orthologs:
Homo sapiens Rattus norvegicus C. elegans Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_008839
XM_006535410
XM_006535409
Protein Names
Q0VGQ5
P42337



GO Molecular Function

protein kinase activator activity | phosphatidylinositol phosphate kinase activity | enzyme activator activity | protein kinase regulator activity | kinase regulator activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | 1-phosphatidylinositol-4-phosphate 3-kinase activity | purine nucleotide binding | phosphatidylinositol 3-kinase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | protein binding | 1-phosphatidylinositol-3-kinase activity | kinase activator activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | insulin receptor substrate binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of smooth muscle cell proliferation | adipose tissue development | protein kinase activator activity | cellular response to glucose stimulus | cell motility | intracellular signal transduction | phosphatidylinositol phosphate kinase activity | enzyme activator activity | protein kinase regulator activity | regulation of programmed cell death | phosphatidylinositol metabolic process | establishment of localization | regulation of DNA methylation | negative regulation of neuron death | negative regulation of cellular process | glucose metabolic process | cellular chemical homeostasis | glucose homeostasis | positive regulation of phosphate metabolic process | phosphatidylinositol-3-phosphate biosynthetic process | phospholipid metabolic process | blood vessel morphogenesis | regulation of neuron death | cellular process | localization | cellular homeostasis | positive regulation of peptidyl-serine phosphorylation | kinase regulator activity | negative regulation of anoikis | positive regulation of protein kinase activity | hemostasis | negative regulation of apoptotic process | positive regulation of catalytic activity | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | hepaticobiliary system development | positive regulation of cellular protein metabolic process | cellular lipid metabolic process | response to stimulus | vasculature development | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | multicellular organismal homeostasis | tube morphogenesis | response to glucose | protein serine/threonine kinase activity | phosphatidylinositol-mediated signaling | cardiovascular system development | negative regulation of metabolic process | regulation of anoikis | protein modification process | cellular biosynthetic process | macromolecule modification | activation of protein kinase activity | molecular function regulator | blood vessel development | blood coagulation | locomotion | negative regulation of neuron apoptotic process | protein kinase B signaling | system development | nitrogen compound metabolic process | multicellular organism development | cell migration | cellular glucose homeostasis | phosphorus metabolic process | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | wound healing | regulation of gene expression | platelet activation | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | 1-phosphatidylinositol-4-phosphate 3-kinase activity | liver development | phospholipid biosynthetic process | regulation of nitrogen compound metabolic process | regulation of genetic imprinting | monosaccharide metabolic process | small molecule metabolic process | vesicle-mediated transport | phosphatidylinositol 3-kinase activity | biosynthetic process | regulation of cellular protein metabolic process | angiogenesis | phosphorylation | lipid biosynthetic process | carbohydrate metabolic process | inositol lipid-mediated signaling | protein phosphorylation | phosphate-containing compound metabolic process | lipid phosphorylation | energy homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | regulation of protein metabolic process | lipid modification | homeostatic process | positive regulation of cell proliferation | response to monosaccharide | regulation of protein phosphorylation | glycerolipid metabolic process | coagulation | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | glycerophospholipid biosynthetic process | 1-phosphatidylinositol-3-kinase activity | regulation of cellular respiration | regulation of kinase activity | response to wounding | import into cell | phosphatidylinositol 3-kinase signaling | anatomical structure development | kinase activator activity | metabolic process | hexose metabolic process | regulation of body fluid levels | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | chemical homeostasis | endocytosis | protein kinase activity | organic substance metabolic process | connective tissue development | negative regulation of gene expression | animal organ development | positive regulation of kinase activity | hypomethylation of CpG island | regulation of phosphate metabolic process | phosphatidylinositol biosynthetic process | cell activation | regulation of peptidyl-serine phosphorylation | anatomical structure formation involved in morphogenesis | signaling | regulation of developmental growth | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | phosphatidylinositol phosphorylation | anatomical structure morphogenesis | regulation of developmental process | glycerophospholipid metabolic process | kinase activity | developmental process | cellular protein modification process | negative regulation of fibroblast apoptotic process | tube development | regulation of fibroblast apoptotic process | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | response to carbohydrate | negative regulation of cell death | circulatory system development | carbohydrate homeostasis | phagocytosis | signal transduction | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

catalytic complex | phosphatidylinositol 3-kinase complex | extrinsic component of membrane | cell | lamellipodium | cytoplasm | protein-containing complex | cell projection | plasma membrane | cell leading edge | transferase complex | phosphatidylinositol 3-kinase complex, class IA | cell periphery | intracellular | membrane