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QuickView for PINK1;jsessionid=43F0DD9FAA73303C2B7D4A41AD96D8C5;jsessionid=247DC592416F6B69595ABE97A9F20C5D (gene)


Gene Symbol:
PINK1 Gallus gallus Gallus gallus
Full name:
PTEN induced putative kinase 1
Synonyms:
N/A
Genomic Location:
Chr 21: 4955890-4965341
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
XM_423139
Protein Names
No proteins found.



GO Molecular Function

kinase binding | calcium-dependent protein kinase activity | cation binding | protein kinase binding | magnesium ion binding | protein kinase B binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | protein domain specific binding | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | C3HC4-type RING finger domain binding | purine ribonucleoside triphosphate binding | protein binding | ubiquitin protein ligase binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | protease binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of deacetylase activity | regulation of hydrogen peroxide-induced cell death | cellular response to decreased oxygen levels | positive regulation of macromolecule biosynthetic process | regulation of dephosphorylation | regulation of intracellular protein transport | regulation of cellular response to oxidative stress | positive regulation of cellular component organization | regulation of response to oxidative stress | regulation of cellular localization | positive regulation of ATP metabolic process | intracellular signal transduction | positive regulation of apoptotic process | regulation of vacuole organization | protein stabilization | protein localization to mitochondrion | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | negative regulation of cellular response to oxidative stress | peptidyl-amino acid modification | regulation of mitochondrial fission | establishment of localization | regulation of autophagy | negative regulation of neuron death | negative regulation of cellular process | positive regulation of histone deacetylase activity | positive regulation of developmental process | negative regulation of mitochondrion organization | generation of precursor metabolites and energy | positive regulation of phosphate metabolic process | regulation of organelle organization | calcium-dependent protein kinase activity | autophagy of mitochondrion | regulation of neuron death | positive regulation of dephosphorylation | positive regulation of oxidative phosphorylation | positive regulation of cellular biosynthetic process | cellular process | regulation of catecholamine secretion | negative regulation of oxidative stress-induced neuron death | localization | positive regulation of synaptic transmission | regulation of mitochondrial membrane potential | negative regulation of macroautophagy | negative regulation of signaling | positive regulation of peptidyl-serine phosphorylation | cellular respiration | establishment of protein localization to mitochondrion | macromolecule localization | regulation of histone modification | negative regulation of apoptotic process | response to hypoxia | positive regulation of release of cytochrome c from mitochondria | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of autophagosome assembly | regulation of oxidative phosphorylation | negative regulation of apoptotic signaling pathway | negative regulation of hydrogen peroxide-mediated programmed cell death | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | positive regulation of translation | positive regulation of cellular protein metabolic process | negative regulation of oxidative stress-induced cell death | negative regulation of response to drug | maintenance of protein location in mitochondrion | cellular component organization | positive regulation of autophagy of mitochondrion | positive regulation of synaptic transmission, dopaminergic | response to stimulus | lysosomal transport | regulation of mitochondrial ATP synthesis coupled electron transport | regulation of cellular protein localization | positive regulation of protein metabolic process | negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway | cellular response to hypoxia | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | response to stress | vacuolar transport | regulation of response to drug | posttranscriptional regulation of gene expression | regulation of protein ubiquitination | electron transport chain | positive regulation of protein deacetylation | protein serine/threonine kinase activity | cellular localization | regulation of histone deacetylase activity | cellular response to toxic substance | maintenance of protein localization in organelle | positive regulation of mitophagy in response to mitochondrial depolarization | regulation of macroautophagy | regulation of protein transport | negative regulation of metabolic process | protein modification process | negative regulation of autophagosome assembly | mitochondrion to lysosome transport | regulation of peptide transport | modulation of chemical synaptic transmission | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | mitochondrion organization | macromolecule modification | positive regulation of protein dephosphorylation | negative regulation of autophagy of mitochondrion | regulation of intracellular transport | positive regulation of mitochondrion organization | regulation of nucleic acid-templated transcription | regulation of membrane potential | regulation of cellular response to stress | negative regulation of neuron apoptotic process | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | regulation of cellular response to hypoxia | regulation of protein stability | phosphorus metabolic process | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | positive regulation of catecholamine secretion | positive regulation of mitochondrial electron transport, NADH to ubiquinone | regulation of catalytic activity | cellular response to oxidative stress | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | positive regulation of chromosome organization | regulation of gene expression | positive regulation of secretion | cellular response to stress | negative regulation of hydrogen peroxide-induced cell death | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | mitochondrial transport | cellular response to oxygen levels | protein autophosphorylation | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | positive regulation of intracellular signal transduction | vesicle-mediated transport | response to oxidative stress | regulation of synaptic transmission, dopaminergic | protein localization to organelle | positive regulation of hydrolase activity | positive regulation of cellular respiration | regulation of cellular protein metabolic process | phosphorylation | response to toxic substance | regulation of hydrogen peroxide metabolic process | regulation of apoptotic signaling pathway | protein phosphorylation | negative regulation of hydrogen peroxide-induced neuron death | phosphate-containing compound metabolic process | autophagy | negative regulation of autophagy | regulation of mitochondrion organization | regulation of cellular response to drug | maintenance of protein location | positive regulation of histone deacetylation | cell communication | regulation of cellular metabolic process | regulation of protein deacetylation | positive regulation of response to drug | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of signal transduction | negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | regulation of dopamine secretion | regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | organelle disassembly | regulation of autophagy of mitochondrion | positive regulation of molecular function | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | protein ubiquitination | regulation of cellular respiration | regulation of protein dephosphorylation | regulation of response to reactive oxygen species | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | establishment of protein localization to organelle | peptidyl-serine autophosphorylation | metabolic process | negative regulation of response to oxidative stress | regulation of protein targeting | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of programmed cell death | negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway | cellular protein localization | regulation of secretion | positive regulation of cell death | protein kinase activity | organic substance metabolic process | negative regulation of intrinsic apoptotic signaling pathway | negative regulation of gene expression | positive regulation of ion transport | positive regulation of histone modification | positive regulation of programmed cell death | protein modification by small protein conjugation or removal | maintenance of protein location in cell | regulation of ATP metabolic process | regulation of phosphate metabolic process | regulation of chromosome organization | positive regulation of autophagy | establishment of protein localization | positive regulation of macroautophagy | regulation of mitochondrial electron transport, NADH to ubiquinone | regulation of peptidyl-serine phosphorylation | regulation of cell communication | response to mitochondrial depolarisation | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | positive regulation of mitochondrial fission | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | positive regulation of dopamine secretion | cellular macromolecule localization | regulation of developmental process | regulation of ion transport | energy derivation by oxidation of organic compounds | kinase activity | organelle organization | positive regulation of mitophagy | peptidyl-serine phosphorylation | cellular protein modification process | positive regulation of cristae formation | regulation of transport | regulation of reactive oxygen species metabolic process | negative regulation of mitochondrial fission | regulation of histone deacetylation | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | cellular metabolic process | regulation of protein localization | regulation of cell death | regulation of organelle assembly | regulation of translation | negative regulation of cell death | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | negative regulation of cellular response to hypoxia | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | positive regulation of mitochondrial ATP synthesis coupled electron transport | maintenance of location in cell | respiratory electron transport chain | regulation of protein targeting to mitochondrion | regulation of chromatin organization | regulation of phosphorus metabolic process

GO Cellular Component

integral component of organelle membrane | integral component of membrane | mitochondrial intermembrane space | organelle inner membrane | chromosome | intracellular membrane-bounded organelle | mitochondrial inner membrane | neuron projection | organelle membrane | cell body | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | outer mitochondrial membrane protein complex | intracellular organelle | glial cell projection | protein-containing complex | cell projection | chromatin | perinuclear region of cytoplasm | TORC2 complex | mitochondrion | mitochondrial outer membrane translocase complex | intrinsic component of mitochondrial outer membrane | membrane-bounded organelle | astrocyte projection | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | axon | membrane-enclosed lumen | outer membrane | integral component of mitochondrial membrane | mitochondrial membrane | cytosol | cytoskeleton | intracellular | integral component of mitochondrial outer membrane | membrane