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QuickView for PRDX5;jsessionid=4BFA3D4BED289AB1CD2C9140D9920BAD;jsessionid=ADED11D8CD7190D7E15C828EEB5EC8AB (gene)


Gene Symbol:
Prdx5 Mus musculus Mus musculus
Full name:
peroxiredoxin 5
Synonyms:
AOEB166, AOPP, PLP, Pmp20, Prdx6, PrxV, peroxiredoxin-5, mitochondrial, antioxidant enzyme B166, liver tissue 2D-page spot 2D-0014IV, peroxiredoxin 6, peroxiredoxin V, peroxisomal antioxidant enzyme, peroxisomal membrane protein 20, thioredoxin peroxidase PMP20, thioredoxin reductase
Genomic Location:
Chr 19: 6981309-6984135
Description:
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites may result in use of alternate...
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012021
NM_001358444
Protein Names
Q9QX45
P99029
Q9QZ75



GO Molecular Function

endopeptidase inhibitor activity | peroxynitrite reductase activity | transcription regulatory region DNA binding | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | thioredoxin peroxidase activity | peroxidase activity | antioxidant activity | nucleic acid binding | enzyme inhibitor activity | signaling receptor binding | molecular function regulator | catalytic activity | DNA binding | peroxiredoxin activity | organic cyclic compound binding | protein binding | protein dimerization activity | cysteine-type endopeptidase regulator activity involved in apoptotic process | peptidase inhibitor activity | enzyme regulator activity | RNA polymerase III regulatory region DNA binding | oxidoreductase activity, acting on peroxide as acceptor | heterocyclic compound binding | oxidoreductase activity | cysteine-type endopeptidase inhibitor activity

GO Biological Process

regulation of cysteine-type endopeptidase activity | endopeptidase inhibitor activity | peroxynitrite reductase activity | homeostasis of number of cells within a tissue | positive regulation of collagen metabolic process | regulation of programmed cell death | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | negative regulation of cysteine-type endopeptidase activity | thioredoxin peroxidase activity | negative regulation of cellular process | peroxidase activity | negative regulation of RNA biosynthetic process | hydrogen peroxide catabolic process | reactive oxygen species metabolic process | tissue homeostasis | negative regulation of proteolysis | cellular process | cellular homeostasis | cellular detoxification | antioxidant activity | nucleotide metabolic process | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of transcription by RNA polymerase III | anatomical structure homeostasis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | enzyme inhibitor activity | response to stress | cell redox homeostasis | multicellular organismal homeostasis | programmed cell death | cellular nitrogen compound metabolic process | cellular response to toxic substance | negative regulation of metabolic process | cofactor metabolic process | drug catabolic process | molecular function regulator | regulation of nucleic acid-templated transcription | apoptotic process | nitrogen compound metabolic process | negative regulation of catalytic activity | antibiotic metabolic process | regulation of peptidase activity | phosphorus metabolic process | regulation of collagen biosynthetic process | regulation of catalytic activity | cellular response to oxidative stress | negative regulation of peptidase activity | regulation of gene expression | cellular response to stress | organophosphate metabolic process | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | small molecule metabolic process | response to oxidative stress | NADPH oxidation | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | nucleobase-containing small molecule metabolic process | homeostasis of number of cells | regulation of cellular protein metabolic process | peroxiredoxin activity | response to toxic substance | regulation of apoptosis involved in tissue homeostasis | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of collagen metabolic process | regulation of protein metabolic process | homeostatic process | negative regulation of transcription by RNA polymerase III | regulation of RNA metabolic process | drug metabolic process | reactive nitrogen species metabolic process | metabolic process | cellular oxidant detoxification | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | response to reactive oxygen species | negative regulation of cellular protein metabolic process | negative regulation of protein metabolic process | cysteine-type endopeptidase regulator activity involved in apoptotic process | negative regulation of molecular function | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | NADP metabolic process | nicotinamide nucleotide metabolic process | detoxification | negative regulation of oxidoreductase activity | heterocycle metabolic process | negative regulation of hydrolase activity | oxidoreductase activity, acting on peroxide as acceptor | hydrogen peroxide metabolic process | positive regulation of metabolic process | positive regulation of collagen biosynthetic process | cellular metabolic process | regulation of cell death | oxidoreductase activity | cysteine-type endopeptidase inhibitor activity | negative regulation of cell death | negative regulation of endopeptidase activity | multicellular organismal process

GO Cellular Component

peroxisomal matrix | intracellular membrane-bounded organelle | peroxisome | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | vesicle | perinuclear region of cytoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular vesicle | intracellular