QuickView for PRDX5;jsessionid=4BFA3D4BED289AB1CD2C9140D9920BAD;jsessionid=A18162AE2BD8C69B2594FA4164902E0D (gene)
- Gene Symbol:
- Prdx5
Rattus norvegicus - Full name:
- peroxiredoxin 5
- Synonyms:
- Aoeb166, peroxiredoxin-5, mitochondrial, PLP, antioxidant enzyme B166, peroxiredoxin V, peroxisomal antioxidant enzyme, prx-V, thioredoxin peroxidase PMP20, thioredoxin reductase
- Genomic Location:
- Chr 1: 209583414-209586399
- Description:
-
member of the AhpC/TSA peroxiredoxin family with mitochondrial and peroxisomal sorting signals; may play an antioxidant protective role in various tissues
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
endopeptidase inhibitor activity | peroxynitrite reductase activity | transcription regulatory region DNA binding | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | thioredoxin peroxidase activity | peroxidase activity | antioxidant activity | nucleic acid binding | enzyme inhibitor activity | signaling receptor binding | molecular function regulator | catalytic activity | DNA binding | peroxiredoxin activity | organic cyclic compound binding | protein binding | protein dimerization activity | cysteine-type endopeptidase regulator activity involved in apoptotic process | peptidase inhibitor activity | enzyme regulator activity | RNA polymerase III regulatory region DNA binding | oxidoreductase activity, acting on peroxide as acceptor | heterocyclic compound binding | oxidoreductase activity | cysteine-type endopeptidase inhibitor activity
GO Biological Process
regulation of cysteine-type endopeptidase activity | endopeptidase inhibitor activity | peroxynitrite reductase activity | homeostasis of number of cells within a tissue | positive regulation of collagen metabolic process | regulation of programmed cell death | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | negative regulation of cysteine-type endopeptidase activity | thioredoxin peroxidase activity | negative regulation of cellular process | peroxidase activity | negative regulation of RNA biosynthetic process | hydrogen peroxide catabolic process | reactive oxygen species metabolic process | tissue homeostasis | negative regulation of proteolysis | cellular process | cellular homeostasis | cellular detoxification | antioxidant activity | nucleotide metabolic process | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of transcription by RNA polymerase III | anatomical structure homeostasis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | enzyme inhibitor activity | response to stress | cell redox homeostasis | multicellular organismal homeostasis | programmed cell death | cellular nitrogen compound metabolic process | cellular response to toxic substance | negative regulation of metabolic process | cofactor metabolic process | drug catabolic process | molecular function regulator | regulation of nucleic acid-templated transcription | apoptotic process | nitrogen compound metabolic process | negative regulation of catalytic activity | antibiotic metabolic process | regulation of peptidase activity | phosphorus metabolic process | regulation of collagen biosynthetic process | regulation of catalytic activity | cellular response to oxidative stress | negative regulation of peptidase activity | regulation of gene expression | cellular response to stress | organophosphate metabolic process | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | small molecule metabolic process | response to oxidative stress | NADPH oxidation | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | nucleobase-containing small molecule metabolic process | homeostasis of number of cells | regulation of cellular protein metabolic process | peroxiredoxin activity | response to toxic substance | regulation of apoptosis involved in tissue homeostasis | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of collagen metabolic process | regulation of protein metabolic process | homeostatic process | negative regulation of transcription by RNA polymerase III | regulation of RNA metabolic process | drug metabolic process | reactive nitrogen species metabolic process | metabolic process | cellular oxidant detoxification | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | response to reactive oxygen species | negative regulation of cellular protein metabolic process | negative regulation of protein metabolic process | cysteine-type endopeptidase regulator activity involved in apoptotic process | negative regulation of molecular function | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | NADP metabolic process | nicotinamide nucleotide metabolic process | detoxification | negative regulation of oxidoreductase activity | heterocycle metabolic process | negative regulation of hydrolase activity | oxidoreductase activity, acting on peroxide as acceptor | hydrogen peroxide metabolic process | positive regulation of metabolic process | positive regulation of collagen biosynthetic process | cellular metabolic process | regulation of cell death | oxidoreductase activity | cysteine-type endopeptidase inhibitor activity | negative regulation of cell death | negative regulation of endopeptidase activity | multicellular organismal process
GO Cellular Component
peroxisomal matrix | intracellular membrane-bounded organelle | peroxisome | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | vesicle | perinuclear region of cytoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular vesicle | intracellular
