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QuickView for PRKDC;jsessionid=ED766658D5CC832C9FA2EDF8AA35B258;jsessionid=8F3B895C73385C861687937EB40F1E2C (gene)


Gene Symbol:
PRKDC Canis lupus familiaris Canis lupus familiaris
Full name:
protein kinase, DNA-activated, catalytic polypeptide
Synonyms:
N/A
Genomic Location:
Chr 29: 3026453-3245935
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001006651
Protein Names
Q8WN22



GO Molecular Function

enzyme binding | nucleic acid binding | ribonucleotide binding | DNA-dependent protein kinase activity | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | DNA binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | double-stranded DNA binding | transcription factor binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of immune response | negative regulation of phosphorylation | brain development | double-strand break repair | response to radiation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | telomere maintenance | developmental process involved in reproduction | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell cycle G1/S phase transition | regulation of programmed cell death | T cell lineage commitment | peptidyl-amino acid modification | regulation of immune system process | response to hormone | negative regulation of cellular process | telomere capping | cell differentiation | defense response | nervous system development | intrinsic apoptotic signaling pathway in response to DNA damage | negative regulation of protein phosphorylation | regulation of G1/S transition of mitotic cell cycle | B cell differentiation | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | lymphocyte differentiation | mitotic DNA integrity checkpoint | lymphoid progenitor cell differentiation | negative regulation of G1/S transition of mitotic cell cycle | immune system development | negative regulation of apoptotic process | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | anatomical structure homeostasis | intrinsic apoptotic signaling pathway | T cell receptor V(D)J recombination | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | signal transduction involved in mitotic DNA damage checkpoint | cellular component organization | DNA-dependent protein kinase activity | T cell activation | head development | response to stimulus | pro-B cell differentiation | positive regulation of innate immune response | regulation of mitotic cell cycle phase transition | positive regulation of immune system process | response to stress | regulation of cell proliferation | response to peptide | regulation of cell cycle phase transition | hematopoietic progenitor cell differentiation | protein serine/threonine kinase activity | programmed cell death | protein destabilization | activation of innate immune response | reproduction | rhythmic process | cellular nitrogen compound metabolic process | telomere organization | double-strand break repair via nonhomologous end joining | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | embryo development | DNA recombination | macromolecule modification | DNA repair | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | leukocyte differentiation | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | regulation of protein stability | negative regulation of phosphate metabolic process | mitotic DNA damage checkpoint | multicellular organism development | cellular response to peptide hormone stimulus | phosphorus metabolic process | cellular response to DNA damage stimulus | cellular response to insulin stimulus | regulation of phosphorylation | somatic recombination of immunoglobulin gene segments | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | cellular response to peptide | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | B cell activation | V(D)J recombination | cell proliferation | regulation of cellular protein metabolic process | phosphorylation | signal transduction involved in cell cycle checkpoint | programmed cell death involved in cell development | protein phosphorylation | response to gamma radiation | phosphate-containing compound metabolic process | mitotic G1 DNA damage checkpoint | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | heart development | homeostatic process | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | apoptotic signaling pathway | regulation of mitotic cell cycle | lymphocyte activation | T cell differentiation | activation of immune response | protein metabolic process | regionalization | response to organic substance | regulation of innate immune response | T cell differentiation in thymus | G1 DNA damage checkpoint | DNA metabolic process | response to insulin | anatomical structure development | mitotic cell cycle | metabolic process | cell fate commitment | immunoglobulin production | regulation of RNA biosynthetic process | negative regulation of programmed cell death | somatic diversification of immunoglobulins | negative regulation of mitotic cell cycle | positive regulation of cell death | immune response | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | cell death | animal organ development | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | signal transduction involved in mitotic cell cycle checkpoint | regulation of phosphate metabolic process | cell activation | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | negative regulation of protein metabolic process | B cell lineage commitment | negative regulation of cell cycle G1/S phase transition | signaling | somite development | regulation of transcription, DNA-templated | cell development | cellular protein metabolic process | anatomical structure morphogenesis | somatic cell DNA recombination | signal transduction involved in DNA damage checkpoint | regulation of circadian rhythm | kinase activity | segmentation | developmental process | organelle organization | peptidyl-serine phosphorylation | cellular protein modification process | mitotic G1/S transition checkpoint | positive regulation of transcription, DNA-templated | innate immune response | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | somitogenesis | signal transduction involved in mitotic G1 DNA damage checkpoint | central nervous system development | positive regulation of metabolic process | chromosome organization | immune system process | mitotic cell cycle checkpoint | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | cellular response to organic substance | regulation of cell death | ectopic germ cell programmed cell death | regulation of smooth muscle cell proliferation | DNA damage checkpoint | cell cycle checkpoint | negative regulation of cell death | circulatory system development | response to ionizing radiation | immunoglobulin V(D)J recombination | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | DNA repair complex | cell | nuclear lumen | transcription factor complex | nucleolus | intracellular organelle | protein-containing complex | nonhomologous end joining complex | protein-DNA complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | DNA-dependent protein kinase-DNA ligase 4 complex | intracellular