QuickView for PSD95;jsessionid=9698ABE5C6D5B5E0DE5171EC49B549DF;jsessionid=836913C7E648495A58654D09F56CD2AD (gene)
- Gene Symbol:
- Dlg4
Mus musculus - Full name:
- discs large MAGUK scaffold protein 4
- Synonyms:
- Dlgh4, PSD-95, PSD95, SAP90, SAP90A, disks large homolog 4, PSD-95 alpha 2b, PSD-95 beta, SAP-90, discs large homolog 4, discs, large homolog 4, postsynaptic density protein 95, synapse-associated protein 90
- Genomic Location:
- Chr 11: 69832366-69858270
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
structural molecule activity | kinase binding | beta-2 adrenergic receptor binding | D1 dopamine receptor binding | protein kinase binding | enzyme binding | protein-containing complex binding | signaling receptor binding | neurexin family protein binding | adrenergic receptor binding | protein domain specific binding | frizzled binding | cytoskeletal protein binding | kinesin binding | dopamine receptor binding | scaffold protein binding | neuroligin family protein binding | protein binding | protein phosphatase binding | G-protein coupled receptor binding | PDZ domain binding | phosphatase binding | P2Y1 nucleotide receptor binding | acetylcholine receptor binding | protein C-terminus binding | glutamate receptor binding | ionotropic glutamate receptor binding | beta-1 adrenergic receptor binding
GO Biological Process
negative regulation of receptor internalization | cell morphogenesis | dendritic spine development | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cell development | regulation of localization | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | response to potassium ion | social behavior | response to metal ion | cell differentiation | nervous system development | response to drug | AMPA glutamate receptor clustering | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | establishment or maintenance of apical/basal cell polarity | generation of neurons | membrane organization | neuromuscular process controlling balance | positive regulation of neurological system process | cellular process | localization | cellular homeostasis | cell projection morphogenesis | neurotransmitter-gated ion channel clustering | exploration behavior | negative regulation of receptor-mediated endocytosis | positive regulation of synaptic transmission | chemical synaptic transmission | neuron development | regulation of neuronal synaptic plasticity | dendritic spine organization | cellular response to potassium ion | positive regulation of protein kinase activity | macromolecule localization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | response to inorganic substance | negative regulation of cellular metabolic process | regulation of behavior | regulation of neurological system process | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | cellular component organization | calcium ion homeostasis | cellular response to metal ion | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | response to cocaine | postsynaptic neurotransmitter receptor diffusion trapping | regulation of receptor internalization | receptor clustering | regulation of neurotransmitter receptor activity | cellular response to inorganic substance | cellular localization | negative regulation of transport | negative regulation of metabolic process | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | metal ion homeostasis | regulation of membrane potential | response to nitrogen compound | regulation of long-term neuronal synaptic plasticity | regulation of protein tyrosine kinase activity | system development | regulation of signal transduction | modulation of excitatory postsynaptic potential | positive regulation of neuron projection development | multicellular organism development | regulation of catalytic activity | regulation of phosphorylation | localization within membrane | regulation of receptor-mediated endocytosis | regulation of neuron differentiation | regulation of grooming behavior | protein localization to membrane | nervous system process | synaptic signaling | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | response to ammonium ion | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of cell projection organization | synapse organization | positive regulation of neuron projection arborization | positive regulation of cell differentiation | locomotory behavior | regulation of cellular protein metabolic process | response to xenobiotic stimulus | cell morphogenesis involved in differentiation | cation homeostasis | establishment or maintenance of cell polarity | receptor localization to synapse | glutamate receptor clustering | protein localization to synapse | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | protein-containing complex localization | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | postsynaptic membrane organization | synaptic vesicle maturation | positive regulation of molecular function | neuron differentiation | regulation of signaling receptor activity | protein-containing complex assembly | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | anatomical structure development | positive regulation of neurogenesis | negative regulation of endocytosis | cell projection organization | positive regulation of cell development | developmental maturation | establishment or maintenance of epithelial cell apical/basal polarity | cellular protein localization | regulation of vesicle-mediated transport | chemical homeostasis | behavior | cell adhesion | dendritic spine morphogenesis | neuron projection development | vocalization behavior | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | regulation of ion transmembrane transport | establishment of protein localization | vesicle organization | cell-cell adhesion | positive regulation of excitatory postsynaptic potential | dendrite morphogenesis | regulation of cell communication | signaling | response to organic cyclic compound | neuromuscular process | cell development | regulation of endocytosis | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | anatomical structure morphogenesis | cellular macromolecule localization | regulation of NMDA receptor activity | dendrite development | regulation of nervous system development | regulation of developmental process | regulation of ion transport | developmental process | organelle organization | regulation of transport | regulation of cation channel activity | response to organonitrogen compound | locomotory exploration behavior | cellular metal ion homeostasis | regulation of glutamate receptor signaling pathway | response to anesthetic | positive regulation of metabolic process | regulation of synaptic plasticity | positive regulation of neuron differentiation | regulation of cell projection organization | divalent inorganic cation homeostasis | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
dendritic spine | exocytic vesicle | integral component of membrane | cytoplasmic side of plasma membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | extrinsic component of membrane | potassium channel complex | somatodendritic compartment | neuromuscular junction | postsynaptic specialization membrane | cytoplasmic vesicle | cell | cytoplasmic side of membrane | plasma membrane protein complex | extrinsic component of plasma membrane | intrinsic component of membrane | synaptic membrane | cytoplasm | cortical cytoskeleton | dendrite cytoplasm | cerebellar mossy fiber | intracellular organelle | receptor complex | endoplasmic reticulum | dendritic tree | main axon | presynapse | protein-containing complex | cell projection | secretory vesicle | postsynaptic membrane | endomembrane system | neuron spine | postsynapse | plasma membrane bounded cell projection cytoplasm | plasma membrane | extrinsic component of cytoplasmic side of plasma membrane | postsynaptic density membrane | vesicle | transport vesicle | postsynaptic density | asymmetric synapse | voltage-gated potassium channel complex | cytoplasmic region | integral component of plasma membrane | synaptic vesicle | juxtaparanode region of axon | cell cortex | membrane-bounded organelle | organelle | postsynaptic specialization | cell periphery | excitatory synapse | axon | basolateral plasma membrane | ionotropic glutamate receptor complex | transmembrane transporter complex | neuron projection terminus | cation channel complex | ion channel complex | intracellular vesicle | cytoskeleton | intracellular | cell junction | membrane | AMPA glutamate receptor complex | intrinsic component of plasma membrane
