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QuickView for PTC;jsessionid=7D76EEE52B588B5B9DE3B0F5142DAE02;jsessionid=561BDCA7FD184137CC8919B5479B3C2F (gene)


Gene Symbol:
Ptch1 Rattus norvegicus Rattus norvegicus
Full name:
patched 1
Synonyms:
Ptch, Ptch2, protein patched homolog 1, patched homolog 2
Genomic Location:
Chr 17: 7088234-7142457
Description:
human homolog acts as a receptor for sonic hedgehog
Orthologs:
Homo sapiens Mus musculus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AACTTT_UNKNOWN RSRFC4_01 SOX5_01 EVI1_04 MZF1_02 IK1_01 IK2_01 CEBPB_01 MYCMAX_02 NFY_Q6


Transcripts Names
NM_053566
Protein Names
Q6UY90



GO Molecular Function

cyclin binding | patched binding | transmembrane signaling receptor activity | protein-containing complex binding | lipid binding | sterol binding | signaling receptor binding | hedgehog family protein binding | carbohydrate derivative binding | alcohol binding | anion binding | smoothened binding | signaling receptor activity | ion binding | organic cyclic compound binding | cholesterol binding | heparin binding | protein binding | hedgehog receptor activity | G-protein coupled receptor binding | glycosaminoglycan binding | steroid binding | small molecule binding

GO Biological Process

brain development | limb development | cell morphogenesis | positive regulation of macromolecule biosynthetic process | negative regulation of cell division | pharyngeal system development | neuron projection morphogenesis | developmental process involved in reproduction | protein localization to cell periphery | regulation of cholesterol transport | proteolysis | regulation of localization | mammary gland duct morphogenesis | morphogenesis of an epithelium | cell proliferation involved in kidney development | cell proliferation involved in metanephros development | spinal cord motor neuron differentiation | response to hormone | negative regulation of cellular process | neural tube patterning | positive regulation of developmental process | protein processing | negative regulation of RNA biosynthetic process | embryonic appendage morphogenesis | cell differentiation | nervous system development | response to drug | cell part morphogenesis | neurogenesis | glucose homeostasis | generation of neurons | regulation of lipid transport | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | cell fate specification | localization | cell projection morphogenesis | epithelial tube morphogenesis | limb morphogenesis | commissural neuron axon guidance | heart morphogenesis | negative regulation of signaling | neuron development | negative regulation of developmental growth | positive regulation of cholesterol efflux | central nervous system neuron differentiation | reproductive system development | response to estradiol | negative regulation of nucleic acid-templated transcription | renal tubule morphogenesis | macromolecule localization | branching involved in ureteric bud morphogenesis | axon guidance | regulation of cell cycle | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | response to inorganic substance | regulation of smoothened signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | hindlimb morphogenesis | regeneration | regulation of cellular process | regulation of osteoblast differentiation | cellular response to lipid | regulation of metabolic process | hepaticobiliary system development | epithelium development | cellular component organization | regulation of cell division | urogenital system development | mammary gland morphogenesis | nephron tubule morphogenesis | head development | response to stimulus | cell morphogenesis involved in neuron differentiation | embryonic limb morphogenesis | embryonic epithelial tube formation | gland morphogenesis | neuron projection guidance | positive regulation of epidermal cell differentiation | regulation of cell proliferation | tube morphogenesis | regulation of epithelial cell differentiation | epithelial tube formation | reproduction | cellular localization | response to alcohol | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | dorsal/ventral pattern formation | kidney development | embryo development | regulation of nucleic acid-templated transcription | locomotion | negative regulation of osteoblast differentiation | system development | ventral spinal cord development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | ureteric bud development | negative regulation of growth | keratinocyte proliferation | multicellular organism development | mammary gland development | cellular response to cholesterol | kidney morphogenesis | regulation of ossification | protein localization to plasma membrane | neural plate pattern specification | regulation of gene expression | kidney epithelium development | protein localization to membrane | axon development | neural tube closure | response to lipid | embryonic axis specification | regulation of epidermis development | positive regulation of cellular metabolic process | cellular response to sterol | animal organ morphogenesis | neural plate axis specification | liver development | epidermal cell fate specification | regulation of nitrogen compound metabolic process | response to cholesterol | negative regulation of DNA-binding transcription factor activity | neural tube formation | regulation of transcription by RNA polymerase II | axonogenesis | positive regulation of cell differentiation | epidermal cell differentiation | positive regulation of cholesterol transport | cell proliferation | neural tube development | cell differentiation involved in kidney development | mesonephric epithelium development | negative regulation of multicellular organism growth | protein maturation | epidermis development | positive regulation of lipid localization | cell morphogenesis involved in differentiation | mesonephros development | chordate embryonic development | cell communication | regulation of cellular metabolic process | liver regeneration | metanephros development | renal tubule development | dorsal/ventral neural tube patterning | heart development | homeostatic process | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | renal system development | positive regulation of transport | response to retinoic acid | embryonic morphogenesis | regulation of mitotic cell cycle | nephron development | neuron differentiation | ureteric bud morphogenesis | negative regulation of epithelial cell proliferation | protein metabolic process | regionalization | axis specification | regulation of growth | response to organic substance | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | epithelial cell proliferation | response to mechanical stimulus | negative regulation of ossification | regulation of DNA-binding transcription factor activity | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | cellular protein localization | chemical homeostasis | morphogenesis of embryonic epithelium | neuron projection development | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | nephron morphogenesis | animal organ development | gene expression | neural plate development | mammary gland epithelium development | morphogenesis of a branching epithelium | smoothened signaling pathway | anatomical structure formation involved in morphogenesis | cell differentiation in spinal cord | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | somite development | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | regulation of developmental growth | response to chlorate | protein localization | regulation of epithelial cell proliferation | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | cellular macromolecule localization | reproductive structure development | regulation of developmental process | regulation of cholesterol efflux | developmental process | negative regulation of smoothened signaling pathway | positive regulation of epithelial cell differentiation | negative regulation of transcription by RNA polymerase II | tube development | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | cell fate determination | tube closure | epithelial cell differentiation | positive regulation of epidermis development | tube formation | mammary gland epithelial cell differentiation | central nervous system development | smoothened signaling pathway involved in dorsal/ventral neural tube patterning | spinal cord development | in utero embryonic development | positive regulation of metabolic process | positive regulation of lipid transport | cellular response to organic substance | regulation of protein localization | circulatory system development | carbohydrate homeostasis | chemotaxis | nephron tubule development | negative regulation of cell differentiation | regulation of epidermal cell differentiation | signal transduction | regulation of signaling | animal organ regeneration | mesonephric tubule development | positive regulation of gene expression | embryonic pattern specification | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell | distal axon | dendrite terminus | intrinsic component of membrane | cytoplasm | intracellular organelle | membrane microdomain | dendritic tree | Golgi apparatus | cell projection | endomembrane system | postsynapse | plasma membrane | midbody | cilium | membrane raft | perinuclear region of cytoplasm | postsynaptic density | asymmetric synapse | site of polarized growth | axonal growth cone | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cell periphery | axon | growth cone | plasma membrane raft | dendritic growth cone | intracellular | caveola | membrane