QuickView for PTGS1;jsessionid=79EC64B502002DEF7CF0B278FB5AC4D5;jsessionid=089762B374A73D3A8540669045680BD1 (gene)

Gene Symbol:

Ptgs1 Mus musculus

Full name:

prostaglandin-endoperoxide synthase 1

Synonyms:

COX1, Cox-1, Cox-3, PGHS-1, PHS 1, Pghs1, prostaglandin G/H synthase 1, PGH synthase 1, cyclooxygenase-1, prostaglandin H2 synthase 1

Genomic Location:

Chr 2: 36085946-36107789

Description:

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein...

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This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SMTTTTGT_UNKNOWN ,  TGCTGAY_UNKNOWN ,  RGAGGAARY_PU1_Q6

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