QuickView for PTPN11;jsessionid=56A5863822587C27E41D5C31B2F8536F;jsessionid=1F64CC0D6266A65203E85E1EA5A6B606 (gene)
- Gene Symbol:
- PTPN11
Gallus gallus - Full name:
- protein tyrosine phosphatase, non-receptor type 11
- Synonyms:
- SYP
- Genomic Location:
- Chr 15: 6487260-6515631
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
protein phosphorylated amino acid binding | kinase binding | hormone receptor binding | protein kinase binding | receptor tyrosine kinase binding | enzyme binding | protein-containing complex binding | phosphotyrosine residue binding | phosphatase activity | signaling receptor binding | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | signaling adaptor activity | protein binding, bridging | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | protein tyrosine kinase binding | molecular adaptor activity | peptide hormone receptor binding | cell adhesion molecule binding | phosphoprotein binding | protein binding | insulin receptor binding | phosphoric ester hydrolase activity | SH3/SH2 adaptor activity | non-membrane spanning protein tyrosine phosphatase activity
GO Biological Process
regulation of ERK1 and ERK2 cascade | brain development | cell morphogenesis | regulation of intracellular protein transport | protein dephosphorylation | cell motility | neuron projection morphogenesis | developmental process involved in reproduction | regulation of cellular localization | negative regulation of peptide secretion | homeostasis of number of cells within a tissue | regulation of localization | response to hormone | myeloid cell differentiation | negative regulation of cellular process | integrin-mediated signaling pathway | regulation of MAP kinase activity | bone development | cell differentiation | nervous system development | multicellular organism growth | organ growth | cerebellum morphogenesis | epithelial cell migration | cell part morphogenesis | neurogenesis | glucose homeostasis | positive regulation of phosphate metabolic process | negative regulation of protein secretion | regulation of peptide hormone secretion | generation of neurons | tissue homeostasis | regulation of lipid transport | hormone-mediated signaling pathway | cellular process | regulation of glucose import | localization | cell projection morphogenesis | regulation of growth hormone secretion | negative regulation of signaling | developmental growth | neuron development | reproductive system development | epithelium migration | triglyceride metabolic process | immune system development | multicellular organismal reproductive process | negative regulation of glucocorticoid secretion | positive regulation of protein kinase activity | negative regulation of secretion | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | myeloid cell development | negative regulation of cortisol secretion | negative regulation of hormone secretion | regulation of protein export from nucleus | negative regulation of establishment of protein localization | anatomical structure homeostasis | regulation of cellular process | regulation of metabolic process | head morphogenesis | gliogenesis | regulation of protein complex assembly | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | negative regulation of response to drug | ephrin receptor signaling pathway | cellular component organization | cellular lipid metabolic process | phosphatase activity | head development | regulation of peptide secretion | response to stimulus | negative regulation of protein transport | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | metencephalon development | regulation of insulin secretion | positive regulation of protein metabolic process | negative regulation of cell adhesion | response to stress | negative regulation of growth hormone secretion | regulation of response to drug | multicellular organismal homeostasis | positive regulation of glucose import | intestinal epithelial cell migration | reproduction | positive regulation of hormone secretion | negative regulation of transport | ERBB signaling pathway | regulation of protein transport | positive regulation of protein serine/threonine kinase activity | platelet formation | hemopoiesis | protein modification process | regulation of peptide transport | regulation of cell adhesion | macromolecule modification | protein tyrosine phosphatase activity | activation of protein kinase activity | regulation of intracellular transport | locomotion | cellular response to hormone stimulus | signaling adaptor activity | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | cell migration | regulation of MAPK cascade | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of catalytic activity | cerebellum development | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of glucose import in response to insulin stimulus | positive regulation of cell cycle | positive regulation of mitotic cell cycle | platelet-derived growth factor receptor signaling pathway | axon development | positive regulation of secretion | cellular response to stress | cell cycle | platelet morphogenesis | regulation of glucose import in response to insulin stimulus | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | phosphoprotein phosphatase activity | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | axonogenesis | homeostasis of number of cells | positive regulation of glucose transmembrane transport | regulation of cellular protein metabolic process | neurotrophin signaling pathway | glial cell differentiation | negative regulation of peptide hormone secretion | hindbrain development | regulation of cell adhesion mediated by integrin | megakaryocyte differentiation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | sensory organ development | positive regulation of cellular response to insulin stimulus | microvillus organization | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | astrocyte differentiation | cerebellar cortex morphogenesis | regulation of endocrine process | regulation of protein metabolic process | positive regulation of signal transduction | inner ear development | heart development | homeostatic process | regulation of protein phosphorylation | glycerolipid metabolic process | positive regulation of transport | genitalia development | regulation of mitotic cell cycle | positive regulation of molecular function | regulation of nucleocytoplasmic transport | cellular response to epidermal growth factor stimulus | neuron differentiation | multicellular organism reproduction | activation of MAPK activity | negative regulation of lipid transport | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | regulation of growth | response to organic substance | neutral lipid metabolic process | neurotrophin TRK receptor signaling pathway | regulation of kinase activity | abortive mitotic cell cycle | regulation of intracellular signal transduction | face morphogenesis | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | cell projection organization | metabolic process | ear development | cerebellar cortex development | hindbrain morphogenesis | chemical homeostasis | regulation of secretion | neuron projection development | atrioventricular canal development | organic substance metabolic process | regulation of glucose transmembrane transport | animal organ development | regulation of protein secretion | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | SH3/SH2 adaptor activity | Bergmann glial cell differentiation | positive regulation of MAPK cascade | response to epidermal growth factor | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | cerebellar cortex formation | regulation of cell communication | dephosphorylation | negative regulation of insulin secretion | signaling | cell development | regulation of developmental growth | positive regulation of phosphorylation | cellular protein metabolic process | hormone metabolic process | anatomical structure morphogenesis | positive regulation of MAP kinase activity | reproductive structure development | regulation of developmental process | developmental process | cellular protein modification process | regulation of transport | non-membrane spanning protein tyrosine phosphatase activity | negative regulation of cell adhesion mediated by integrin | peptidyl-tyrosine dephosphorylation | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | skeletal system development | immune system process | cellular metabolic process | body morphogenesis | hematopoietic or lymphoid organ development | ameboidal-type cell migration | cellular response to organic substance | regulation of protein localization | sex differentiation | megakaryocyte development | DNA damage checkpoint | cell cycle checkpoint | acylglycerol metabolic process | circulatory system development | carbohydrate homeostasis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | face development | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | intracellular
