QuickView for ROCK1;jsessionid=0D9D71E158B70A7A18432922EEB22062;jsessionid=3907F1BCF0BE53C465F2822E946E0B48 (gene)
- Gene Symbol:
- ROCK1
Canis lupus familiaris - Full name:
- Rho-associated, coiled-coil containing protein kinase 1
- Synonyms:
- N/A
- Genomic Location:
- Chr 7: 69841453-70041152
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
GTPase binding | Rho GTPase binding | cation binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | Ras GTPase binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | small GTPase binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | GTP-Rho binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
negative regulation of amyloid-beta formation | regulation of supramolecular fiber organization | cell morphogenesis | regulation of muscle system process | apical constriction | regulation of dephosphorylation | actin filament-based process | myoblast migration | positive regulation of cellular component organization | cell motility | regulation of neurogenesis | neuron projection morphogenesis | positive regulation of adherens junction organization | protein localization to cell periphery | regulation of cellular localization | intracellular signal transduction | regulation of cell development | regulation of localization | neuron projection arborization | regulation of programmed cell death | actin cytoskeleton organization | regulation of autophagy | response to hormone | negative regulation of neuron death | negative regulation of cellular process | regulation of phosphatase activity | cell differentiation | nervous system development | regulation of angiotensin-activated signaling pathway | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | generation of neurons | regulation of neuron death | cellular process | localization | cell projection morphogenesis | neuron development | macromolecule localization | negative regulation of apoptotic process | membrane docking | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of myosin-light-chain-phosphatase activity | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of binding | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | actin filament-based movement | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | leukocyte tethering or rolling | regulation of metabolic process | regulation of bicellular tight junction assembly | cortical actin cytoskeleton organization | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | negative regulation of phosphatase activity | epithelium development | cellular component organization | actin-mediated cell contraction | response to transforming growth factor beta | regulation of establishment of cell polarity | regulation of vasculature development | response to stimulus | positive regulation of protein metabolic process | negative regulation of angiogenesis | response to peptide | epithelial cell development | regulation of epithelial cell differentiation | protein serine/threonine kinase activity | cellular localization | negative regulation of metabolic process | cellular component assembly | protein modification process | regulation of cell adhesion | macromolecule modification | negative regulation of amyloid precursor protein catabolic process | epithelial cell morphogenesis | positive regulation of cell-matrix adhesion | regulation of establishment or maintenance of cell polarity | leukocyte migration | locomotion | response to nitrogen compound | negative regulation of neuron apoptotic process | positive regulation of cell junction assembly | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | regulation of adherens junction organization | regulation of actin cytoskeleton organization | multicellular organism development | negative regulation of catalytic activity | cell migration | regulation of MAPK cascade | phosphorus metabolic process | regulation of actin filament organization | regulation of catalytic activity | regulation of actomyosin structure organization | regulation of phosphorylation | protein localization to plasma membrane | regulation of neuron differentiation | regulation of gene expression | protein localization to membrane | regulation of epidermis development | cell projection assembly | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of keratinocyte differentiation | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | positive regulation of intracellular signal transduction | negative regulation of binding | regulation of cellular protein metabolic process | phosphorylation | positive regulation of amyloid-beta clearance | regulation of synaptic vesicle endocytosis | protein phosphorylation | regulation of amyloid precursor protein catabolic process | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | negative regulation of protein dephosphorylation | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | regulation of neuron apoptotic process | regulation of establishment of endothelial barrier | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | response to angiotensin | neuron differentiation | negative regulation of bicellular tight junction assembly | protein metabolic process | muscle cell migration | regulation of cardiac muscle hypertrophy | positive regulation of focal adhesion assembly | positive regulation of protein modification process | response to organic substance | leukocyte adhesion to vascular endothelial cell | Rho protein signal transduction | regulation of protein dephosphorylation | regulation of intracellular signal transduction | regulation of focal adhesion assembly | anatomical structure development | positive regulation of connective tissue replacement | leukocyte cell-cell adhesion | cell projection organization | metabolic process | negative regulation of programmed cell death | cellular protein localization | regulation of amyloid-beta clearance | regulation of tissue remodeling | regulation of vesicle-mediated transport | cell adhesion | protein kinase activity | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of myosin-light-chain-phosphatase activity | membrane to membrane docking | positive regulation of cell-substrate adhesion | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | cytoskeleton organization | positive regulation of autophagy | cell-cell adhesion | positive regulation of MAPK cascade | regulation of stress fiber assembly | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | signaling | regulation of protein binding | regulation of amyloid-beta formation | cell development | regulation of endocytosis | I-kappaB kinase/NF-kappaB signaling | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | negative regulation of phosphoprotein phosphatase activity | anatomical structure morphogenesis | cellular macromolecule localization | regulation of actin filament bundle assembly | positive regulation of tissue remodeling | regulation of synaptic vesicle recycling | bleb assembly | regulation of nervous system development | regulation of developmental process | regulation of G-protein coupled receptor protein signaling pathway | regulation of phosphoprotein phosphatase activity | kinase activity | developmental process | organelle organization | cellular protein modification process | cortical cytoskeleton organization | cellular extravasation | regulation of cell junction assembly | regulation of transport | negative regulation of vasculature development | Ras protein signal transduction | regulation of endothelial cell differentiation | response to organonitrogen compound | negative regulation of dephosphorylation | epithelial cell differentiation | negative regulation of hydrolase activity | positive regulation of metabolic process | regulation of actin filament-based process | immune system process | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | regulation of epidermal cell differentiation | regulation of cytoskeleton organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of cell-matrix adhesion | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
ruffle | cytoplasmic stress granule | cell | ribonucleoprotein granule | lamellipodium | cytoplasm | intracellular organelle | protein-containing complex | cell projection | plasma membrane | cell leading edge | ribonucleoprotein complex | organelle | cytoplasmic ribonucleoprotein granule | cell periphery | amyloid-beta complex | cytoskeleton | intracellular | membrane
