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QuickView for RhoA;jsessionid=30EC3C9A9CE6A0B87C7355B137247748;jsessionid=8FC52E476D04073062A3BCE74C0AC808 (gene)


Gene Symbol:
Rhoa Rattus norvegicus Rattus norvegicus
Full name:
ras homolog family member A
Synonyms:
Arha, Arha2, transforming protein RhoA, plysia ras-related homolog A2, ras homolog gene family, member A
Genomic Location:
Chr 16_random: 1010014-1044290
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Protein Names
P61589



GO Molecular Function

kinase binding | GDP binding | guanyl ribonucleotide binding | ribonucleoside binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | hydrolase activity | myosin binding | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | protein domain specific binding | cytoskeletal protein binding | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | Rho GDP-dissociation inhibitor binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | GDP-dissociation inhibitor binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

mitotic cytokinesis | mitotic cleavage furrow formation | negative regulation of phosphorylation | brain development | regulation of supramolecular fiber organization | purine ribonucleotide metabolic process | regulation of blood vessel diameter | cell morphogenesis | regulation of muscle system process | regulation of cell cycle process | forebrain radial glial cell differentiation | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | regulation of cysteine-type endopeptidase activity | positive regulation of blood circulation | actin filament-based process | microtubule cytoskeleton organization involved in mitosis | regulation of systemic arterial blood pressure by hormone | response to cytokine | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | response to lipopolysaccharide | muscle tissue development | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | regulation of localization | cellular response to progesterone stimulus | cell-substrate adhesion | actin filament bundle organization | morphogenesis of an epithelium | regulation of programmed cell death | T cell lineage commitment | actin cytoskeleton organization | regulation of osteoblast proliferation | regulation of immune system process | response to hormone | regulation of cell shape | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | negative regulation of cell migration involved in sprouting angiogenesis | positive regulation of lymphocyte activation | bone development | microtubule cytoskeleton organization | cell differentiation | regulation of T cell differentiation | nervous system development | regulation of smooth muscle contraction | response to drug | androgen receptor signaling pathway | regulation of sprouting angiogenesis | epithelial cell migration | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | establishment or maintenance of apical/basal cell polarity | generation of neurons | membrane organization | response to antibiotic | hormone-mediated signaling pathway | microtubule-based process | positive regulation of T cell differentiation | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | positive regulation of actin filament polymerization | lymphocyte differentiation | regulation of cell motility | localization | cell projection morphogenesis | epithelial tube morphogenesis | cytokinetic process | odontogenesis | forebrain cell migration | nucleotide metabolic process | negative regulation of signaling | neuron development | response to progesterone | cytoskeleton-dependent cytokinesis | epithelium migration | immune system development | ribose phosphate metabolic process | positive regulation of protein kinase activity | negative regulation of apoptotic process | response to hypoxia | regulation of proteolysis | nucleoside triphosphate metabolic process | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | ribonucleotide metabolic process | regulation of neuron projection development | positive regulation of cell division | spindle assembly | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regulation of oxidative phosphorylation | muscle structure development | positive regulation of vasoconstriction | cell junction assembly | skeletal muscle organ development | positive regulation of cytokinesis | negative regulation of cell motility | regulation of angiogenesis | morphogenesis of a polarized epithelium | regulation of cellular process | leukocyte activation | positive regulation of cell growth | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | gliogenesis | regulation of protein complex assembly | cellular response to molecule of bacterial origin | polarized epithelial cell differentiation | small GTPase mediated signal transduction | organic cyclic compound metabolic process | trabecula morphogenesis | positive regulation of translation | positive regulation of cellular protein metabolic process | epithelium development | cellular aromatic compound metabolic process | establishment of cell polarity | cellular component organization | negative regulation of nucleotide metabolic process | angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure | regulation of systemic arterial blood pressure mediated by a chemical signal | regulation of cell division | T cell activation | regulation of actin filament length | head development | regulation of vascular smooth muscle contraction | skeletal muscle satellite cell migration | regulation of vasculature development | response to stimulus | positive regulation of blood pressure | purine nucleotide metabolic process | wound healing, spreading of cells | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | mitotic spindle organization | negative regulation of cell adhesion | regulation of blood vessel size | regulation of modification of synaptic structure | response to stress | mitotic cytokinetic process | regulation of intracellular steroid hormone receptor signaling pathway | endothelial cell migration | positive regulation of T cell migration | skeletal muscle tissue development | posttranscriptional regulation of gene expression | regulation of cell proliferation | negative regulation of neuron projection development | positive regulation of actin filament bundle assembly | negative regulation of angiogenesis | tube morphogenesis | regulation of blood circulation | positive regulation of cell-cell adhesion | positive regulation of cysteine-type endopeptidase activity | response to glucose | telencephalon cell migration | supramolecular fiber organization | positive regulation of cell activation | response to alcohol | positive regulation of proteolysis | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | positive regulation of lipase activity | positive regulation of T cell activation | cellular response to organic cyclic compound | blood circulation | negative regulation of metabolic process | regulation of cellular component size | positive regulation of protein serine/threonine kinase activity | hemopoiesis | cellular component assembly | steroid hormone mediated signaling pathway | regulation of synapse structure or activity | regulation of cell adhesion | purine nucleoside metabolic process | negative regulation of reactive oxygen species biosynthetic process | epiboly | regulation of lymphocyte differentiation | stress-activated protein kinase signaling cascade | response to ethanol | positive regulation of stress fiber assembly | negative regulation of blood vessel diameter | regulation of nucleic acid-templated transcription | leukocyte differentiation | establishment or maintenance of actin cytoskeleton polarity | locomotion | response to nitrogen compound | negative regulation of neuron apoptotic process | organelle assembly | cellular response to hormone stimulus | cleavage furrow formation | response to external biotic stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | endothelium development | cellular response to chemokine | negative regulation of phosphate metabolic process | regulation of actin cytoskeleton organization | multicellular organism development | negative regulation of ATP metabolic process | cell migration | positive regulation of lymphocyte differentiation | regulation of peptidase activity | phosphorus metabolic process | response to amino acid | positive regulation of organelle assembly | regulation of actin filament organization | actin filament organization | positive regulation of podosome assembly | regulation of muscle contraction | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of actomyosin structure organization | regulation of phosphorylation | positive regulation of lymphocyte migration | wound healing | regulation of T cell activation | telencephalon development | positive regulation of cell cycle | positive regulation of alpha-beta T cell differentiation | regulation of neuron differentiation | regulation of gene expression | response to ketone | cellular response to stress | response to lipid | cell cycle | regulation of blood pressure | alpha-beta T cell lineage commitment | regulation of systemic arterial blood pressure by renin-angiotensin | organophosphate metabolic process | regulation of systemic arterial blood pressure | nucleoside metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | animal organ morphogenesis | regulation of synapse organization | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | regulation of cysteine-type endopeptidase activity involved in apoptotic process | small molecule metabolic process | apical junction assembly | establishment or maintenance of monopolar cell polarity | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | response to corticosteroid | regulation of cellular component movement | regulation of transcription by RNA polymerase II | alpha-beta T cell differentiation | actin filament bundle assembly | morphogenesis of an epithelial sheet | regulation of cell migration involved in sprouting angiogenesis | radial glial cell differentiation | positive regulation of hydrolase activity | positive regulation of cell differentiation | regulation of endothelial cell migration | nucleobase-containing small molecule metabolic process | positive regulation of cell migration | negative regulation of intracellular steroid hormone receptor signaling pathway | cellular response to cytokine stimulus | negative regulation of epithelial cell migration | cell division | regulation of cellular protein metabolic process | negative regulation of cell-substrate adhesion | glial cell differentiation | vasoconstriction | cytokinesis | actomyosin structure organization | positive regulation of endopeptidase activity | positive regulation of neuron death | response to toxic substance | regulation of systemic arterial blood pressure by endothelin | cerebral cortex cell migration | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | establishment or maintenance of cell polarity | regulation of leukocyte migration | phosphate-containing compound metabolic process | cellular response to drug | response to bacterium | negative regulation of blood vessel endothelial cell migration | striated muscle tissue development | endocrine process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of smooth muscle contraction | GTP metabolic process | regulation of cytokinesis | regulation of neuron apoptotic process | regulation of actin filament polymerization | negative regulation of oxidative phosphorylation | regulation of alpha-beta T cell differentiation | regulation of T cell migration | contractile actin filament bundle assembly | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | response to monosaccharide | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | regulation of tube size | cerebral cortex development | negative regulation of sprouting angiogenesis | ossification involved in bone maturation | positive regulation of systemic arterial blood pressure | regulation of microtubule-based process | lymphocyte activation | positive regulation of molecular function | neuron differentiation | T cell differentiation | regulation of podosome assembly | positive regulation of protein modification process | regulation of growth | T cell selection | response to organic substance | negative regulation of cell projection organization | Roundabout signaling pathway | tissue morphogenesis | regulation of hemopoiesis | Rho protein signal transduction | regulation of kinase activity | response to wounding | response to mechanical stimulus | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of vasoconstriction | apolipoprotein A-I-mediated signaling pathway | regulation of neural precursor cell proliferation | nuclear division | endothelial tube morphogenesis | cell projection organization | metabolic process | positive regulation of cell development | cell fate commitment | positive regulation of supramolecular fiber organization | negative regulation of I-kappaB kinase/NF-kappaB signaling | cell-cell junction assembly | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | developmental maturation | establishment or maintenance of epithelial cell apical/basal polarity | negative regulation of programmed cell death | negative regulation of cell size | regulation of tube diameter | membrane invagination | actin cytoskeleton reorganization | forebrain generation of neurons | positive regulation of cell death | cell adhesion | establishment of monopolar cell polarity | nucleobase-containing compound metabolic process | neuron projection development | positive regulation of muscle contraction | positive regulation of cellular component biogenesis | organic substance metabolic process | beta selection | negative regulation of biosynthetic process | animal organ development | forebrain development | negative regulation of neuron differentiation | pallium development | establishment of epithelial cell polarity | endothelial tube lumen extension | regulation of cell activation | negative regulation of cellular component movement | positive regulation of leukocyte migration | positive regulation of programmed cell death | positive regulation of kinase activity | alpha-beta T cell activation | regulation of ATP metabolic process | regulation of phosphate metabolic process | cytoskeleton organization | cellular response to steroid hormone stimulus | renal system process | mitotic nuclear division | cell activation | intracellular receptor signaling pathway | regulation of reactive oxygen species biosynthetic process | regulation of stress fiber assembly | regulation of dendrite development | regulation of epithelial cell migration | establishment of apical/basal cell polarity | bone maturation | regulation of cell communication | regulation of blood vessel endothelial cell migration | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of growth | regulation of transcription, DNA-templated | cell-matrix adhesion | response to organic cyclic compound | cell development | positive regulation of phosphorylation | regulation of cell size | anatomical structure morphogenesis | regulation of endopeptidase activity | stress fiber assembly | regulation of actin filament bundle assembly | response to biotic stimulus | regulation of nervous system development | regulation of developmental process | regulation of ion transport | renal system process involved in regulation of systemic arterial blood pressure | developmental process | organelle organization | positive regulation of alpha-beta T cell activation | positive regulation of cell cycle process | regulation of cell growth | regulation of calcium ion transport | intracellular steroid hormone receptor signaling pathway | negative chemotaxis | tube development | carbohydrate derivative metabolic process | regulation of transport | regulation of reactive oxygen species metabolic process | regulation of cell-cell adhesion | positive regulation of protein polymerization | negative regulation of vasculature development | Ras protein signal transduction | negative regulation of endothelial cell migration | response to organonitrogen compound | epithelial cell differentiation | establishment or maintenance of cytoskeleton polarity | heterocycle metabolic process | mitotic spindle assembly | central nervous system development | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | regulation of actin filament-based process | ossification | positive regulation of neuron differentiation | regulation of cell projection organization | skeletal system development | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | response to carbohydrate | response to steroid hormone | regulation of organelle assembly | establishment of epithelial cell apical/basal polarity | regulation of translation | regulation of blood vessel diameter by renin-angiotensin | negative regulation of cell death | negative regulation of cell development | spindle organization | chemotaxis | negative regulation of locomotion | positive regulation of leukocyte cell-cell adhesion | positive regulation of vascular smooth muscle contraction | regulation of microtubule cytoskeleton organization | regulation of lymphocyte migration | regulation of I-kappaB kinase/NF-kappaB signaling | negative regulation of cell differentiation | regulation of cellular component organization | muscle organ development | regulation of cytoskeleton organization | response to other organism | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | cellular response to lipopolysaccharide | negative regulation of neurogenesis | multicellular organismal process | cell-cell junction organization | regulation of phosphorus metabolic process

GO Cellular Component

dendritic spine | cleavage furrow | cytoplasmic side of plasma membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | extrinsic component of membrane | ruffle | somatodendritic compartment | cell projection membrane | cytoplasmic vesicle | cell | cytoplasmic side of membrane | extrinsic component of plasma membrane | ruffle membrane | lamellipodium | cytoplasm | intracellular organelle | dendritic tree | leading edge membrane | cell-cell junction | cell projection | endomembrane system | neuron spine | postsynapse | plasma membrane | extrinsic component of cytoplasmic side of plasma membrane | midbody | cell leading edge | vesicle | cytoplasmic region | endosome | cell cortex | membrane-bounded organelle | apical junction complex | nucleus | organelle | cell division site | cell periphery | axon | cytosol | intracellular vesicle | cytoskeleton | intracellular | cell junction | membrane