QuickView for SCA3;jsessionid=363E2F6ECB1E1A0493C946FC33FB0081;jsessionid=832CDBF413F9EEC06893587DFD9282A0 (gene)
- Gene Symbol:
- ATXN3
Bos taurus - Full name:
- ataxin 3
- Synonyms:
- MGC165708
- Genomic Location:
- Chr 21: 57269545-57289440
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Gallus gallus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
Lys48-specific deubiquitinase activity | enzyme binding | thiol-dependent ubiquitinyl hydrolase activity | hydrolase activity | cysteine-type peptidase activity | catalytic activity | ubiquitin-like protein ligase binding | ATPase binding | thiol-dependent ubiquitin-specific protease activity | Lys63-specific deubiquitinase activity | protein binding | ubiquitinyl hydrolase activity | ubiquitin protein ligase binding | peptidase activity
GO Biological Process
protein modification by small protein removal | actin filament-based process | response to endoplasmic reticulum stress | proteolysis | actin cytoskeleton organization | microtubule cytoskeleton organization | response to misfolded protein | positive regulation of protein catabolic process | microtubule-based process | cellular process | organic substance catabolic process | localization | proteolysis involved in cellular protein catabolic process | exploration behavior | macromolecule localization | regulation of proteolysis | Lys48-specific deubiquitinase activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | response to topologically incorrect protein | cellular component organization | protein localization to cytosolic proteasome complex involved in ERAD pathway | protein deubiquitination | cellular response to topologically incorrect protein | thiol-dependent ubiquitinyl hydrolase activity | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | response to stress | regulation of response to endoplasmic reticulum stress | positive regulation of proteolysis involved in cellular protein catabolic process | cellular protein catabolic process | response to temperature stimulus | positive regulation of proteolysis | proteasomal protein catabolic process | protein K48-linked deubiquitination | protein modification process | regulation of cell adhesion | macromolecule modification | cysteine-type peptidase activity | regulation of cellular response to stress | response to nitrogen compound | nitrogen compound metabolic process | cellular response to stress | protein catabolic process | cellular response to heat | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | thiol-dependent ubiquitin-specific protease activity | regulation of cellular metabolic process | regulation of protein metabolic process | proteasome-mediated ubiquitin-dependent protein catabolic process | Lys63-specific deubiquitinase activity | ERAD pathway | protein metabolic process | protein K63-linked deubiquitination | response to organic substance | cellular macromolecule catabolic process | metabolic process | regulation of protein catabolic process | protein quality control for misfolded or incompletely synthesized proteins | regulation of proteasomal protein catabolic process | intermediate filament-based process | behavior | organic substance metabolic process | regulation of ERAD pathway | response to heat | protein modification by small protein conjugation or removal | cytoskeleton organization | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | protein localization | cellular protein metabolic process | positive regulation of ERAD pathway | organelle organization | cellular protein modification process | intermediate filament cytoskeleton organization | response to organonitrogen compound | positive regulation of metabolic process | cellular response to misfolded protein | cellular metabolic process | peptidase activity | cellular response to organic substance | modification-dependent protein catabolic process | monoubiquitinated protein deubiquitination | macromolecule metabolic process | positive regulation of response to endoplasmic reticulum stress
GO Cellular Component
nuclear inclusion body | mitochondrial matrix | intracellular membrane-bounded organelle | organelle membrane | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | inclusion body | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | cell periphery | membrane-enclosed lumen | mitochondrial membrane | cytosol | intracellular | membrane
