QuickView for SCN5A;jsessionid=8D857E12124C79A8310A471B97D36743;jsessionid=2D91B7B75116A2354E6662789285160A (gene)
- Gene Symbol:
- Scn5a
Mus musculus - Full name:
- sodium channel, voltage-gated, type V, alpha
- Synonyms:
- Nav1.5, Nav1.5c, SkM1, SkM2, mH1, sodium channel protein type 5 subunit alpha, sodium channel protein cardiac muscle subunit alpha, sodium channel protein type V subunit alpha, sodium channel, voltage-gated, type V, alpha polypeptide, voltage-gated sodium channel Nav1.5 variant a, voltage-gated sodium channel Nav1.5 variant b, voltage-gated sodium channel subunit alpha Nav1.5
- Genomic Location:
- Chr 9: 119392529-119488134
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-200b , Predicted Gene Targets for miR-214 , Predicted Gene Targets for miR-219 , Predicted Gene Targets for miR-369-3p , Predicted Gene Targets for miR-378* , Predicted Gene Targets for miR-448 , Predicted Gene Targets for miR-374
GO Molecular Function
kinase binding | voltage-gated ion channel activity | voltage-gated sodium channel activity involved in AV node cell action potential | passive transmembrane transporter activity | voltage-gated sodium channel activity involved in SA node cell action potential | protein kinase binding | enzyme binding | voltage-gated sodium channel activity | transmembrane transporter activity | ion gated channel activity | growth factor binding | ion channel binding | fibroblast growth factor binding | protein domain specific binding | ubiquitin-like protein ligase binding | cytoskeletal protein binding | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | scaffold protein binding | ankyrin binding | protein binding | ubiquitin protein ligase binding | metal ion transmembrane transporter activity | nitric-oxide synthase binding | voltage-gated sodium channel activity involved in Purkinje myocyte action potential | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calmodulin binding | ion channel activity | voltage-gated sodium channel activity involved in bundle of His cell action potential | substrate-specific channel activity
GO Biological Process
positive regulation of heart contraction | positive regulation of action potential | regulation of muscle system process | regulation of ventricular cardiac muscle cell membrane repolarization | heart process | positive regulation of blood circulation | actin filament-based process | regulation of localization | regulation of sodium ion transport | regulation of ventricular cardiac muscle cell membrane depolarization | establishment of localization | response to metal ion | positive regulation of epithelial cell proliferation | membrane depolarization during action potential | voltage-gated ion channel activity | AV node cell to bundle of His cell signaling | membrane depolarization during atrial cardiac muscle cell action potential | cellular process | Purkinje myocyte to ventricular cardiac muscle cell signaling | localization | voltage-gated sodium channel activity involved in AV node cell action potential | passive transmembrane transporter activity | regulation of sodium ion transmembrane transport | metal ion transport | voltage-gated sodium channel activity involved in SA node cell action potential | response to inorganic substance | actin filament-based movement | atrial cardiac muscle cell action potential | regulation of cellular process | membrane depolarization during cardiac muscle cell action potential | voltage-gated sodium channel activity | transmembrane transporter activity | bundle of His cell action potential | heart contraction | ventricular cardiac muscle cell action potential | actin-mediated cell contraction | response to muscle inactivity | calcium ion homeostasis | cellular response to metal ion | regulation of atrial cardiac muscle cell membrane repolarization | muscle contraction | response to stimulus | ion gated channel activity | regulation of cell proliferation | regulation of blood circulation | regulation of cardiac muscle cell contraction | regulation of heart rate | cellular response to inorganic substance | blood circulation | neuronal action potential | cell-cell signaling | metal ion homeostasis | regulation of membrane potential | response to inactivity | system development | multicellular organism development | response to denervation involved in regulation of muscle adaptation | regulation of muscle contraction | ion transmembrane transport | SA node cell to atrial cardiac muscle cell communication | nervous system process | sodium ion transport | cation transmembrane transporter activity | regulation of membrane depolarization | monovalent inorganic cation transport | regulation of cellular component movement | cardiac muscle cell action potential involved in contraction | ion transmembrane transporter activity | bundle of His cell to Purkinje myocyte communication | SA node cell action potential | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | cell-cell signaling involved in cardiac conduction | regulation of heart contraction | cation homeostasis | regulation of striated muscle contraction | cell communication | regulation of atrial cardiac muscle cell membrane depolarization | membrane depolarization during SA node cell action potential | cardiac muscle cell contraction | regulation of cardiac muscle contraction | heart development | homeostatic process | positive regulation of cell proliferation | positive regulation of transport | striated muscle contraction | cation transmembrane transport | positive regulation of heart rate | cardiac ventricle development | regulation of heart rate by cardiac conduction | cellular response to calcium ion | response to organic substance | membrane depolarization during Purkinje myocyte cell action potential | atrial cardiac muscle cell to AV node cell communication | metal ion transmembrane transporter activity | anatomical structure development | voltage-gated sodium channel activity involved in Purkinje myocyte action potential | AV node cell action potential | AV node cell to bundle of His cell communication | cell communication involved in cardiac conduction | chemical homeostasis | membrane depolarization | sodium ion transmembrane transport | animal organ development | positive regulation of ion transport | positive regulation of sodium ion transport | SA node cell to atrial cardiac muscle cell signaling | ion homeostasis | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | cation channel activity | regulation of action potential | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | response to organic cyclic compound | monovalent inorganic cation transmembrane transporter activity | regulation of epithelial cell proliferation | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | developmental process | regulation of transport | cardiac muscle cell action potential | membrane depolarization during bundle of His cell action potential | cardiac chamber development | transmission of nerve impulse | response to calcium ion | ion channel activity | regulation of actin filament-based process | ion transport | cardiac muscle contraction | voltage-gated sodium channel activity involved in bundle of His cell action potential | circulatory system development | divalent inorganic cation homeostasis | substrate-specific channel activity | regulation of membrane repolarization | muscle system process | cardiac conduction | multicellular organismal process | membrane depolarization during AV node cell action potential
GO Cellular Component
supramolecular fiber | intercalated disc | integral component of membrane | voltage-gated sodium channel complex | intracellular membrane-bounded organelle | sarcolemma | neuron projection | sarcomere | cell | plasma membrane protein complex | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | contractile fiber | cell-cell junction | cell-cell contact zone | protein-containing complex | cell projection | endomembrane system | plasma membrane | membrane raft | integral component of plasma membrane | T-tubule | membrane-bounded organelle | organelle | I band | sodium channel complex | cell periphery | axon | transmembrane transporter complex | plasma membrane raft | cation channel complex | ion channel complex | Z disc | cell surface | intracellular | cell junction | caveola | lateral plasma membrane | membrane | supramolecular complex | intrinsic component of plasma membrane
