QuickView for SEC14L2;jsessionid=FEFB22F23A03FB9C1B562D32E6D1FB98;jsessionid=6803C818382B41D36E9620A010A09AE3 (gene)
- Gene Symbol:
- Sec14l2
Rattus norvegicus - Full name:
- SEC14-like lipid binding 2
- Synonyms:
- Spf, SEC14-like protein 2, TAP, alpha-tocopherol-associated protein, squalene transfer protein, supernatant protein factor
- Genomic Location:
- Chr 14: 84728484-84748418
- Description:
-
increases the activity of squalene epoxidase, which catalyzes the conversion of squalene to squalene 2,3-epoxide in cholesterol biosynthesis; may act as a cytosolic squalene transfer protein
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFKAPPAB_01 , NFKB_Q6 , NFKB_C , STAT1_01 , CCTNTMAGA_UNKNOWN , STAT1_02 , STAT1_03 , CTTTAAR_UNKNOWN , STAT_Q6 , YATTNATC_UNKNOWN
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
enzyme activator activity | lipid binding | transferase activity, transferring alkyl or aryl (other than methyl) groups | molecular function regulator | catalytic activity | transferase activity | enzyme regulator activity
GO Biological Process
RNA metabolic process | enzyme activator activity | cellular process | positive regulation of catalytic activity | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | positive regulation of cholesterol biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | positive regulation of lipid biosynthetic process | cellular nitrogen compound metabolic process | regulation of steroid biosynthetic process | cellular biosynthetic process | regulation of steroid metabolic process | molecular function regulator | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of catalytic activity | regulation of cholesterol biosynthetic process | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of cholesterol metabolic process | positive regulation of steroid metabolic process | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of lipid biosynthetic process | positive regulation of molecular function | positive regulation of steroid biosynthetic process | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | positive regulation of cholesterol metabolic process | transcription, DNA-templated | regulation of transcription, DNA-templated | enzyme regulator activity | cellular macromolecule biosynthetic process | heterocycle metabolic process | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
