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QuickView for SLC12A5;jsessionid=8E4B05A9F7398A6F6C6765DD0446E796;jsessionid=3274417983410A529F79EF480FA9770A (gene)


Gene Symbol:
Slc12a5 Rattus norvegicus Rattus norvegicus
Full name:
solute carrier family 12 member 5
Synonyms:
Kcc2, solute carrier family 12 member 5, K-Cl cotransporter 2, electroneutral potassium-chloride cotransporter 2, furosemide-sensitive K-Cl cotransporter, neuronal K-Cl cotransporter, neuronal-specific K-Cl cotransporter, rKCC2, solute carrier family 12 (potassium-chloride transporter), member 5
Genomic Location:
Chr 3: 156006017-156037915
Description:
neuronal specific potassium-chloride cotransporter isoform; may play a role in response to neuronal injury
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_134363
Protein Names
Q63633
A7Y821



GO Molecular Function

kinase binding | anion transmembrane transporter activity | ammonium transmembrane transporter activity | protein kinase binding | enzyme binding | transmembrane transporter activity | potassium:chloride symporter activity | inorganic anion transmembrane transporter activity | symporter activity | chloride transmembrane transporter activity | cation transmembrane transporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | protein binding | metal ion transmembrane transporter activity | potassium ion transmembrane transporter activity | secondary active transmembrane transporter activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | cation:chloride symporter activity

GO Biological Process

dendritic spine development | establishment of localization | anion transmembrane transporter activity | cell differentiation | nervous system development | response to drug | multicellular organism growth | cellular chemical homeostasis | neurogenesis | generation of neurons | cellular process | ammonium transmembrane transporter activity | localization | cellular homeostasis | metal ion transport | developmental growth | chemical synaptic transmission | neuron development | anion homeostasis | anion transport | learning | transmembrane transporter activity | thermosensory behavior | cellular component organization | pH reduction | chloride transmembrane transport | response to stimulus | intracellular pH reduction | response to stress | chloride transport | potassium:chloride symporter activity | inorganic anion transport | cellular monovalent inorganic anion homeostasis | response to temperature stimulus | regulation of cellular component size | inorganic anion transmembrane transporter activity | cell-cell signaling | hypotonic response | symporter activity | metal ion homeostasis | system development | multicellular organism development | chloride transmembrane transporter activity | learning or memory | potassium ion import | ion transmembrane transport | nervous system process | synaptic signaling | cation transmembrane transporter activity | cellular ion homeostasis | monovalent inorganic cation transport | active transmembrane transporter activity | cellular potassium ion transport | ion transmembrane transporter activity | potassium ion transport | cognition | response to osmotic stress | cation homeostasis | cellular cation homeostasis | cell communication | potassium ion homeostasis | regulation of intracellular pH | homeostatic process | neuron differentiation | cation transmembrane transport | cellular chloride ion homeostasis | regulation of pH | metal ion transmembrane transporter activity | anion transmembrane transport | anatomical structure development | chloride ion homeostasis | potassium ion transmembrane transporter activity | cell projection organization | chemical homeostasis | behavior | ammonium transmembrane transport | neuron projection development | ion homeostasis | inorganic cation transmembrane transport | secondary active transmembrane transporter activity | regulation of cellular pH | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | cellular monovalent inorganic cation homeostasis | monovalent inorganic cation transmembrane transporter activity | cell development | regulation of cell size | cation transport | ammonium transport | dendrite development | developmental process | potassium ion transmembrane transport | cation:chloride symporter activity | ion transport | cell volume homeostasis | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell projection membrane | cell body | cell | neuronal cell body | intrinsic component of membrane | dendritic tree | leading edge membrane | cell projection | plasma membrane | perikaryon | cell leading edge | integral component of plasma membrane | dendrite membrane | dendritic shaft | cell periphery | membrane | neuron projection membrane | intrinsic component of plasma membrane