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QuickView for SLC6A3;jsessionid=94F051D064CD768EF6DB1C96518852E5;jsessionid=0C6F4C944C8AF89DE5745D24F4951C31 (gene)


Gene Symbol:
Slc6a3 Rattus norvegicus Rattus norvegicus
Full name:
solute carrier family 6 member 3
Synonyms:
Dat1, sodium-dependent dopamine transporter, DA transporter, DAT, solute carrier family 6 (neurotransmitter transporter), member 3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Genomic Location:
Chr 1: 30515132-30557507
Description:
acts as a sodium-dependent dopamine transporter; may play a role in regulation of dopamine metabolism and signaling
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Canis lupus familiaris Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene


Transcripts Names
NM_012694
Protein Names
P23977



GO Molecular Function

anion transmembrane transporter activity | protein phosphatase 2A binding | dopamine:sodium symporter activity | cation binding | ammonium transmembrane transporter activity | neurotransmitter transporter activity | enzyme binding | protein-containing complex binding | transmembrane transporter activity | dopamine binding | signaling receptor binding | inorganic anion transmembrane transporter activity | symporter activity | protein N-terminus binding | chloride transmembrane transporter activity | cation transmembrane transporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | sodium:chloride symporter activity | protein binding | protein phosphatase binding | metal ion transmembrane transporter activity | sodium ion transmembrane transporter activity | secondary active transmembrane transporter activity | monoamine transmembrane transporter activity | neurotransmitter:sodium symporter activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | drug binding | protease binding | phosphatase binding | cation:chloride symporter activity | metal ion binding | solute:sodium symporter activity

GO Biological Process

brain development | catechol-containing compound metabolic process | establishment of localization | anion transmembrane transporter activity | positive regulation of developmental process | response to metal ion | nervous system development | response to drug | dopamine:sodium symporter activity | prepulse inhibition | response to antibiotic | dopamine transport | phenol-containing compound metabolic process | response to organophosphorus | cellular process | secretion | organic substance catabolic process | ammonium transmembrane transporter activity | localization | metal ion transport | neurotransmitter transporter activity | anion transport | catecholamine catabolic process | regulation of multicellular organism growth | diencephalon development | response to inorganic substance | regulation of cellular process | regulation of metabolic process | pituitary gland development | catabolic process | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | head development | chloride transmembrane transport | response to stimulus | response to cocaine | chloride transport | inorganic anion transport | organic hydroxy compound transport | response to alcohol | regulation of dopamine metabolic process | catecholamine biosynthetic process | dopamine uptake | cellular biosynthetic process | positive regulation of multicellular organism growth | response to iron ion | inorganic anion transmembrane transporter activity | adenohypophysis development | dopamine metabolic process | drug catabolic process | symporter activity | response to ethanol | regulation of catecholamine metabolic process | organic hydroxy compound metabolic process | response to nitrogen compound | response to nicotine | system development | nitrogen compound metabolic process | multicellular organism development | chloride transmembrane transporter activity | response to purine-containing compound | mammary gland development | ion transmembrane transport | dopamine catabolic process | organic substance transport | nervous system process | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | response to ammonium ion | regulation of nitrogen compound metabolic process | active transmembrane transporter activity | dopamine biosynthetic process | ion transmembrane transporter activity | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | startle response | response to toxic substance | response to xenobiotic stimulus | endocrine system development | regulation of cellular metabolic process | drug transmembrane transporter activity | aromatic compound catabolic process | sodium:chloride symporter activity | drug metabolic process | cation transmembrane transport | regulation of growth | response to organic substance | gland development | catecholamine metabolic process | lactation | metal ion transmembrane transporter activity | anion transmembrane transport | anatomical structure development | metabolic process | regulation of body fluid levels | behavior | body fluid secretion | ammonium transmembrane transport | sodium ion transmembrane transport | organic substance metabolic process | animal organ development | forebrain development | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | response to alkaloid | secondary active transmembrane transporter activity | response to cAMP | drug transport | sensory perception | monoamine transmembrane transporter activity | organonitrogen compound catabolic process | neurotransmitter:sodium symporter activity | transmembrane transport | positive regulation of developmental growth | positive regulation of growth | inorganic cation transmembrane transporter activity | response to organic cyclic compound | monovalent inorganic cation transmembrane transporter activity | neuromuscular process | regulation of developmental growth | sensory perception of chemical stimulus | drug transmembrane transport | cation transport | ammonium transport | regulation of developmental process | developmental process | monoamine transport | neurotransmitter transport | response to organonitrogen compound | cation:chloride symporter activity | central nervous system development | response to anesthetic | ion transport | cellular metabolic process | sensory perception of smell | aging | solute:sodium symporter activity | multicellular organismal process

GO Cellular Component

synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | membrane microdomain | presynapse | protein-containing complex | cell projection | plasma membrane | membrane raft | flotillin complex | cell periphery | axon | plasma membrane raft | cell surface | caveola | membrane