QuickView for SMPD1;jsessionid=6905F3D27E7D16105FE5A7D1359E9A52;jsessionid=352588EE1410638873DF4EB5A51A07B5 (gene)
- Gene Symbol:
- Smpd1
Mus musculus - Full name:
- sphingomyelin phosphodiesterase 1, acid lysosomal
- Synonyms:
- A-SMase, ASM, Zn-SMase, aSMase, sphingomyelin phosphodiesterase, acid sphingomyelinase
- Genomic Location:
- Chr 7: 112702929-112706896
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
acid sphingomyelin phosphodiesterase activity | cation binding | phospholipase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | hydrolase activity, acting on glycosyl bonds | ion binding | lipase activity | sphingomyelin phosphodiesterase activity | zinc ion binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | transition metal ion binding | metal ion binding
GO Biological Process
negative regulation of phosphorylation | regulation of dephosphorylation | negative regulation of MAPK cascade | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | response to drug | organophosphate catabolic process | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | phospholipid metabolic process | positive regulation of dephosphorylation | cellular process | organic substance catabolic process | negative regulation of signaling | sphingolipid metabolic process | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | cellular lipid metabolic process | response to stimulus | positive regulation of protein metabolic process | response to cocaine | negative regulation of protein kinase activity | cellular nitrogen compound biosynthetic process | ceramide metabolic process | sphingolipid biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | positive regulation of protein dephosphorylation | response to nitrogen compound | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | organophosphate metabolic process | positive regulation of cellular metabolic process | response to ammonium ion | regulation of nitrogen compound metabolic process | negative regulation of protein serine/threonine kinase activity | cellular amide metabolic process | phospholipid catabolic process | biosynthetic process | regulation of cellular protein metabolic process | lipid biosynthetic process | membrane lipid catabolic process | response to xenobiotic stimulus | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | sphingomyelin catabolic process | cellular lipid catabolic process | sphingomyelin metabolic process | regulation of protein metabolic process | regulation of protein phosphorylation | negative regulation of MAP kinase activity | positive regulation of protein modification process | response to organic substance | regulation of protein dephosphorylation | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | membrane lipid metabolic process | positive regulation of cell death | lipid catabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | amide biosynthetic process | positive regulation of programmed cell death | regulation of phosphate metabolic process | response to alkaloid | negative regulation of protein metabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | response to organic cyclic compound | response to organonitrogen compound | sphingolipid catabolic process | response to anesthetic | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | ceramide biosynthetic process | termination of signal transduction | regulation of signaling | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | secretory vesicle | endomembrane system | plasma membrane | vacuole | vesicle | lytic vacuole | endosome | extracellular region | membrane-bounded organelle | organelle | lysosome | extracellular space | cell periphery | lamellar body | intracellular vesicle | intracellular | membrane
